Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesImaging of Ultraweak Spontaneous Photon Emission from Human Body Displaying Diurnal Rhythm
The human body emits an extremely faint light, about 1000 times dimmer than what our naked eyes can detect. This phenomenon, known as ultraweak photon emission, is thought to be linked to the body's energy metabolism. U…
Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators
This 2008 review article explores how collagen fibrils, the main structural components of connective tissue, are formed. While collagen can self-assemble in a test tube, the process in living tissues is carefully manage…
Tensegrity-Based Mechanosensing from Macro to Micro
This review article, based on a lecture, explores how cells convert mechanical signals into biochemical responses. The author proposes that the body uses "tensegrity" (tensional integrity) principles, where interconnect…
Humoral phototransduction: Light transportation in the blood, and possible biological effects
In this theoretical paper, researchers propose a model called 'humoral phototransduction' to explain how light might affect the body beyond the eyes. They observed that blood plasma, and particularly the protein albumin…
Dorsal horn neurons having input from low back structures in rats
In this animal study, researchers in rats investigated how spinal cord nerve cells (dorsal horn neurons) process signals from the low back. They found that these neurons often receive input from several different tissue…
Tensegrity and Mechanotransduction
This article summarizes a lecture on how mechanical forces influence biological processes at the cellular level. The author describes mechanotransduction, the process by which cells convert physical forces into biochemi…
Fibronectin Unfolding Revisited: Modeling Cell Traction- Mediated Unfolding of the Tenth Type-III Repeat
Cells build the extracellular matrix by pulling on the protein fibronectin, causing it to assemble into fibrils. This study used computer simulations to investigate how this process works at a molecular level. Researche…
Mechanotransduction – a field pulling together?
In this 2008 review article, the author discusses mechanotransduction, the process by which cells convert mechanical forces into biochemical signals. Cells are constantly subjected to forces, both from external pressure…
Three-Dimensional Mathematical Model for Deformation of Human Fasciae in Manual Therapy
Researchers developed a mathematical model to calculate the force required to deform human fascia during manual therapy. The model showed that very large forces, beyond the normal physiological range of a therapist, are…
Can cancer be reversed by engineering the tumor microenvironment?
In this perspective article, the author proposes a different way of looking at cancer. Instead of focusing solely on genetic mutations, he argues that the physical environment around a tumor, particularly the extracellu…
Tissue Stretch Decreases Soluble TGF-β1 and Type-1 Procollagen in Mouse Subcutaneous Connective Tissue: Evidence From Ex Vivo and In Vivo Models
This study on mice investigated how brief, static stretching affects connective tissue healing after an injury. Researchers used two models: tissue samples cultured outside the body (ex vivo) and live mice with minor su…
Differential effects of hyaluronan and its fragments on fibroblasts: Relation to wound healing
This lab study investigated how hyaluronan (HA) of different molecular sizes affects human fibroblast cells, which are key to wound healing. Researchers exposed fibroblasts to native HA and two smaller fragments. All th…