Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesApplications and Emerging Trends of Hyaluronic Acid in Tissue Engineering, as a Dermal Filler, and in Osteoarthritis Treatment
This narrative review summarizes knowledge about hyaluronic acid (HA), a naturally occurring polymer found in the body's connective tissues and fluids. The authors describe how HA contributes to the structural propertie…
Earthing (Grounding) the Human Body Reduces Blood Viscosity—a Major Factor in Cardiovascular Disease
This small study investigated how direct physical contact with the earth, known as 'grounding' or 'earthing', affects blood properties. Ten healthy participants were grounded for two hours using conductive patches on th…
Implementation of Matrix Rhythm Therapy and Conventional Massage in Young Females and Comparison of Their Acute Effects on Circulation
This randomized controlled trial compared the acute effects of Matrix Rhythm Therapy and conventional massage on lower leg blood circulation in young, healthy women. Fifteen participants received a single 30-minute sess…
Purine receptor mediated actin cytoskeleton remodeling of human fibroblasts
This laboratory study investigated how certain molecules, called purines, affect human fibroblast cells. Previous research has shown that acupuncture can trigger the release of purines like ATP. The researchers exposed…
Histological analysis of the rectus capitis posterior major’s myodural bridge
This cadaver study investigated a small tissue bridge between a suboccipital muscle (rectus capitis posterior major) and the dura mater, the protective covering of the spinal cord. Using microscopic analysis on tissue f…
Anatomic connections of the diaphragm: influence of respiration on the body system
This review article explains why the diaphragm muscle is a critical crossroads of information for the entire body. The authors describe its extensive anatomical, fascial, and neurological connections, which link it to s…
What Lies Beneath: Sub-Articular Long Bone Shape Scaling in Eutherian Mammals and Saurischian Dinosaurs Suggests Different Locomotor Adaptations for Gigantism
This study explored why giant dinosaurs were more common than giant mammals by examining their joint structures. Researchers compared the long bones of large mammals like elephants and rhinos with those of saurischian d…
Of Mice, Men and Elephants: The Relation between Articular Cartilage Thickness and Body Mass
This study investigated how articular cartilage adapts to body size across different mammals. Researchers analyzed cartilage from the knee joints of 58 species, ranging from mice to elephants. They found that while cart…
Squeeze film lubrication for non-Newtonian fluids with application to manual medicine
Researchers used a mathematical model to investigate how manual therapy affects the fluid in and around fascia. The model focused on hyaluronic acid (HA), a natural lubricant in connective tissue. The results suggest th…
Nociception originating from the crural fascia in rats
This animal study investigated how the crural fascia, the connective tissue around the lower leg muscles, might be a source of pain signals in rats. Researchers found that this fascia is densely populated with nerve fib…
Fascial Components of the Myofascial Pain Syndrome
Myofascial pain syndrome (MPS) involves muscle pain and other symptoms linked to trigger points, but the role of fascia is often overlooked. This review summarizes recent research into the biology of fascia to better un…
Metabolic control of hyaluronan synthases
This narrative review explores how a cell's energy and nutritional status regulate the production of hyaluronan (HA), a key component of the extracellular matrix. HA is synthesized by enzymes called HAS, which require s…