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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 157–168 of 247 studies · page 14/21Since 2020
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A++2020

Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections

Philip C Calder, Anitra C Carr, Adrian F Gombart, Manfred Eggersdorfer

In this review, the authors state that optimal nutritional status is crucial for a well-functioning immune system and protection against viral infections. They highlight that many vitamins (A, B6, B12, C, D, E, folate),…

immune system; viral infection; influenza; COVID-19; micronutrients; vitamins; omega-3 fatty acids; minerals; vitamin C; vitamin D
A+++2020

Om vikten av att stärka immunförsvaret under covid-19

Mats Humble, Bo Jonsson, Per Kågeson

This memo summarizes the state of knowledge on strengthening the immune system in the elderly to better manage COVID-19. The authors focus on findings that highlight the importance of maintaining adequate levels of spec…

VitaminsImmune system
B2020

Bicarbonate use and mortality outcome among critically ill patients with metabolic acidosis: A meta analysis

Kevin Bryan Lo, Veronica Garvia, Jessica M Stempel, Pradhum Ram, Janani Rangaswami

This meta-analysis investigated whether treating critically ill patients with sodium bicarbonate for metabolic acidosis, a condition of excess acid in the blood, affects mortality. The use of bicarbonate in intensive ca…

Bicarbonate; ICU; Meta analysis; Metabolic acidosis; Mortality
A2020

Structural remodelling of the lumbar multifidus, thoracolumbar fascia and lateral abdominal wall perimuscular connective tissues: A cross-sectional and comparative ultrasound study

Christian Lariviére, Richard Preuss, Dany H Gagnon, Hakim Mecheri, Sharon M Henry

Researchers used ultrasound to compare soft tissues in the lower back and abdomen of people with and without non-acute low back pain (LBP). They measured the multifidus muscle, the thoracolumbar fascia, and the connecti…

Low back pain; Multifidus fatty/fibrosis infiltration; Perimuscular connective tissues; Sex; Ultrasound imaging.
A2020

The relaxin family peptide receptor 1 (RXFP1): An emerging player in human health and disease

Ting-Yun Chen, Xiaoyun Li, Ching-Hsia Hung, Harinath Bahudhanapati, Jiangning Tan, Daniel J Kass, Yingze Zhang

This review article explores the relaxin hormone and its receptor, RXFP1, a signaling pathway known for its ability to soften ligaments and connective tissue. While relaxin shows potent antifibrotic potential in laborat…

RXFP1; alternative splicing; fibrosis; relaxin.
A+++2020

A Closer Look at Anandamide Interaction With TRPV1

Chante Muller, Diane L Lynch, Dow P Hurst, Patricia H Reggio

This study used advanced molecular dynamics simulations to investigate how anandamide, an endocannabinoid, interacts with the TRPV1 ion channel, which is central to pain perception. The researchers observed that anandam…

TRP channels; TRPV1; anandamide; cannabinoids; molecular dynamics
A+2020

Recent advances in the anti-aging effects of phytoestrogens on collagen, water content, and oxidative stress

Tao Liu, Nan Li, Yi-Qi Yan, Yan Liu, Ke Xiong, Yang Liu, Qing-Mei Xia, Han Zhang, Zhi-Dong Liu

This narrative review examines how phytoestrogens, plant-derived compounds that mimic human estrogen, may influence skin aging processes. Research suggests these molecules can help counteract the decline in collagen and…

collagen; estrogen; oxidative stress; phytoestrogens; skin aging; water content
A+2020

Narrative review of the epidemiology, diagnosis and pathophysiology of pelvic organ prolapse

Adi Y Weintraub, Hannah Glinter, Naama Marcus-Braun

This narrative review examines the epidemiology and causes of pelvic organ prolapse (POP), a condition affecting many women's quality of life. The authors highlight a discrepancy in prevalence rates, noting that while a…

Epidemiology; Pelvic Organ Prolapse; physiopathology
A++2020

Higher Circulating Cortisol in the Follicular vs. Luteal Phase of the Menstrual Cycle: A Meta-Analysis

Ajna Hamidovic, Kristina Karapetyan, Fadila Serdarevic, So Hee Choi, Tory Eisenlohr-Moul, Graziano Pinna

This meta-analysis investigated how levels of the stress hormone cortisol vary across the menstrual cycle in healthy women. By synthesizing data from multiple high-quality studies, researchers found that cortisol levels…

cortisol; follicular; hypothalamic-pituitary-adrenal (HPA) axis; hypothalamic-pituitary-gonadal (HPG) axis; luteal; menstrual cycle
A++2020

Biotensegrity: What is the big deal?

Graham Scarr

Details for this entry have not yet been summarized. The title, "Biotensegrity: What is the big deal?", suggests it is an explanatory or editorial piece about the concept of biotensegrity. Biotensegrity is a model that…

biotensegrity
A+2020

The Rolf Method of Structural Integration and Pelvic Floor Muscle Facilitation: Preliminary Results of a Randomized, Interventional Study

Martyna Kasper-Jedrzejewska, Grzegorz Jedrzejewski, Lucyna Ptaszkowska, Kuba Ptaszkowski, Robert Schleip, Tomasz Halski

This randomized, interventional study investigated how the Rolf Method of Structural Integration (SI) affects pelvic floor muscle function in healthy women. Thirty-three women were divided into two groups; one received…

pelvic floor muscles; Structural Integration; surface electromyography
A+++2020

Collagen supplementation for skin health: A mechanistic systematic review

Meisam Barati, Masoumeh Jabbari, Roya Navekar, Fariba Farahmand, Reihaneh Zeinalian, Ammar Salehi-Sahlabadi, Nasrin Abb…

This systematic review evaluates the impact of collagen supplementation on skin health and aging parameters. By analyzing ten clinical trials, researchers found that oral intake of both intact and hydrolyzed collagen co…

M2-like macrophage; collagen; collagen hydrolysate; oral tolerance; regulatory T cell; skin health.