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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 1–12 of 24 studies · page 1/2Connective tissueAWith summary
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  1. A
    2018

    New Proposal to Define the Fascial System

    Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Roberto Castagna, Beatrice Sacconi, Paul Mazzucco

    In this proposal, the authors suggest a new definition for the fascial system, noting that a universally accepted one does not yet exist. They argue for including the epidermis (the outer layer of skin) based on functio…

    fasciaConnective tissuefibroblastMyofascialSkin
  2. A
    2018

    The myodural bridge in the common rock pigeon (Columbia livia): Morphology and possible physiological implications

    Chukwuemeka Samuel Okoye, Nan Zheng, Sheng-Bo Yu, Hong-Jin Sui

    In this anatomical study on pigeons, researchers investigated a connective tissue structure called the myodural bridge. Through dissections and tissue analysis of the suboccipital region where the skull meets the neck,…

    Connective tissuecerebrospinal fluiddura materbirdhistological sections
  3. A
    2016

    Human Recombinant Hyaluronidase Injections For Upper Limb Muscle Stiffness in Individuals With Cerebral Injury: A Case Series

    Preeti Raghavan, Ying Lu, Mona Mirchandani, Antonio Stecco

    This case series investigated injections of the enzyme hyaluronidase to treat upper limb muscle stiffness in 20 individuals with cerebral injury. The researchers hypothesized that an accumulation of hyaluronan in the mu…

    fasciaConnective tissueStrokeHypertoniaspasticity
  4. A
    2016

    A Systematic Review of the Soft-Tissue Connections Between Neck Muscles and Dura Mater

    Luis Palomeque-del-Cerro, Luis A Arráez-Aybar, Cleofás Rodriguez-Blanco, Rafael Guzmán-Garcia, Mar Menendez-Aparicio, Á…

    In this systematic review, researchers compiled data from 26 studies to investigate direct soft-tissue connections between neck muscles and the dura mater, the outermost membrane surrounding the spinal cord. The analysi…

    fasciaConnective tissueproprioceptionSpineAnatomy
  5. A
    2014

    Fascia—Current knowledge and future directions in physiatry: Narrative review

    E H Kwong, T W Findley

    In this 2014 narrative review, the authors discuss fascia from the perspective of physiatry, or rehabilitation medicine. They note that while fascia is part of the body's connective tissue, its definition is unclear in…

    fasciaHyaluronic acidConnective tissuefibroblastmechanotransduction
  6. A
    2013

    Cellulite's aetiology: a review

    M de la Casa Almeida, Suarez Serrano, J Rebollo Roldán, J J Jiménez Rejano

    In this literature review, researchers examined the underlying causes of cellulite. They found that cellulite is a complex phenomenon with many interacting factors, rather than a single cause. The research points to wom…

    Connective tissuecellulites
  7. A
    2013

    Cellular Control of Connective Tissue Matrix Tension

    H M Langevin, M Nedergaard, A Howe

    This review article explores how fibroblasts, the cells within connective tissue, actively help regulate tissue tension. Traditionally, the mechanical properties of connective tissue have been attributed to its passive…

    Connective tissuefibroblastmechanicalatpcytoskeleton
  8. A
    2011

    Dynamic fascial release and the role of mechanical/vibrational assist devices in manual therapies

    Zachary Comeaux

    This review article explores the use of mechanical vibration devices in manual therapy. The author examines several such tools, including percussion vibrators, vibrational platforms, and deep tissue oscillation. The art…

    fasciaConnective tissuevibrationpercussion vibrationtonic vibratory reflex
  9. A
    2011

    Pandiculation: Nature’s way of maintaining the functional integrity of the myofascial system?

    Luiz Fernando Bertolucci

    This paper explores the hypothesis that pandiculation—the involuntary stretching and yawning most animals do upon waking—serves a key role for the locomotor system. Beyond preparing the nervous system for wakefulness, t…

    fasciaConnective tissuemyofasciayawningsleep-wake rhythm
  10. A
    2011

    Sensory Innervation of the Nonspecialized Connective Tissues in the Low Back of the Rat

    Sarah M Corey, Margaret A Vizzard, Gary J Badger, Helene M Langevin

    In this animal study, researchers investigated the sensory nerves in the nonspecialized connective tissue of the rat low back, an area where knowledge is limited. Using 3D reconstruction and dye-labeling techniques, the…

    fasciaConnective tissueinnervationlow back painmusculoskeletal pain
  11. A
    2011

    Fibroblast cytoskeletal remodeling contributes to connective tissue tension

    H M Langevin, N A Bouffard, J R Fox, B M Palmer, J Wu, J C Iatridis, W D Barnes, G J Badger, A K Howe

    The mechanical properties of connective tissue, such as its elasticity and resistance, have traditionally been attributed to its non-cellular matrix. This study investigated the role of fibroblasts, the cells residing w…

    fasciaConnective tissuefibroblastcytoskeletal remodeling
  12. A
    2010

    Edema and fluid dynamics in connective tissue remodelling

    Rolf K Reed, Åsa Lidén, Kristofer Rubin

    This review describes the role of loose connective tissues, focusing on fluid exchange across capillaries and the formation of edema (swelling). This process is relevant for conditions like inflammation, fibrosis (scarr…

    inflammationLoose connective tissueConnective tissueheartEdema