Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+2007
Breathing exercises with vagal biofeedback may benefit patients with functional dyspepsia
INA E HJELLAND, SVEN SVEBAK, ARNOLD BERSTAD, GEIR FLATAB, TRYGVE HAUSKENFunctional dyspepsia (FD) is often associated with low vagus nerve tone. This study investigated whether breathing exercises with biofeedback could help. Forty patients with FD were divided into two groups; one group pr…
Biofeedbackbreathing exercisesfunctional dyspepsiavagal tone - A+2006
Dynamic Shear Stimulation of Bovine Cartilage Biosynthesis of Proteoglycan 4
Gayle E Nugent, Nicole M Aneloski, Tannin A Schmidt, Barbara L Schumacher, Michael S Voegtline, Robert L SahThis laboratory study on cartilage from young cows investigated how mechanical forces affect the production of a key lubricating molecule, proteoglycan 4 (PRG4). Researchers applied different types of loads to cartilage…
ProteoglycansCartilagePRG4dynamic shear stressstatic compression - A+2005
Coordinated collagen and muscle protein synthesis in human patella tendon and quadriceps muscle after exercise
Benjamin F Miller, Jens L Olesen, Mette Hansen, Simon Dossing, Regina M Crameri, Rasmus J Welling, Henning Langberg, Al…Researchers investigated how strenuous exercise affects protein synthesis in both muscle and tendon. In this study, healthy young men performed one-legged kicking exercises, and biopsies were taken over the next 72 hour…
Muscletendonexercisecollegen syntes - A+2005
Human Bone Collagen Synthesis Is a Rapid, Nutritionally Modulated Process
John A Babraj, Kenneth Smith, Daniel J R Cuthbertson, Peter Rickhuss, James S Dorling, Michael J RennieResearchers developed a new method to directly measure bone collagen synthesis in young, healthy men. Contrary to previous assumptions, the results showed that bone collagen formation is a surprisingly rapid process, ev…
metabolismnutritionmatrix proteinstable-isotope tracerproline - A+2005
Nutraceutical Therapies for Degenerative Joint Diseases: A Critical Review
ROBERT GOGGS, ANNE VAUGHAN-THOMAS, PETER D CLEGG, STUART D CARTER, JOHN F INNES, ALI MOBASHERI, MEHDI SHAKIBAEI, WOLFGA…This 2005 critical review examines the role of nutrition in managing degenerative joint diseases like osteoarthritis. The authors suggest that while nutritional factors are crucial for cartilage health, dietary programs…
articular cartilagenutritionosteoarthritisnutraceuticalVitamin C - A+2003
Effects of insulin lispro and chronic vitamin C therapy on postprandial lipaemia, oxidative stress and endothelial function in patients with type 2 diabetes mellitus
M Evans, R A Anderson, J C Smith, N Khan, J M Graham, A W Thomas, K Morris, D Deely, M P Frenneaux, J S Davies, A ReesPeople with type 2 diabetes often experience impaired blood vessel function and high levels of fat in their blood after eating, which are risk factors for cardiovascular disease. This study investigated whether insulin…
Oxidative stressendotheliumdiabetesinsulinpost-prandial lipaemia. - A+2003
Stress shielding of patellar tendon: effect on small-diameter collagen fibrils in a rabbit model
Tokifumi Majima, Kazunori Yasuda, Takamasa Tsuchida, Kunio Tanaka, Kiyoshi Miyakawa, Akio Minami, Kozaburo HayashiIn this animal study, researchers investigated the effects of mechanical unloading, or "stress shielding," on the patellar tendon in rabbits. The scientists completely released the tendon from its normal stress for thre…
Stress shielding · Patellar tendon · Collagen fibril diameter · Ultrastructure - A+2000
Role of collagen hydrolysate in bone and joint disease
R W MoskowitzThis narrative review examines the role of collagen hydrolysate in the management of osteoarthritis and osteoporosis. Research suggests that a daily intake of 10 grams of pharmaceutical-grade collagen hydrolysate may he…
supplementationOsteoporosishydrolysate collagenosteartrithis - A+1997
Mechanical Loading and TGF-b Regulate Proteoglycan Synthesis in Tendon
James R Robbins, Stephen P Evanko, Kathryn G VogelTendons can develop cartilage-like properties in areas subjected to compressive loading. In this study on fetal bovine tendon tissue, researchers investigated how mechanical compression affects the cells. They found tha…
load forcetissue transition