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The Fascia Guide
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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 409–420 of 427 studies · page 35/36AWith summary
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  1. A
    2002

    Relationship of Acupuncture Points and Meridians to Connective Tissue Planes

    Helene M Langevin, Jason A Yandow

    Researchers investigated the hypothesis that the network of acupuncture points and meridians could represent the body's network of interstitial connective tissue. By mapping points in anatomical cross-sections of a huma…

    acupuncture; meridians; connective tissue; anatomy; fascia; signal transduction
  2. A
    2002

    Adhesive capsulitis: role of MR imaging in differential diagnosis

    David Connell, Ravi Padmanabhan, Rachelle Buchbinder

    This study investigated whether magnetic resonance imaging (MRI) can identify the changes typical of adhesive capsulitis (frozen shoulder). Researchers compared MRI scans from 24 patients with clinical evidence of froze…

    frozen shoulderAdhesive capsulitisMR imagingArthroscopy
  3. A
    2002

    Evidence of Connective Tissue Involvement in Acupuncture

    Helene M Langevin, David L Churchill, Junru Wu, Gary J Badger, Jason A Yandow, James R Fox, Martin H Krag

    Researchers investigated the "needle grasp" phenomenon in acupuncture, where it becomes harder to pull a needle out after manipulation. They hypothesized this is caused by connective tissue winding around the needle, ra…

    mechanical stressSubcutaneous tissueultrasound.Biomechanicshistology
  4. A
    2001

    Mechanical signaling through connective tissue: a mechanism for the therapeutic effect of acupuncture

    Helene M Langevin, David L Churchill, Marilyn J Cipolla

    This paper proposes a hypothesis for how acupuncture might work. The authors focus on the "de qi" sensation, which includes the acupuncturist feeling a "needle grasp" in the tissue. They suggest that when an acupuncture…

    collagenmechanotransductionmeridian
  5. A
    2001

    Hyaluronan and Homeostasis: A Balancing Act

    M I Tammi, A J Day, E A Turley

    As only the title of this paper is available, it has not yet been summarized. The title suggests the article discusses the role of hyaluronan in maintaining homeostasis, the body's state of physiological balance. This i…

    hyaluronan homeostasis
  6. A
    2000

    Effect of Mechanical Load on Articular Cartilage Collagen Structure: A Scanning Electron-Microscopic Study

    Max J Kääb, Keita Ito, Berton Rahn, John M Clark, Hubert P Nötzli

    This study on rabbit knees examined how static mechanical loads affect the collagen structure of articular cartilage. Researchers applied varying levels of force for different durations to simulate muscle activity, then…

    rabbit.Morphology; Loadingmechanical; Collagen fibers; Scanning electron microscopy; Cryofixation; Freeze substitution
  7. A
    2000

    Adhesive Capsulitis

    Jo A Hannafin, Theresa A Chiaia

    In this 2000 review article, the authors examine adhesive capsulitis, or frozen shoulder, a condition of unknown cause that restricts shoulder motion. They review what is known about its etiology and critically evaluate…

    frozen shoulderAdhesive capsulitisstages
  8. A
    1999

    Tensegrity and mechanoregulation: from skeleton to cytoskeleton

    Christopher S Chen, Donald E Ingber

    This review article explores how mechanical forces are transmitted from the whole body down to individual cells. The authors propose that a design principle called "tensegrity," which uses continuous tension and local c…

    extracellular matrixTensegritycytoskeletonmechanotransductionIntegrins
  9. A
    1999

    Oral Administration of 14C Labeled Gelatin Hydrolysate Leads to an Accumulation of Radioactivity in Cartilage of Mice (C57/BL)

    Steffen Oesser, Milan Adam, Wilfried Babel, Jürgen Seifert

    In this animal study, researchers investigated how gelatin hydrolysate is absorbed and distributed in the bodies of mice. Using a radioactive label, they tracked the gelatin after it was administered orally. The results…

    gelatin hydrolysate; peptide absorption; organ distribution; cartilage; mice (C57/BL)
  10. A
    1997

    Tensegrity: The Architectural Basis of Cellular Mechanotransduction

    D E Ingber

    This 1997 review article proposes a model for how cells sense and respond to physical forces, a process called mechanotransduction. The author suggests that cells are built using 'tensegrity' architecture, a system of b…

    extracellular matrixsignal transductioncytoskeletonIntegrinsmechanoreceptor
  11. A
    1996

    Effects of continuous and Intermittent forces on human fibroblasts in vitro

    Aldo Carano, Giuseppe Siciliani

    This in vitro study investigated how human connective tissue cells (fibroblasts) respond to different types of mechanical force. Researchers grew fibroblasts on flexible membranes and subjected them to either continuous…

    fibroblasttissue remodelingmechanical load
  12. A
    1994

    Glutathione-Ascorbic Acid Antioxidant System in Animals

    Alton Meister

    This 1994 publication by Alton Meister discusses the biochemical interaction between glutathione and ascorbic acid (Vitamin C) within animal antioxidant systems. As the source material is limited to the title, the summa…

    Vitamin CAscorbic acidantioxidantanimals