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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 37–48 of 81 studies · page 4/7A+
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A+2017

Hyaluronan as a therapeutic target in human diseases

Jiurong Liang, Dianhua Jiang, Paul W Noble

This narrative review explores the role of hyaluronan, a major component of the extracellular matrix involved in tissue injury and repair. Its function varies significantly with its size; fragmented hyaluronan can promo…

hyaluronan
A+2016

Oxidative stress and oocyte quality: ethiopathogenic mechanisms of minimal/mild endometriosis-related infertility

Michele Gomes Da Broi, Paula Andrea Navarro

In this review article, the authors explore the connection between mild endometriosis and infertility. Although the link is known, the exact mechanisms are not fully understood. The researchers suggest that poor oocyte…

Early endometriosis . Infertility . Oocyte quality . Oxidative stress . Follicular microenvironment
A+2016

The relationship between pelvic alignment and dysmenorrhea

Moon-Jeong Kim, Il-Hun Baek, Bong-Oh Goo

This study investigated the relationship between pelvic alignment and dysmenorrhea (menstrual pain). Researchers compared 102 women, divided into a group with menstrual pain and a group without, using 4D imaging to meas…

AlignmentDysmenorrheaPelvic torsion
A+2016

Health E!ects of Alkaline Diet and Water, Reduction of Digestive-tract Bacterial Load, and Earthing

Haider Abdul-Lateef Mousa

This narrative review discusses how an alkaline diet, alkaline water, reduced digestive-tract bacterial load, and “earthing” might counter chronic low-grade acidosis. The author synthesizes literature suggesting these a…

chronic inflammationearthinghypertension
A+2016

Piezo2 is the principal mechanotransduction channel for proprioception

Seung-Hyun Woo, Viktor Lukacs, Joriene C de Nooij, Dasha Zaytseva, Connor R Criddle, Allain Francisco, Thomas M Jessell…

Proprioception is the sense of where our body parts are in space. In this animal study, researchers investigated the molecular sensor responsible for this ability in mice. They found that an ion channel called Piezo2 wa…

proprioceptionmuscle spindlespiezo
A+2016

Comparison of the Hyaluronic Acid Vaginal Cream and Conjugated Estrogen Used in Treatment of Vaginal Atrophy of Menopause Women: A Randomized Controlled Clinical Trial

Azam Jokar, Tayebe Davari, Nasrin Asadi, Fateme Ahmadi, Sedighe Foruhari

This randomized controlled clinical trial compared the effectiveness of hyaluronic acid vaginal cream with conjugated estrogen cream for treating vaginal atrophy in menopausal women. Over an eight-week period, researche…

Atrophic vaginitis; Estrogen; Hyaluronic acid; Menopause
A+2016

Acute effects of muscle stretching on physical performance, range of motion, and injury incidence in healthy active individuals: a systematic review

David G Behm, Anthony J Blazevich, Anthony D Kay, Malachy McHugh

This systematic review examines how different types of stretching (static, dynamic, and PNF) affect performance, range of motion (ROM), and injury risk in healthy individuals. The findings suggest that static stretching…

ballistic stretch; dynamic stretch; facilitation neuromusculaire proprioceptive; flexibility; flexibilité; proprioceptive neuromuscular facilitation; static stretch; warm-up
A+2015

An overview of the beneficial effects of hydrolysed collagen intake on joint and bone health and on skin ageing

Teresa Figueres Juher, Esther Basés Pérez

This narrative review summarizes research on hydrolysed collagen (HC) and its impact on joint, bone, and skin health. Evidence suggests that these small collagen peptides are highly bioavailable and accumulate in connec…

supplementationOsteoporosishydrolysate collagen
A+2015

A unifying neuro-fasciagenic model of somatic dysfunction - Underlying mechanisms and treatment - Part II

Paolo Tozzi

This review paper proposes a new, unifying "neuro-fasciagenic" model for understanding somatic dysfunction. The author argues for a shift in perspective, moving from a purely neurological explanation to one where fascia…

fasciaManual Therapysomatic dysfunction
A+2015

Changes in electrical pain threshold of fascia and muscle after initial and secondary bouts of elbow flexor eccentric exercise

Wing Yin Lau, Anthony J. Blazevich, Michael J. Newton, Sam Shi Xuan Wu, Kazunori Nosaka

This study investigated how pain sensitivity changes in fascia and muscle after strenuous eccentric exercise. Ten young men performed two bouts of maximal eccentric elbow curls, four weeks apart. After the first session…

pressure pain thresholdmuscle damageRepeated bout effect
A+2015

Osmotic pressure induced tensile forces in tendon collagen

Admir Masic, Luca Bertinetti, Roman Schuetz, Shu-Wei Chang, Till Hartmut Metzger, Markus J Buehler, Peter Fratzl

Researchers investigated the role of water in tendon collagen using a combination of experiments and computer modeling. They found that water is a crucial part of the collagen molecule's structure. When water is removed…

collagenOsmotic pressurewater
A+2015

Chondroprotection and the Prevention of Osteoarthritis Progression of the Knee

Brian Gallagher, Fotios P Tjoumakaris, Marc I Harwood, Robert P Good, Michael G Ciccotti, Kevin B Freedman

In this systematic review, researchers evaluated whether certain medications and supplements could protect joint cartilage and slow the progression of knee osteoarthritis. By analyzing randomized controlled trials, they…

knee; articular cartilage; chondroprotection; nutraceutical