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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 169–180 of 247 studies · page 15/21Since 2020
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A+++2020

Do Interventions with Diet or Dietary Supplements Reduce the Disease Activity Score in Rheumatoid Arthritis? A Systematic Review of Randomized Controlled Trials

Josefine Nelson, Helen Sjöblom, Inger Gjertsson, Stine M Ulven, Helen M Lindqvist, Linnea Bärebring

This systematic review examined randomized controlled trials to determine if diet or dietary supplements can reduce disease activity in adults with rheumatoid arthritis. The researchers found moderate-strength evidence…

DAS28; Rheumatoid Arthritis; diet
A+++2020

Cannabinoids in Medicine: Cancer, Immunity, and Microbial Diseases

Paweł Śledziński, Agnieszka Nowak-Terpiłowska, Joanna Zeyland

This narrative review explores how cannabinoids, including those from plants and those produced naturally by the body, influence health through the endocannabinoid system. The authors describe how these compounds intera…

cancer medicine; cannabinoid receptors; cannabinoids; immune medicine
A++2020

Sensitivity of the Fasciae to the Endocannabinoid System: Production of Hyaluronan-Rich Vesicles and Potential Peripheral Effects of Cannabinoids in Fascial Tissue

Caterina Fede , Carmelo Pirri , Lucia Petrelli, Diego Guidolin , Chenglei Fan, Raffaele De Caro, Carla Stecco

This laboratory study investigated how fascial cells respond to cannabinoids. Researchers isolated fibroblast cells from human fascia lata and treated them with a substance that activates cannabinoid receptor 2. The tre…

fascia; hyaluronan; vesicles; endocannabinoid; agonist; antagonist; inflammation; fibrosis; pain; peripheral effect
B2020

Cellular elements organization in the trachea of mallard (Anas platyrhynchos) with a special reference to its local immunological role

Doaa M Mokhtar, Marwa M Hussien

This animal study examined the cellular structure of the trachea (windpipe) in mallard ducks using light and electron microscopy. Researchers found a complex organization of cells that form the first line of defense aga…

Telocytes . Dendritic reticular cells . Immune cells . Mucous glands
A+2020

Role of vitamin K 2 in bone metabolism: a point of view and a short reappraisal of the literature

A Capozzi, G Scambia, S Migliaccio, S Lello

This narrative review examines the role of Vitamin K2 in bone metabolism and its contribution to maintaining skeletal integrity. Vitamin K2 is essential for activating osteocalcin, a key protein that binds calcium to th…

Vitamin K2; bone; fracture; menaquinone; osteoporosis
A+++2020

Healthy fats and exclusion-zone size

Abha Sharma, Gerald H Pollack

This study investigated whether healthy fats can contribute to the formation of exclusion-zone (EZ) water, also known as the fourth phase of water. Researchers tested substances such as ghee, coconut oil, and lard to se…

Coconut oil; Exclusion-zone water; Fats; Ghee; Health-promoting function; Lard; UV–VIS spectroscopy
A++2020

Extracellular Vesicles Released From Articular Chondrocytes Play a Major Role in Cell-Cell Communication

Xiaoming Liu, Claire Shortt, Fenglin Zhang, Mariah Q Bater, Mary K Cowman, Thorsten Kirsch

This narrative review examines the role of extracellular vesicles (EVs) as crucial mediators in cell-to-cell communication. EVs are small, lipid-enclosed particles that transport proteins, lipids, and genetic material t…

articular chondrocytes; catabolic events; chondrogenesis; extracellular vesicles
A++2020

Is the extent of obstetric anal sphincter injury correlated with the severity of fecal incontinence in the long term?

L Luciano, M. Bouvier, K Baumstarck, V Vitton

This retrospective study investigated the relationship between the extent of obstetric anal sphincter injury and the severity of long-term fecal incontinence (FI). Researchers analyzed data from 250 women with a mean ag…

Fecal incontinence · Obstetrical anal sphincter injury · Endoanal ultrasonography · 3D high-resolution anorectal manometry · Delivery
A++2020

The potential of cannabidiol in the COVID-19 pandemic

Giuseppe Esposito, Marcella Pesce, Luisa Seguella, Walter Sanseverino, Jie Lu, Chiara Corpetti, Giovanni Sarnelli

This scientific hypothesis explores the potential of cannabidiol (CBD) as a supportive treatment during the COVID-19 pandemic. The authors suggest that CBD may down-regulate the receptors the virus uses for cellular ent…

fibrosisCannabinoidsimmune system
A+++2020

Cannabis and cannabidiol (CBD) for the treatment of fibromyalgia

Amnon A Berger, Joseph Keefe, Ariel Winnick, Elasaf Gilbert, Jonathan P Eskander, Cyrus Yazdi, Alan D Kaye, Omar Viswan…

This narrative review examines the use of cannabis and cannabidiol (CBD) for treating fibromyalgia, a complex condition that often responds poorly to standard therapies. The authors note that while high-quality randomiz…

CBT; SNRI; SSRI; chronic pain; depression; myalgia.
A2020

Comparison of the therapeutic outcomes between open plantar fascia release and percutaneous radiofrequency ablation in the treatment of intractable plantar fasciitis

Yusong Yuan, Yuan Qian, Hao Lu, Yuhui Kou, Yangbo Xu, Hailin Xu

This retrospective study compared two surgical treatments for severe, persistent plantar fasciitis: open plantar fascia release and percutaneous radiofrequency ablation. Researchers analyzed outcomes for 31 patients nea…

Intractable plantar fasciitisOpen plantar fascia releasePercutaneous radiofrequency ablation
A2020

Neuroanatomy, Cranial Nerve 11 (Accessory)

Bruno Bordoni, Ryder R Reed, Prasanna Tadi, Matthew Varacallo

This review article describes the anatomy and function of the 11th cranial nerve, the accessory nerve. This nerve is essential for neck and shoulder movement, controlling key muscles like the trapezius and sternocleidom…

cranial nerve XIaccessory nerve