Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- B2020
Neuromuscular activation analysis of the trunk muscles during hippotherapy sessions
Júlio Ribeiro Bravo Gonçalves Junior, André Gustavo Fernandes de Oliveira, Silvia Almeida Cardoso, Kamila Gabriela Jaco…This study investigated how hippotherapy (therapeutic horseback riding) affects trunk muscle activation in children. Researchers measured the activity of four key back and shoulder muscles during a 30-minute session, co…
HippotherapyElectromyographyMuscle activation - A+++2020
The feasibility and impact of instrument-assisted manual therapy (IAMT) for the lower back on the structural and functional properties of the lumbar area in female soccer players: a randomised, placebo-controlled pilot study design
Patrick Weber, Christine Graf, Werner Klingler, Nadine Weber, Robert SchleipThis is a protocol for a pilot study designed to investigate the feasibility and impact of instrument-assisted manual therapy (IAMT) for the lower back in female soccer players. The researchers plan to compare IAMT with…
Thoracolumbar fasciaMyofascialultrasound.AthletesInstrument-assisted - A++2020
The Structure and Role of Intramuscular Connective Tissue in Muscle Function
Peter P PurslowThis narrative review analyzes the microscopic structure of intramuscular connective tissue—endomysium, perimysium, and epimysium—and its role in muscle function. Rather than acting simply as a container, this connectiv…
extracellular matrixMusclecollagenmechanotransductionperimysium - A+++2020
Ascorbate as Prophylaxis and Therapy for COVID-19—Update From Shanghai and U.S. Medical Institutions
Richard Z Cheng, Mikhail Kogan, Devra DavisThis 2020 report describes how a medical panel in Shanghai evaluated the use of intravenous (IV) ascorbate, or vitamin C, for patients with severe COVID-19. The panel reviewed existing studies and preliminary data from…
COVID-19public healthglobal healthintravenous ascorbate - A2020
A Novel Role of Ascorbic Acid in Anti-Inflammatory Pathway and ROS Generation in HEMA Treated Dental Pulp Stem Cells
Francesca Diomede, Guya Diletta Marconi, Simone Guarnieri, Michele D’Attilio, Marcos F X B Cavalcanti, Maria A Mariggiò…Components from common dental resins can sometimes cause inflammation and oxidative stress in the cells of the dental pulp. This laboratory study investigated whether ascorbic acid (Vitamin C) could protect human dental…
human dental pulp stem cells; hema; ascorbic acid; nfkb; erk; perk; inflammatory cytokines - A+++2020
Is the VITAMINS RCT indicating potential redundancy between corticosteroids and vitamin C?
Anitra C CarrKnown only by its title, this article appears to be a commentary or analysis of a randomized controlled trial (RCT) known as VITAMINS. The title poses a question about whether there might be a "redundancy," or overlappi…
Vitamin Ccorticosteroidsstress respons - A+++2020
Overview of the possible role of vitamin C in management of COVID-19
Anis Abobaker, Aboubaker Alzwi, Alsalheen Hamed A AlraiedIn this 2020 review, the authors examine the possible role of vitamin C in managing COVID-19. They note that the body's vitamin C levels often drop during an acute infection due to increased metabolic demands. Because v…
Vitamin CCOVID-19SARS-CoV-2Beneficial effectsManagement - A2020
Anatomy, Tendons
Bruno Bordoni, Matthew VaracalloThis is a placeholder for a summary of a publication titled "Anatomy, Tendons". The full text has not yet been reviewed by our team. Once summarized, this entry will provide an overview of the key anatomical features of…
fasciatendonsAnatomytendon sheaths - A+++2020
An anatomical comparison of the fasciae of the thigh: A macroscopic, microscopic and ultrasound imaging study
Carmelo Pirri, Caterina Fede, Lucia Petrelli, Diego Guidolin, Chenglei Fan, Raffaele De Caro, Carla SteccoResearchers compared the thigh's fascial layers using three methods: dissection of cadavers, microscopic analysis, and ultrasound imaging of living volunteers. They identified distinct layers, including a superficial fa…
fascia lataImagingThicknessmusculo-skeletal ultrasoundsuperficial fascia - A+2020
Ankle Motion Is Associated With Soft Tissue Displacement in the Dorsal Thigh: An in vivo Investigation Suggesting Myofascial Force Transmission Across the Knee Joint
Jan Wilke, Heloise Debelle, Sarah Tenberg, Andrew Dilley, Constantinos MaganarisThis study investigated how ankle motion affects tissue in the back of the thigh. Researchers passively stretched the calves of healthy participants lying prone with an extended knee. Using ultrasound, they observed tha…
fasciamyofascial chainsultrasound.Myofascial force transmissionrange of motion - A+++2020
Effects of Cesarean Section and Vaginal Delivery on Abdominal Muscles and Fasciae
Chenglei Fan, Diego Guidolin, Serena Ragazzo, Caterina Fede, Carmelo Pirri, Nathaly Gaudreault, Andrea Porzionato, Vero…This study used ultrasound to compare the abdominal muscles and fascia of women who had a C-section, a vaginal delivery, or had never given birth. Researchers found that both types of delivery were associated with chang…
caesarean section; vaginal delivery; fascia; abdominal muscles; pain; ultrasound - A+++2020
Antiviral Mechanisms of Vitamin C: A Short Communication Consensus Report
Michael J Gonzalez, Jorge R Miranda-Massari, Jose R Rodriguez, Victor Marcial-Vega, Miguel J Berdiel, Jorge Duconge, St…This 2020 publication is a consensus report from a large group of authors, summarizing agreed-upon points regarding vitamin C. Based on the title, the report details the various mechanisms by which vitamin C may exert a…
Vitamin CAscorbic acidantiviral effects