Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

with plain-language summary

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Showing 37–48 of 427 studies · page 4/36A With summary

A
2020
Iliopsoas muscle thickness and pelvic alignment in pronated and normal foot postures
Zinat Ashnagar, Mohammad-Reza Hadian, Gholamreza Olyaei, Saeed Talebian, Asghar Rezasoltani, Hassan Saeedi, Mir Saeed Y…
This study investigated whether chronic foot hyperpronation is linked to changes in pelvic alignment and iliopsoas muscle thickness. Researchers compared a group of women with pronated feet to a group with normal foot p…
Hyperpronation; Iliopsoas; Pelvic angle; Ultrasound imaging.
A
2020
The relaxin family peptide receptor 1 (RXFP1): An emerging player in human health and disease
Ting-Yun Chen, Xiaoyun Li, Ching-Hsia Hung, Harinath Bahudhanapati, Jiangning Tan, Daniel J Kass, Yingze Zhang
This review article explores the relaxin hormone and its receptor, RXFP1, a signaling pathway known for its ability to soften ligaments and connective tissue. While relaxin shows potent antifibrotic potential in laborat…
RXFP1; alternative splicing; fibrosis; relaxin.
A
2020
Ageing of the diaphragm muscle
Bruno Bordoni, Bruno Morabito, Marta Simonelli
This narrative review explores how the diaphragm, our main breathing muscle, is affected by aging. Like other muscles, the diaphragm can weaken and lose mass over time, a condition known as sarcopenia. This age-related…
fasciadiaphragmskeletal musclephrenic nervevagus nerve
A
2020
Muscle Cramps
Bruno Bordoni, Kavin Sugumar, Matthew Varacallo
Muscle cramps are involuntary, painful, and localized contractions of a muscle or muscle fibers, often felt as a palpable knot. While common in sports, their exact cause is not fully understood and likely depends on var…
Diagnosiscramp
A
2020
Evaluation of scapular mobilization and comparison to pectoralis minor stretching in individuals with rounded shoulder posture: A randomized controlled trial
Maedeh Fani, Samaneh Ebrahimi, Ali Ghanbari
This randomized controlled trial investigated treatments for rounded shoulder posture in 52 healthy students. Researchers compared the effects of scapular mobilization, pectoralis minor self-stretching, and a combinatio…
Mobilization; Pectoralis minor stretching; Rounded shoulder; Scapular kinematics.
A
2020
Virtual reality in the rehabilitation process for individuals with cerebral palsy and Down syndrome: A systematic review
Jamile Benite Palma Lopes, Natalia de Almeida Carvalho Duarte, Roberta Delasta Lazzari, Claudia Santos Oliveira
This systematic review compiled research on virtual reality (VR) as a rehabilitation tool for children with cerebral palsy and Down syndrome. Researchers analyzed five high-quality studies and found that VR training, bo…
Cerebral palsy; Down syndrome; Movement analysis; Virtual reality.
A
2019
Ultrasound Imaging of the Fascial Layers
Carmelo Pirri, Carla Stecco, Levent Özçakar
This publication, for which a full summary is not yet available, appears to discuss using ultrasound to visualize the body's fascial layers. Ultrasound imaging is a non-invasive technique that provides real-time views o…
ultrasound.fascial layers
A
2019
Active Contractile Properties of Fascia
ROBERT SCHLEIP, WERNER KLINGLER
This narrative review explores how fascia, often seen as a passive tissue, can actively contract. Researchers point to the presence of cells called myofibroblasts within the fascia, which give it the ability to change i…
myofibroblast; fascia; connective tissue; contracture; stiffness; fibrosis
A
2019
Glut-1 explains the evolutionary advantage of the loss of endogenous vitamin C-synthesis
Tabea C Hornung, Hans-Konrad Biesalski
Unlike many animals, humans cannot produce their own vitamin C. This study explores a potential evolutionary advantage of this loss. Researchers compared red blood cells from humans and pigs (who can make vitamin C) and…
glucose transporter; vitamin C; gulono-lactone-oxidase; vitamin C recycling
A
2019
Hyaluronan/collagen hydrogels containing sulfated hyaluronan improve wound healing by sustained release of heparin-binding EGF-like growth factor
Stephan Thönes, Sandra Rother, Tom Wippold, Joanna Blaszkiewicz, Kanagasabai Balamurugan, Stephanie Moeller, Gloria Rui…
This study investigated a new type of hydrogel designed to improve wound healing. Researchers combined collagen and hyaluronan (HA), a natural component of connective tissue, with a growth factor that stimulates skin ce…
Biomimetic material; Extracellular matrix (ECM); Fibroblasts; Heparin-binding epidermal growth factor-like growth factor (HB-EGF); Hyaluronan; Hydrogel; Sulfated hyaluronan; Surface plasmon resonance; Wound healing.
A
2019
The diaphragm muscle manual evaluation scale
Bruno Bordoni, Bruno Morabito
This technical report describes a new method for manually assessing the diaphragm's function, called the Manual Evaluation Diaphragm (MED) scale. The scale is designed to generate a value for the respiratory muscle's mo…
fasciaMyofascialdiaphragmSurgeryphrenic nerve
A
2019
Quantifying muscle glycosaminoglycan levels in patients with post-stroke muscle stiffness using T1p MRI
Rajiv G Menon, Preeti Raghavan, Ravinder R Regatte
This study is the first to quantify the amount of hyaluronan, a key component for gliding movements within fascia. Researchers measured hyaluronan in tissue samples from various human anatomical sites and found that the…
hyaluronanStrokestiffnesshyaluronidase