Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2018
Metabolic acidosis and the role of unmeasured anions in critical illness and injury
Tobias Zingg, Bishwajit Bhattacharya, Linda L MaerzIn this review article, the authors discuss metabolic acidosis, a common condition in critically ill patients that is associated with increased mortality. A significant component of this acidosis can be caused by so-cal…
Metabolic acidosisUnmeasured anionsStrong ion differenceStrong ion gapAnion gap Base excess - A2018
Frontiers in fascia research
Carla Alessandra Avila Gonzalez, Mark Driscoll, Robert Schleip, Scott Wearing, Eric Jacobson, Thomas Findley, Werner Kl…This article reviews recent developments in fascia research, emphasizing new ways to assess this highly variable tissue. Researchers note that fascia differs greatly between individuals in density, stiffness, and metabo…
fasciaultrasound.Pain therapySport sciencesIndentometry - A2018
Fascial well-being: Mechanotransduction in manual and movement therapies
Leon ChaitowThis article discusses mechanotransduction, the process by which cells in connective tissue sense and respond to mechanical forces like stretch, compression, and shear. Specialized cells such as fibroblasts communicate…
mechanotransduction - A2018
Mineralization can be an incidental ultrasonographic finding in equine tendons and ligaments
Etienne J O O'Brien, Roger K W SmithIn this observational study on horses, researchers investigated the presence of mineralization, or calcium deposits, in tendons and ligaments using ultrasound. They found it was most common in the deep digital flexor te…
horsecalcificationDopplerossification - A2018
Variations in Contents of Hyaluronan in the Peritumoral Micro-Environment of Human Chondrosarcoma
Caterina Fede, Carla Stecco, Andrea Angelini, Chenglei Fan, Elisa Belluzzi, Assunta Pozzuoli, Pietro Ruggieri, Raffaele…The micro-environment surrounding a tumor greatly influences its growth and response to therapy. This study focused on chondrosarcoma, a type of bone cancer resistant to both chemotherapy and radiation. Researchers quan…
hyaluronan; chondrosarcoma; peritumoral stroma; fascia; tumor micro-environment; malignant bone tumor; grade - A2018
Not merely a protective packing organ? A review of fascia and its force transmission capacity
Jan Wilke, Robert Schleip, Can A Yucesoy, Winfried BanzerThis review article examines fascia's role in transmitting force throughout the body. Traditionally seen as just a "packing" material, research now suggests fascia is an active tissue that connects muscles into a body-w…
epimuscular; fascia; force transmission; myofascial chains - A2018
Lipedema—An update
Uwe WollinaThis review provides an update on lipedema, a chronic condition affecting subcutaneous fat tissue in the limbs, almost exclusively in women. It typically appears during or after puberty and is characterized by symmetric…
painEdemaobesitylipedemalymphedema - A2018
A review of the impact of pregnancy and childbirth on pelvic floor function as assessed by objective measurement techniques
Hans Van Geelen, Donald Ostergard, Peter SandThis narrative review examines how pregnancy and childbirth affect the pelvic floor, based on studies using objective measurement tools like ultrasound and MRI. The authors found that pregnancy, particularly the first,…
Pregnancy . Childbirth . Vaginal delivery . Cesarean delivery . Pelvic floor function . Objective measurement techniques - A2018
Hyaluronan in adipogenesis, adipose tissue physiology and systemic metabolism
Yi Zhu, llja L Kruglikov, Yucel Akgul, Philipp E SchererThis narrative review summarizes research on hyaluronic acid (HA), a sugar molecule abundant in the body's extracellular matrix. The functions of HA are largely dictated by its molecular size, and it is commonly used as…
HA - A2018
Effectiveness of 3-dimensional shoulder ultrasound in the diagnosis of rotator cuff tears
Aiping Teng, Fanxiao Liu, Dongsheng Zhou, Tao He, Yan Chevalier, Roland M KlarIn this meta-analysis, researchers combined data from seven studies involving 282 patients to evaluate the effectiveness of 3-dimensional (3D) ultrasound in diagnosing rotator cuff tears. The analysis found that 3D ultr…
3-dimensional ultrasounddiagnostic valuemeta-analysisrotator cuff tears - A2018
Orientation and property of fibers of the myodural bridge in humans
Nan Zheng, Yan-Yan Chi, Xiao-Han Yang, Nan-Xing Wang, Yi-Lin Li, Yang-Yang Ge, Lan-Xin Zhang, Tai-Yuan Liu, Xiao-Ying Y…The myodural bridge is a fibrous connection between the deep suboccipital muscles of the neck and the spinal dura mater, the tough outer covering of the spinal cord. In this anatomical study, researchers investigated th…
Atlanto-axial interspace; Atlanto-occipital interspace; Collagen I fibers; Histologic staining; Myodural bridge; Suboccipital muscles; Vertebral dural ligament - A2018
Effectiveness of Physiotherapy Treatment for Urinary Incontinence in Women: A Systematic Review
Remedios López-Liria, María de los Ángeles Varverde-Martínez, David Padilla-Góngora, Patricia Rocamora-PérezThis systematic review evaluated the effectiveness of different physiotherapy techniques for treating urinary incontinence in women. Researchers analyzed 16 studies covering methods such as pelvic floor exercises, vagin…
physiotherapywomenurinary incontinencepelvic floor muscle
