Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2020
Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women
Jay Jay Thaung Zaw, Peter R C Howe, Rachel H X WongThis randomized controlled trial investigated how daily resveratrol supplementation affects brain health in postmenopausal women over a 12-month period. Participants took either 75 mg of trans-resveratrol twice daily or…
ageing; cerebrovascular function; cognitive decline; menopause; neurovascular coupling; nutraceutical; phytoestrogen; resveratrol - A2020
Ageing of the diaphragm muscle
Bruno Bordoni, Bruno Morabito, Marta SimonelliThis narrative review explores how the diaphragm, our main breathing muscle, is affected by aging. Like other muscles, the diaphragm can weaken and lose mass over time, a condition known as sarcopenia. This age-related…
fasciadiaphragmskeletal musclephrenic nervevagus nerve - A2020
Whole body vibration in the static modified push-up position in untrained healthy women stimulates neuromuscular system potentiating increased handgrip myogenic response
Ana Lúcia Cristino de Souza, Vanessa Amaral Mendonca, Ana Carolina Coelho de Oliveira, Sueli Ferreira da Fonseca, Lucia…This study investigated the acute effects of vibration on handgrip strength in untrained women. Participants placed their hands on a vibrating platform in a modified push-up position for five minutes. Researchers found…
Electromyography; Exposure to vibration; Grip strength; Muscular performance. - A++2020
Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk
Lijun Wang, Xiuling You, Sutada Lotinun, Lingli Zhang, Nan Wu, Weiguo ZouThis study using mouse models investigates how the protein PIEZO1 acts as a mechanical sensor in the skeleton to regulate bone mass. Researchers found that a deficiency of PIEZO1 in bone-forming cells (osteoblasts) lead…
mechanotransductionpiezobone homeostasis - A+++2020
Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts
Torsten Lowin, Ren Tingting, Julia Zurmahr, Tim Classen, Matthias Schneider, Georg PongratzThis laboratory study investigated how cannabidiol (CBD) affects synovial fibroblasts, the cells responsible for joint destruction in rheumatoid arthritis. Researchers found that CBD can reduce the viability of these ce…
inflammationfibroblastCannabinoidsrheumatoid arthritissynovia - A++2020
Integrating mental imagery and fascial tissue: A conceptualization for research into movement and cognition
Amit Abraham, Eric Franklin, Carla Stecco, Robert SchleipThis narrative review explores the connection between mental imagery and fascial tissue, a field that has historically focused on muscles and the nervous system. The authors propose that specific mental visualizations d…
Body schema; Cognition; Dynamic neuro-cognitive imagery; Fascia; Mental imagery; Movement - A++2020
What is the Intelligent Tissue !eory and How Does it Relate to Acupuncture?
Fletcher KovichThis article introduces the "intelligent tissue theory," which proposes that organ information is transmitted via electromagnetic waves and interpreted by bodily tissues at specific meridians. The author suggests that t…
acupunctureChiintelligent tissueNei Jing - A+++2020
The Cranial Bowl in the New Millennium and Sutherland's Legacy for Osteopathic Medicine: Part 2
Bruno Bordoni, Stevan Walkowski, Bruno Ducoux, Filippo TobbiThis narrative review, the second in a series, discusses how modern scientific research challenges some of the original concepts of cranial osteopathy. The authors examine the mechanical characteristics of cranial struc…
fasciaManual TherapyOsteopathiccraniocraniosacral - A2020
Muscle Cramps
Bruno Bordoni, Kavin Sugumar, Matthew VaracalloMuscle cramps are involuntary, painful, and localized contractions of a muscle or muscle fibers, often felt as a palpable knot. While common in sports, their exact cause is not fully understood and likely depends on var…
Diagnosiscramp - A+++2020
A Potential Involvement of Anandamide in the Modulation of HO/NOS Systems: Women, Menopause, and "Medical Cannabinoids"
Renáta Szabó, Denise Börzsei, Zsuzsanna Szabó, Alexandra Hoffmann, István Zupkó, Dániel Priksz, Krisztina Kupai, Csaba…This animal study using an estrogen-deficient rat model investigated how the endocannabinoid anandamide (AEA) affects cardiovascular health during menopause-like conditions. Researchers found that estrogen loss reduced…
anandamide; cardiovascular system; heme oxygenase; nitric oxide synthase - A++++2020
Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths
William B Grant, Henry Lahore, Sharon L McDonnell, Carole A Baggerly, Christine B French, Jennifer L Aliano, Harjit P B…In this 2020 review article, the authors examine evidence that vitamin D could reduce the risk of respiratory tract infections, including influenza and COVID-19. They propose that vitamin D works through several mechani…
acute respiratory distress syndrome (ARDS); ascorbic acid; cathelicidin; coronavirus; COVID-19; cytokine storm; influenza; observational; pneumonia; prevention; respiratory tract infection; solar radiation; treatment; UVB; vitamin C; vitamin D - A2020
Low-intensity vibration restores nuclear YAP levels and acute YAP nuclear shuttling in mesenchymal stem cells subjected to simulated microgravity
Matthew Thompson, Kali Woods, Joshua Newberg, Julia Thom Oxford, Gunes UzerAstronauts lose bone and muscle in space, partly because their cells become less responsive to mechanical forces. This study investigated if low-intensity vibration (LIV) could help counteract this effect in a lab setti…
vibrationsstem cellsmicrogravity