Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2020
Anatomy, Head and Neck, Anterior Vagus Nerve
Maximo Baquiran, Bruno BordoniThis article is an anatomical description of the anterior vagus nerve in the head and neck. As only the title is available, the content has not yet been summarized in detail. The title suggests the text provides an over…
Anatomyvagus nervecranial nerve - A2020
Role of fascial connectivity in musculoskeletal dysfunctions: A narrative review
M S Ajimsha, Pramod D Shenoy, Neeraj GampawarThis narrative review examines the concept of "fascial connectivity," which suggests that muscles and fascia are linked in functional chains throughout the body. The authors analyzed 35 studies, including cadaveric, ani…
Fascia; Fascial connectivity; Myofascial chains; Myofascial meridians. - A2020
PIEZO2: A Novel Molecule Involved in the Development of AIS
Zhichong Wu, Yuwen Wang, Chao Xia, Zhenhua Feng, Yong Qiu, Jack Chun-Yiu Cheng, Leilei Xu, Zezhang ZhuThis case-control study investigated the potential link between the PIEZO2 gene, proprioception (the body's sense of position), and adolescent idiopathic scoliosis (AIS). Researchers found that AIS patients often exhibi…
proprioceptionpiezo2AIS - A2020
Pilates exercise improves the clinical and immunological pro!les of patients with human T-cell lymphotropic virus 1 associated myelopathy: A pilot study
Altair Vallinoto Klautau, Denise da Silva Pinto, Bárbara Brasil Santana, Maria Alice Freitas Queiroz, Andréa Nazar!e M…This pilot study investigated the effects of a 10-week Pilates program for eight patients with the chronic inflammatory disease HAM/TSP. After the exercise period, participants experienced significant improvements in pa…
cytokinesHTLV-1HTLV-1-Associated myelopathyPilates - A2020
Quantitative analysis of gliding between subcutaneous tissue and the vastus lateralis - Influence of the dense connective tissue of the myofascia
Kengo Kawanishi, Shintarou KudoThis study investigated the relationship between the thickness of connective tissue layers and their ability to glide past one another. Using ultrasound, researchers observed the vastus lateralis muscle on the outer thi…
Connective tissue; GLIDING; Particle image velocimetry. - A2020
A Hyaluronan-binding Peptide (P15-1) Reduces inflammatory and catabolic events in IL-1beta-treated human articular chondrocytes
Claire Shortt, Leonard G Luyt, Eva A Turley, Mary K Cowman, Thorsten KirschInflammation in osteoarthritis drives cartilage degradation. In this laboratory study, researchers investigated whether a peptide (P15-1) combined with hyaluronan (HA) could protect human cartilage cells in a simulated…
hyaluronaninflammationchondrocytesP15-1IL-1beta - A2020
The link between vitamin D and COVID-19: distinguishing facts from fiction
P BergmanThis 2020 article, available only by title, appears to be a review or commentary on the relationship between vitamin D and COVID-19. The title, "The link between vitamin D and COVID-19: distinguishing facts from fiction…
COVID-19vitamin D - A2020
Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province
Kui Liu, Yuan-Yuan Fang, Yan Deng, Wei Liu, Mei-Fang Wang, Jing-Ping Ma, Wei Xiao, Ying-Nan Wang, Min-Hua Zhong, Cheng-…This retrospective study analyzed clinical data from 137 patients with the novel coronavirus (2019-nCoV) hospitalized in China's Hubei province during the initial outbreak. The most common initial symptoms were fever, c…
Coronavirus; 2019 Novel coronavirus (2019-nCoV); Clinical characteristics; Treatment; Hubei province - A2020
A Novel Role of Ascorbic Acid in Anti-Inflammatory Pathway and ROS Generation in HEMA Treated Dental Pulp Stem Cells
Francesca Diomede, Guya Diletta Marconi, Simone Guarnieri, Michele D’Attilio, Marcos F X B Cavalcanti, Maria A Mariggiò…Components from common dental resins can sometimes cause inflammation and oxidative stress in the cells of the dental pulp. This laboratory study investigated whether ascorbic acid (Vitamin C) could protect human dental…
human dental pulp stem cells; hema; ascorbic acid; nfkb; erk; perk; inflammatory cytokines - A2020
A new clinical trial to test high-dose vitamin C in patients with COVID-19
Anitra C CarrThis 2020 entry by Anitra C. Carr announces a new clinical trial. The study was designed to investigate the effects of high-dose vitamin C on patients with COVID-19. As this is only a title entry, no details about the s…
Vitamin CCOVID-19corona virushigh-dose C - A2020
Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis
Eric Gracey, Arne Burssens, Isabelle Cambré, Georg Schett, Rik Lories, Iain B. McInnes, Hiroshi Asahara, Dirk ElewautThis review article discusses how mechanical loading affects tendons and ligaments. While normal levels of loading are essential for maintaining tissue health, pathological levels of force act as a stressor that can tri…
mechanical stressMechanical loadingtendonrepair of tissueligament - A2020
Feeling Things Out: Bidirectional Signaling of the Cell–ECM Interface, Implications in the Mechanobiology of Cell Spreading, Migration, Proliferation, and Differentiation
Andrew E Miller, Ping Hu, Thomas H BarkerThis narrative review describes how cells and their surrounding environment, the extracellular matrix (ECM), constantly communicate with each other. This communication involves physical cues from the ECM being translate…
extracellular matrixstiffnesscytoskeletonmechanotransduction