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The Fascia Guide
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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 13–17 of 17 studies · page 2/2extracellular matrixSince 2015
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  1. C
    2016

    Protein—glycosaminoglycan interaction networks: Focus on heparan sulfate

    Sylvie Ricard-Blum

    This research overview describes a project focused on glycosaminoglycans (GAGs), complex sugars found on the cell surface and in the extracellular matrix. Specifically, it investigates heparan sulfate and how it interac…

    extracellular matrixHeparan sulfateInteraction networksInteraction databasesSurface plasmon resonance
  2. B
    2015

    Platelet hyaluronidase-2: an enzyme that translocates to the surface upon activation to function in extracellular matrix degradation

    Sami Albeiroti, Katayoun Ayasoufi, [...], Carol A de la Motte

    Platelets play a key role in responding to tissue injury. This study explores how they interact with hyaluronan, a major component of the extracellular matrix that is involved in inflammation. Researchers demonstrated t…

    hyaluronanextracellular matrixDegradationhyaluronidas-2HYAL2
  3. A
    2015

    Modes of cancer cell invasion and the role of the microenvironment

    Andrew G Clark, Danijela Matic Vignjevic

    For cancer to spread, or metastasize, tumor cells must first invade the surrounding connective tissue (stroma). This review article describes how cancer cells can move in different ways—either as single cells or in coll…

    fasciaextracellular matrixcancertumor invasionmicroenvironment
  4. B
    2015

    The extracellular matrix: Tools and insights for the “omics” era

    A Nabaa, K R Clauser, H Dingd, C A Whittaker, S A Carrc, R O Hynesa

    This narrative review discusses the extracellular matrix (ECM), the complex network of proteins and molecules that provides structural and chemical support to our cells and tissues. Alterations in the ECM are associated…

    extracellular matrixMatrisomeMatrisomeDBECM atlasBioinformatics
  5. A
    2015

    Remodelling the extracellular matrix in development and disease

    Caroline Bonnans, Jonathan Chou, Zena Werb

    This narrative review describes the extracellular matrix (ECM), a dynamic network present in all body tissues that undergoes constant remodeling. This remodeling process is crucial for regulating cell functions like pro…

    fasciaextracellular matrixstiffnessmechanotransductionmatrix remodeling