Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2020
The link between vitamin D and COVID-19: distinguishing facts from fiction
P BergmanThis 2020 article, available only by title, appears to be a review or commentary on the relationship between vitamin D and COVID-19. The title, "The link between vitamin D and COVID-19: distinguishing facts from fiction…
COVID-19vitamin D - A2020
Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province
Kui Liu, Yuan-Yuan Fang, Yan Deng, Wei Liu, Mei-Fang Wang, Jing-Ping Ma, Wei Xiao, Ying-Nan Wang, Min-Hua Zhong, Cheng-…This retrospective study analyzed clinical data from 137 patients with the novel coronavirus (2019-nCoV) hospitalized in China's Hubei province during the initial outbreak. The most common initial symptoms were fever, c…
Coronavirus; 2019 Novel coronavirus (2019-nCoV); Clinical characteristics; Treatment; Hubei province - A2020
A Novel Role of Ascorbic Acid in Anti-Inflammatory Pathway and ROS Generation in HEMA Treated Dental Pulp Stem Cells
Francesca Diomede, Guya Diletta Marconi, Simone Guarnieri, Michele D’Attilio, Marcos F X B Cavalcanti, Maria A Mariggiò…Components from common dental resins can sometimes cause inflammation and oxidative stress in the cells of the dental pulp. This laboratory study investigated whether ascorbic acid (Vitamin C) could protect human dental…
human dental pulp stem cells; hema; ascorbic acid; nfkb; erk; perk; inflammatory cytokines - A2020
A new clinical trial to test high-dose vitamin C in patients with COVID-19
Anitra C CarrThis 2020 entry by Anitra C. Carr announces a new clinical trial. The study was designed to investigate the effects of high-dose vitamin C on patients with COVID-19. As this is only a title entry, no details about the s…
Vitamin CCOVID-19corona virushigh-dose C - A2020
Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis
Eric Gracey, Arne Burssens, Isabelle Cambré, Georg Schett, Rik Lories, Iain B. McInnes, Hiroshi Asahara, Dirk ElewautThis review article discusses how mechanical loading affects tendons and ligaments. While normal levels of loading are essential for maintaining tissue health, pathological levels of force act as a stressor that can tri…
mechanical stressMechanical loadingtendonrepair of tissueligament - A2020
Feeling Things Out: Bidirectional Signaling of the Cell–ECM Interface, Implications in the Mechanobiology of Cell Spreading, Migration, Proliferation, and Differentiation
Andrew E Miller, Ping Hu, Thomas H BarkerThis narrative review describes how cells and their surrounding environment, the extracellular matrix (ECM), constantly communicate with each other. This communication involves physical cues from the ECM being translate…
extracellular matrixstiffnesscytoskeletonmechanotransduction - A2020
Symptomatology correlations between the diaphragm and irritable bowel syndrome
Bruno Bordoni, Bruno MorabitoThis narrative review explores the potential connection between the diaphragm muscle and Irritable Bowel Syndrome (IBS). The authors propose that an altered contractile ability of the diaphragm and different breathing p…
painlow back paindiaphragmirritable bowel syndromechronic headache - A2020
T1ρ‐Mapping for Musculoskeletal Pain Diagnosis: Case Series of Variation of Water Bound Glycosaminoglycans Quantification before and after Fascial Manipulation® in Subjects with Elbow Pain
Rajiv G Menon, Stephen F Oswald, Preeti Raghavan, Ravinder R Regatte, Antonio SteccoIn this small case series, researchers evaluated five patients with chronic elbow pain. Using an advanced MRI technique (T1ρ-mapping), they measured the concentration of bound and unbound water in the deep fascia before…
T1ρ; fascial manipulation; epicondylitis - A2020
A randomized clinical trial for the effect of static stretching and strengthening exercise on pelvic tilt angle in LBP patients
Mohammad Bagher Shamsi, Soodeh Shahsavari, Ameneh Safari, Maryam MirzaeiThis randomized clinical trial investigated whether stretching or strengthening tight hamstrings could change pelvic posture in people with low back pain. Forty-five participants were divided into three groups: static s…
low back painPelvic tiltHamstring - A2020
Identification of Telocytes in the Pancreas of Turtles—A role in Cellular Communication
Noor Samad Gandahi, Botao Ding, Yonghong Shi, Xuebing Bai, Jameel Ahmed Gandahi, Waseem Ali Vistro, Qiusheng Chen, Ping…In this animal study, researchers examined the pancreas of turtles to look for a specific cell type called telocytes. Using advanced microscopy and other laboratory techniques, they confirmed for the first time that the…
cellular communication; exosomes; pancreas; soft-shelled turtle; telocytes; telopodes. - A2020
Calf stretching and plantar fascia-specific stretching for plantar fasciitis: A systematic review and meta-analysis
Akkradate Siriphorn, Sukanya EksakulklaThis systematic review and meta-analysis looked at eight studies to compare two common stretching techniques for plantar fasciitis: calf stretching and plantar fascia-specific stretching. The authors analyzed the data t…
Achilles stretching; Calf stretching; Plantar fascia-specific stretching; Plantar fasciitis; Tendon. - A2020
Day of peak pain reduction by a single session of dry needling in the upper trapezius myofascial trigger points: A 14 daily follow-up study
Phichamon Khanittanuphong, Phichaporn UphoThis study tracked daily pain in people with upper trapezius trigger points following a single dry needling session. Participants received one treatment combined with self-stretching exercises and reported their pain fo…
Dry needling; Myofascial trigger points; Pain; Upper trapezius muscle.