Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

with plain-language summary

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Showing 109–120 of 146 studies · page 10/13fascia A

A
2011
High and Low Molecular Weight Hyaluronic Acid Differentially Regulate Human Fibrocyte Differentiation
A S Maharjan, D Pilling, R H Gomer
Following tissue injury, immune cells called monocytes can differentiate into fibrocytes, a cell type involved in healing and fibrosis. This study investigated how different sizes of hyaluronic acid (HA) affect this pro…
hyaluronanfasciafibrocyte differentiationmonocyte
A
2011
Pandiculation: Nature’s way of maintaining the functional integrity of the myofascial system?
Luiz Fernando Bertolucci
This paper explores the hypothesis that pandiculation—the involuntary stretching and yawning most animals do upon waking—serves a key role for the locomotor system. Beyond preparing the nervous system for wakefulness, t…
fasciaConnective tissuemyofasciayawningsleep-wake rhythm
A
2011
Sensory Innervation of the Thoracolumbar Fascia in Rats and Humans
J Tesarz, U Hoheisel, B Wiedenhöfer, S Mense
This study investigated the nerve supply of the thoracolumbar fascia (TLF), the connective tissue of the low back, in both rats and humans. Researchers found that the fascia is richly innervated with sensory nerves, but…
fasciaNociceptionThoracolumbar fascialow back painimmunohistochemistry
A
2011
Assessing the influence of FDM to the postoperative healing processes in distal fracture of the radius
Tomasz Teszner
Researchers investigated if the Fascial Distortion Model (FDM) could improve recovery following surgery for a common wrist fracture. In this study, 65 patients were divided into two groups; one received standard rehabil…
fasciaManual Therapyfasciaefascial distortion modelreductionism
A
2011
Hyaluronan in intestinal homeostasis and inflammation: implications for fibrosis
Carol A de la Motte
This narrative review explores the role of hyaluronan (HA) in intestinal health and disease. Chronic intestinal inflammation can lead to fibrosis, or scarring, a process driven by inflammatory signals and specialized ce…
hafasciaextracellular matrixfibrosismesenchymal cells
A
2010
How much time is required to modify a fascial fibrosis?
Ercole Borgini, Antonio Stecco, Julie Ann Day, Carla Stecco
This study investigated how long it takes for manual therapy to alter a palpable sensation of fascial "fibrosis" and reduce discomfort. Researchers worked with 40 people experiencing low back pain, applying the Fascial…
fasciaConnective tissueManual Therapylow back painManipulation
A
2010
Possible Applications for Fascial Anatomy and Fasciaology in Traditional Chinese Medicine
Yu Bai, Lin Yuan, Kwang-Sup Soh, Byung-Cheon Lee, Yong Huang, Chun-lei Wang, Jun Wang, Jin-peng Wu, Jing-xing Dai, Jano…
This theoretical paper proposes a new framework for understanding anatomy, called "fascial anatomy," and a new field of study, "fasciaology." The authors suggest that the body's fascial network may be the anatomical bas…
fasciameridiansacupointsprimo-vesseltraditional Chinese medicine
A
2010
Spontaneous and visible light-induced ultraweak photon emission from rat eyes
Chao Wanga, István Bókkonb, Jiapei Daia, István Antalc
In this in vitro study on rats, researchers found that isolated parts of the eye—the whole eye, lens, vitreous humor, and retina—emit extremely faint light, or photons. This photon emission occurred both spontaneously a…
fasciabioluminescent photonslipid peroxidationdiscrete dark noiseretinal phosphenes
A
2010
Fluorescent Nanoparticles for Observing Primo Vascular System Along Sciatic Nerve
Zhao-Feng Jia, Byung-Cheon Lee, Ki-Hoon Eom, Jin-Myung Cha, Jin-Kyu Lee, Zhen-Dong Su, Wen-Hui Yu, Pan Dong Ryu, Kwang-…
In this animal study, researchers injected fluorescent nanoparticles into rats at an acupuncture point to trace their path. The particles traveled along the sciatic nerve, revealing a previously hard-to-detect structure…
fasciaacupunctureSCIATIC NERVEprimo vascular systemprimo-vessel
A
2009
Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus
Ning Wang, Jessica D Tytell, Donald E Ingber
In this narrative review, the authors explore how mechanical forces can influence the cell nucleus from a distance. Research has often focused on how external forces are converted into chemical signals at the cell's sur…
fasciaextracellular matrixcytoskeletonmechanotransductioncell nucleus
A
2009
The Hard Life of Soft Cells
P A Janmey, J P Winer, M E Murray, Q Wen
This brief review explores how cells function as both mechanical and chemical machines. Cells constantly generate and respond to physical forces within their environment, the extracellular matrix. The stiffness of this…
fasciamechanotransductionsubstrate stiffnesscell mechanics
A
2009
From mechanotransduction to extracellular matrix gene expression in fibroblasts
Matthias Chiquet, Laurent Gelman, Roman Lutz, Silke Maier
This 2009 review article explores how connective tissue cells, or fibroblasts, sense and respond to mechanical forces from their environment. Cells attach to the surrounding extracellular matrix via adhesion contacts, w…
fasciaextracellular matrixfibroblastcytoskeletonmechanotransduction