Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2020
Manipulation of the Fascial System Applied During Acute Inflammation of the Connective Tissue of the Thoracolumbar Region Affects Transforming Growth Factor-β1 and Interleukin-4 Levels: Experimental Study in Mice
Maria Elisa Duarte França, Larissa Sinhorim, Daniel Fernandes Martins, Robert Schleip, Nicolas A M M Machado-Pereira, G…This animal study investigated the effects of manual fascial manipulation on acute inflammation in the connective tissue of mice's lower backs. Researchers induced inflammation and then applied a specific manipulation p…
inflammationcytokinesfascial systemManipulationmice - A2020
Reflections on the Development of Fascial Tissue: Starting from Embryology
Bruno Bordoni, Bruno MorabitoThis reflective article discusses the ongoing challenges in classifying fascial tissue. The authors highlight that the scientific literature contains many contradictions and lacks a clear, straightforward definition. Th…
fasciaMyofascialSurgeryAnatomyembryology - A2020
Acute Effects of Dynamic Stretching Followed by Vibration Foam Rolling on Sports Performance of Badminton Athlets
W-C Lin, C-L Lee, N-J ChangThis study investigated the effects of two different warm-up routines on the performance of badminton athletes. Researchers compared dynamic stretching (DS) alone to a combination of dynamic stretching followed by vibra…
vibration therapyFoam rollingWarm up exerciseathletic performancesports - A++2020
Effect of Low-Intensity Vibration on Bone Strength, Microstructure, and Adiposity in Pre-Osteoporotic Postmenopausal Women: A Randomized Placebo-Controlled Trial
Chamith S Rajapakse, Alyssa J Johncola, Alexandra S Batzdorf, Brandon C Jones, Mona Al Mukaddam, Kelly Sexton, Justine…This randomized, placebo-controlled trial investigated if daily low-intensity vibration could improve bone health in postmenopausal women with pre-osteoporosis. For one year, one group used a vibrating platform for 10 m…
VIBRATION THERAPY; BONE; OSTEOPOROSIS; MRI - A+++2020
Mini-Review on the Roles of Vitamin C, Vitamin D, and Selenium in the Immune System against COVID-19
Minkyung Bae, Hyeyoung KimThis mini-review discusses how vitamin C, vitamin D, and selenium may affect the immune system in relation to COVID-19. Research suggests that deficiencies in these micronutrients are common in patients with acute respi…
COVID-19; infectious disease; selenium; virus; vitamin C; vitamin D - A+++2020
Low-frequency mechanical vibration induces apoptosis of A431 epidermoid carcinoma cells
Wresti L Anggayasti, Chikahiro Imashiro, Taiki Kuribara, Kiichiro Totani, Kenjiro TakemuraResearchers are exploring mechanical vibration as a potential cancer therapy that avoids harming healthy cells. In this lab study, a brief, low-frequency vibration was applied to a line of human skin cancer cells (A431)…
apoptosismechanical vibrationcancer cell modelglucose metabolismhigh-mobility group box 1 - A2020
Calf stretching and plantar fascia-specific stretching for plantar fasciitis: A systematic review and meta-analysis
Akkradate Siriphorn, Sukanya EksakulklaThis systematic review and meta-analysis looked at eight studies to compare two common stretching techniques for plantar fasciitis: calf stretching and plantar fascia-specific stretching. The authors analyzed the data t…
Achilles stretching; Calf stretching; Plantar fascia-specific stretching; Plantar fasciitis; Tendon. - A2020
Day of peak pain reduction by a single session of dry needling in the upper trapezius myofascial trigger points: A 14 daily follow-up study
Phichamon Khanittanuphong, Phichaporn UphoThis study tracked daily pain in people with upper trapezius trigger points following a single dry needling session. Participants received one treatment combined with self-stretching exercises and reported their pain fo…
Dry needling; Myofascial trigger points; Pain; Upper trapezius muscle. - A2020
Iliopsoas muscle thickness and pelvic alignment in pronated and normal foot postures
Zinat Ashnagar, Mohammad-Reza Hadian, Gholamreza Olyaei, Saeed Talebian, Asghar Rezasoltani, Hassan Saeedi, Mir Saeed Y…This study investigated whether chronic foot hyperpronation is linked to changes in pelvic alignment and iliopsoas muscle thickness. Researchers compared a group of women with pronated feet to a group with normal foot p…
Hyperpronation; Iliopsoas; Pelvic angle; Ultrasound imaging. - B2020
Morphological and immunophenotypic characterization of perivascular interstitial cells in human glioma: Telocytes, pericytes, and mixed immunophenotypes
Lubov Mitrofanova, Anton Hazratov, Boris Galkovsky, Andrey Gorshkov, Danila Bobkov, Dmitry Gulyaev, Evgeny ShlyakhtoResearchers investigated two types of cells, telocytes and pericytes, found around blood vessels in brain tumors. The study found that the number of telocytes was ten times higher in the more aggressive glioblastoma tum…
telocytes; pericytes; confocal microscopy; primary culture of glioma telocytes; glioblastoma - A+++2020
Continuous Ascorbate Infusions in the Management of Patients with Advanced Colon Cancer
Nina MikirovaThis study analyzed data from a previous clinical trial involving 17 patients with late-stage colon cancer. The patients received continuous intravenous infusions of vitamin C (ascorbate) over 6-8 weeks. Researchers fou…
Vitamin CAscorbic acidcolon cancer - A++2020
Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections
Philip C Calder, Anitra C Carr, Adrian F Gombart, Manfred EggersdorferIn this review, the authors state that optimal nutritional status is crucial for a well-functioning immune system and protection against viral infections. They highlight that many vitamins (A, B6, B12, C, D, E, folate),…
immune system; viral infection; influenza; COVID-19; micronutrients; vitamins; omega-3 fatty acids; minerals; vitamin C; vitamin D