Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

with plain-language summary

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Showing 193–204 of 218 studies · page 17/19fascia

A++
2009
Imaging of Ultraweak Spontaneous Photon Emission from Human Body Displaying Diurnal Rhythm
Masaki Kobayashi, Daisuke Kikuchi, Hitoshi Okamura
The human body emits an extremely faint light, about 1000 times dimmer than what our naked eyes can detect. This phenomenon, known as ultraweak photon emission, is thought to be linked to the body's energy metabolism. U…
fasciabiophotonsultraweak photonsdiurnal rhythm
A
2008
Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators
Karl E Kadler, Adele Hill, Elizabeth G Canty-Laird
This 2008 review article explores how collagen fibrils, the main structural components of connective tissue, are formed. While collagen can self-assemble in a test tube, the process in living tissues is carefully manage…
fasciaIntegrinsFibronectincollagen fibrillogenesis
A
2008
Tensegrity-Based Mechanosensing from Macro to Micro
Donald E Ingber
This review article, based on a lecture, explores how cells convert mechanical signals into biochemical responses. The author proposes that the body uses "tensegrity" (tensional integrity) principles, where interconnect…
fasciaextracellular matrixTensegritycytoskeletonmechanotransduction
A++
2008
Humoral phototransduction: Light transportation in the blood, and possible biological effects
F Grass, S Kasper
In this theoretical paper, researchers propose a model called 'humoral phototransduction' to explain how light might affect the body beyond the eyes. They observed that blood plasma, and particularly the protein albumin…
fasciabiophotonsultraweak photonshumoral phototransduction
A
2008
Dorsal horn neurons having input from low back structures in rats
T Taguchi, U Hoheisel, S Mense
In this animal study, researchers in rats investigated how spinal cord nerve cells (dorsal horn neurons) process signals from the low back. They found that these neurons often receive input from several different tissue…
fascialow back painmultifidus muscledorsal horn neuronsnerve growth factor (NGF)
A
2008
Tensegrity and Mechanotransduction
D E Ingber
This article summarizes a lecture on how mechanical forces influence biological processes at the cellular level. The author describes mechanotransduction, the process by which cells convert physical forces into biochemi…
fasciaTensegritycytoskeletonmechanotransductionIntegrins
A
2008
Fibronectin Unfolding Revisited: Modeling Cell Traction- Mediated Unfolding of the Tenth Type-III Repeat
Elaine P S Gee, Donald E Ingber, Collin M Stultz
Cells build the extracellular matrix by pulling on the protein fibronectin, causing it to assemble into fibrils. This study used computer simulations to investigate how this process works at a molecular level. Researche…
fasciaFibronectincell tractionintegrinfibrillogenesis
A
2008
Mechanotransduction – a field pulling together?
Christopher S Chen
In this 2008 review article, the author discusses mechanotransduction, the process by which cells convert mechanical forces into biochemical signals. Cells are constantly subjected to forces, both from external pressure…
fasciastiffnessmechanobiologycell adhesionmechanical force
A
2008
Three-Dimensional Mathematical Model for Deformation of Human Fasciae in Manual Therapy
Hans Chaudhry, Robert Schleip, Zhiming Ji, Bruce Bukiet, Miriam Maney, Thomas Findley
Researchers developed a mathematical model to calculate the force required to deform human fascia during manual therapy. The model showed that very large forces, beyond the normal physiological range of a therapist, are…
fasciaManual Therapyplantar fasciachiropractic manipulationsoft tissue motion
A
2008
Can cancer be reversed by engineering the tumor microenvironment?
Donald E Ingber
In this perspective article, the author proposes a different way of looking at cancer. Instead of focusing solely on genetic mutations, he argues that the physical environment around a tumor, particularly the extracellu…
fasciaextracellular matrixmechanicalcytoskeletonstroma
1A+
2008
Tissue Stretch Decreases Soluble TGF-β1 and Type-1 Procollagen in Mouse Subcutaneous Connective Tissue: Evidence From Ex Vivo and In Vivo Models
N A Bouffard, K R Cutroneo, G J Badger, S L White, T R Buttolph, H P Ehrlich, D Stevens-Tuttle, H M Langevin
This study on mice investigated how brief, static stretching affects connective tissue healing after an injury. Researchers used two models: tissue samples cultured outside the body (ex vivo) and live mice with minor su…
fasciaConnective tissueStretchingManual TherapyMovement Therapy
A
2008
Differential effects of hyaluronan and its fragments on fibroblasts: Relation to wound healing
Maha David-Raoudi, Frederic Tranchepain, Brigitte Deschrevel, Jean-Claude Vincent, Patrick Bogdanowicz, Karim Boumedien…
This lab study investigated how hyaluronan (HA) of different molecular sizes affects human fibroblast cells, which are key to wound healing. Researchers exposed fibroblasts to native HA and two smaller fragments. All th…
hyaluronanfasciawound healingextracellular matrixfibrosis