Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2014
Clinical Relevance of Fascial Tissue and Dysfunctions
Werner Klingler, M Velders, K Hoppe, M Pedro, Robert SchleipFascia is a continuous network of connective tissue that supports the entire body. Traditionally seen as a passive structure, recent research shows it plays a more active role. Fascia contains contractile elements that…
fasciaMyofascial painlumbar fasciadysfunction - A2014
Mechanotransduction and extracellular matrix homeostasis
Jay D Humphrey, Eric R Dufresne, Martin A SchwartzConnective tissues are dynamic, constantly adapting even at rest. Cells within these tissues continually sense mechanical cues from their environment through a process called mechanotransduction. In response, they maint…
fasciaextracellular matrixIntegrinsmechanosensingmechanoregulation - A2014
Biotensegrity of the extracellular matrix: physiology, dynamic mechanical balance, and implications in oncology and mechanotherapy
Irene Tadeo, Ana P Berbegall, Luis M Escudero,Tomás Álvaro, Rosa NogueraThis 2014 review article explores the concept of biotensegrity, a principle where cells and tissues maintain structural integrity through a balance of tension and compression. This dynamic mechanical balance involves th…
fasciaextracellular matrixcancerbiotensegritymechanotherapy - A2014
Lumbopelvic muscle activation patterns in three stances under graded loading conditions: Proposing a tensegrity model for load transfer through the sacroiliac joints
Hamed Pardehshenas, Nader Maroufi, Mohammad Ali Sanjari, Mohamad Parnianpour, Stephen M LevinResearchers investigated how lumbopelvic muscles activate to stabilize the sacroiliac (SI) joints under different loads. They compared muscle activity in 30 men during two-legged and one-legged standing while holding we…
fasciasacroiliac jointload transferwire-spoke wheel modelarch theory; Self-bracing - A2014
Definition of the To Be Named Ligament and Vertebrodural Ligament and Their Possible Effects on the Circulation of CSF
Nan Zheng, Xiao-Ying Yuan, Yun-Fei Li, Yan-Yan Chi, Hai-Bin Gao, Xin Zhao, Sheng-Bo Yu, Hong-Jin Sui, John SharkeyIn this cadaver study, researchers investigated connective tissue structures in the upper neck of 30 human specimens. They identified two specific ligaments, the 'to be named ligament' (TBNL) and the vertebrodural ligam…
fasciadura materMyodural Bridgecerebrospinal fluid circulation - A2013
A pilot study of myofascial release therapy compared to Swedish massage in Fibromyalgia
Ginevra Liptan, Scott Mist, Cheryl Wright, Anna Arzt, Kim Dupree JonesThis small pilot study compared the effects of myofascial release (MFR) and Swedish massage on women with fibromyalgia. Participants received either MFR or Swedish massage for 90 minutes weekly over four weeks. While bo…
fasciaMyofascial releaseFibromyalgiamassage therapycentral sensitization - A2013
Purine receptor mediated actin cytoskeleton remodeling of human fibroblasts
Nanna Goldman, Devin Chandler-Militello, Helene Langevin, Maiken Nedergaard, Takahiro TakanoThis laboratory study investigated how certain molecules, called purines, affect human fibroblast cells. Previous research has shown that acupuncture can trigger the release of purines like ATP. The researchers exposed…
fasciacytoskeletonacupunctureFibroblastscalcium signaling - A2013
Histological examination of the human obliquus capitis inferior myodural bridge
Matthew E Pontella, Frank Scali, Dennis E Enix, Patrick J Battaglia, Ewarld MarshallThis cadaver study examined the connection between a deep neck muscle, the obliquus capitis inferior (OCI), and the dura mater, the tough outer layer covering the spinal cord. Researchers dissected tissue from eight cad…
fasciacervical spineMyodural Bridgeobliquus capitis inferiordura - A2013
Histological analysis of the rectus capitis posterior major’s myodural bridge
Frank Scali, Matthew E Pontell, Dennis E Enix, Ewarld MarshallThis cadaver study investigated a small tissue bridge between a suboccipital muscle (rectus capitis posterior major) and the dura mater, the protective covering of the spinal cord. Using microscopic analysis on tissue f…
fasciacervical spinerectus capitis posterior majorMyodural Bridgecervical dura mater - A2013
Anatomic connections of the diaphragm: influence of respiration on the body system
Bruno Bordoni, Emiliano ZanierThis review article explains why the diaphragm muscle is a critical crossroads of information for the entire body. The authors describe its extensive anatomical, fascial, and neurological connections, which link it to s…
fasciadiaphragmPelvisphrenic nervevagus nerve - A2013
Hyaluronan: A Simple Polysaccharide with Diverse Biological Functions
Kevin T Dicker, Lisa A Gurski, Swati Pradhan-Bhatt, Robert L Witt, Mary C Farach-Carson, Xinqiao JiaThis review paper describes hyaluronan (HA), a simple sugar molecule found abundantly throughout the body's connective tissues. Despite its simple structure, HA has a surprising array of biological functions. It helps o…
hyaluronanfasciawound healingsynthasehyaluronidase - A2013
Earthing (Grounding) the Human Body Reduces Blood Viscosity—a Major Factor in Cardiovascular Disease
Gaétan Chevalier, Stephen T Sinatra, James L Oschman, Richard M DelanyThis small study investigated how direct physical contact with the earth, known as 'grounding' or 'earthing', affects blood properties. Ten healthy participants were grounded for two hours using conductive patches on th…
fasciaearthinggroundingearth surface electronscardiovasclar disease
