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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 193–204 of 247 studies · page 17/21Since 2020
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A2020

Low-intensity vibration restores nuclear YAP levels and acute YAP nuclear shuttling in mesenchymal stem cells subjected to simulated microgravity

Matthew Thompson, Kali Woods, Joshua Newberg, Julia Thom Oxford, Gunes Uzer

Astronauts lose bone and muscle in space, partly because their cells become less responsive to mechanical forces. This study investigated if low-intensity vibration (LIV) could help counteract this effect in a lab setti…

vibrationsstem cellsmicrogravity
A+++2020

Fasting-mimicking diet plus chemotherapy in breast cancer treatment

Claudio Vernieri, Francesca Ligorio, Emma Zattarin, Licia Rivoltini, Filippo de Braud

This clinical trial investigated whether a fasting-mimicking diet (FMD) combined with chemotherapy could improve outcomes for breast cancer patients. The overall results were negative, meaning the study did not find a s…

fasting; fasting-mimicking diet; inflammation; intermittent fasting; breast cancer
A2020

Evaluation of scapular mobilization and comparison to pectoralis minor stretching in individuals with rounded shoulder posture: A randomized controlled trial

Maedeh Fani, Samaneh Ebrahimi, Ali Ghanbari

This randomized controlled trial investigated treatments for rounded shoulder posture in 52 healthy students. Researchers compared the effects of scapular mobilization, pectoralis minor self-stretching, and a combinatio…

Mobilization; Pectoralis minor stretching; Rounded shoulder; Scapular kinematics.
A2020

Lymphatic treatments after orthopedic surgery or injury: A systematic review

Ifat Klein, Dorit Tidhar, Leonid Kalichman

This systematic review examined the effectiveness of lymphatic and compression therapies for reducing swelling and pain after orthopedic surgery or injury. Researchers analyzed 15 studies, finding that for persistent sw…

Compression therapy; Edema; Lymphatic therapy; Orthopedic surgery; Postoperative treatment.
A++2020

Simulation and Modeling of Telocytes Behavior in Signaling and Intercellular Communication Processes

Dragos Cretoiu, Simona Roatesi, Ion Bica, Cezar Plesca, Amado Stefan, Oana Bajenaru, Carmen Elena Condrat, Sanda Maria…

Telocytes are a unique type of interstitial cell with long extensions that form networks, thought to be involved in local tissue equilibrium and regeneration. In this study, researchers used computer simulation and math…

content-based image retrieval; image indexation; modeling of living cell behavior; telocyte network tracking and indexing; telocytes; viscoelastic constitutive laws
A++2020

Applicability of Low-intensity Vibrations as a Regulatory Factor on Stem and Progenitor Cell Populations

Oznur Baskan, Ozge Karadas, Gulistan Mese, Engin Ozcivici

This narrative review explores how mechanical forces, specifically low-intensity vibrations, can influence stem cells. While high-impact activities like running are known to build tissue, they are not suitable for every…

Stem cell; biomechanics; mechanobiology; progenitor cell populations; tissue engineering; vibrations
A2020

Role of fascial connectivity in musculoskeletal dysfunctions: A narrative review

M S Ajimsha, Pramod D Shenoy, Neeraj Gampawar

This narrative review examines the concept of "fascial connectivity," which suggests that muscles and fascia are linked in functional chains throughout the body. The authors analyzed 35 studies, including cadaveric, ani…

Fascia; Fascial connectivity; Myofascial chains; Myofascial meridians.
A+++2020

Propolis-induced exclusion of colloids: Possible new mechanism of biological action

Magdalena Kowacz, Gerald H Pollack

This laboratory study investigates how propolis (bee glue) interacts with water to create an exclusion zone (EZ)—a layer of water that repels solutes and microorganisms. The researchers found that surfaces coated with p…

Colloid-surface repulsion; Exclusion zone; Propolis
A2020

PIEZO2: A Novel Molecule Involved in the Development of AIS

Zhichong Wu, Yuwen Wang, Chao Xia, Zhenhua Feng, Yong Qiu, Jack Chun-Yiu Cheng, Leilei Xu, Zezhang Zhu

This case-control study investigated the potential link between the PIEZO2 gene, proprioception (the body's sense of position), and adolescent idiopathic scoliosis (AIS). Researchers found that AIS patients often exhibi…

proprioceptionpiezo2AIS
B2020

Sympathetic activation: a potential link between comorbidities and COVID-19

Andrea Porzionato, Aron Emmi, Silvia Barbon, Rafael Boscolo-Berto, Carla Stecco, Elena Stocco, Veronica Macchi, Raffael…

In this perspective article, researchers propose a potential link between common comorbidities and severe COVID-19 outcomes. Conditions like heart disease, hypertension, and diabetes, which are risk factors for severe C…

autonomic nervous system; COVID-19; diabetes; heart failure; hypertension; kidney disease; obesity; SARS-CoV-2; smoking; sympathoactivation
A2020

Pilates exercise improves the clinical and immunological pro!les of patients with human T-cell lymphotropic virus 1 associated myelopathy: A pilot study

Altair Vallinoto Klautau, Denise da Silva Pinto, Bárbara Brasil Santana, Maria Alice Freitas Queiroz, Andréa Nazar!e M…

This pilot study investigated the effects of a 10-week Pilates program for eight patients with the chronic inflammatory disease HAM/TSP. After the exercise period, participants experienced significant improvements in pa…

cytokinesHTLV-1HTLV-1-Associated myelopathy
A+++2020

The role of cannabinoids in the treatment of cancer

L Vecera, T Gabrhelik, P Prasil, P Stourac

This review article summarizes current knowledge on how cannabinoids and their receptors modulate tumor diseases. Research suggests that cannabinoids may influence cancer progression by stimulating programmed cell death…

cancer; cannabinoid receptor; cannabinoids; oncological diseases cancer treatment