Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+2018
Negative Air Ions and Their Effects on Human Health and Air Quality Improvement
Shu-Ye Jiang, Ali Ma, Srinivasan RamachandranThis review paper examines the research on negative air ions (NAIs) and their effects on human health and air quality. Used for over a century in air cleaning, NAIs are associated with improved psychological health and…
negative air ions; superoxide; particulate matter; pulsed electric field - A+2018
Anatomy of the Superficial Fascia System of the Breast: A Comprehensive Theory of Breast Fascial Anatomy
Robert D Rehnke, Rachel M Groening, Eric R Van Buskirk, John M ClarkeThis study investigated the three-dimensional fascial structure of the breast through 12 cadaver dissections and clinical observations during surgery. The researchers identified a closed system of fascia and fat that su…
superficial fasciabreastreconstructive breast surgerycosmetic breast surgery - A+2018
Endogenous systems involved in exercise-induced analgesia
R DA SILVA SANTOS, G GALDINOThis narrative review describes the phenomenon of exercise-induced analgesia, which is the pain-relieving effect of physical activity. Studied since the 1970s, this effect is seen in both endurance and resistance exerci…
EndocannabinoidspainexerciseNitric oxideanalgesia - A+2018
Bone turnover markers after the menopause: T-score approach
Fatma Gossiel, Hibatallah Altaher, David M Reid, Christian Roux, Dieter Felsenberg, Claus-C Glüer, Richard EastellThis study investigated how bone turnover changes in women before and after menopause by measuring specific markers for bone formation (PINP) and bone resorption (CTX). The researchers found that bone turnover increases…
Bone mineral density; Bone turnover markers; Menopause; Osteoporosis - A+2017
The nature and biology of basement membranes
Ambra Pozzi, Peter D Yurchenco, Renato V IozzoThis review article discusses the nature and biology of basement membranes. These are thin, flexible sheets of tissue that line and separate different structures in the body. Once thought to be just passive scaffolding,…
Collagen; laminin; heparan sulfate proteoglycan; discoidin domain receptor; integrin - A+2017
The Effect of Menstrual Cycle and Contraceptives on ACL Injuries and Laxity
Simone D Herzberg, Makalapua L Motu’apuaka, William Lambert, Rongwei Fu, Jacqueline Brady, Jeanne-Marie GuiseThis systematic review and meta-analysis investigated the relationship between the menstrual cycle, hormonal contraceptives, and the risk of anterior cruciate ligament (ACL) injuries. The researchers found that knee lig…
anterior cruciate ligament; knee injury; hormonal contraceptives; female; human; menstrual cycle; systematic review; meta-analysis; sports medicine - A+2017
Effects of the menstrual cycle on lower-limb biomechanics, neuromuscular control, and anterior cruciate ligament injury risk: a systematic review
Vivek Balachandar, Jan-Luigi Marciniak, Owen Wall, Chandrika BalachandarThis systematic review evaluated how the menstrual cycle affects lower-limb biomechanics, neuromuscular control, and anterior cruciate ligament (ACL) injury risk in women. The authors found strong evidence that the risk…
Biomechanicsligamentneuromuscularcruciatemenstrual. - A+2017
Hyaluronan as a therapeutic target in human diseases
Jiurong Liang, Dianhua Jiang, Paul W NobleThis narrative review explores the role of hyaluronan, a major component of the extracellular matrix involved in tissue injury and repair. Its function varies significantly with its size; fragmented hyaluronan can promo…
hyaluronan - A+2017
Effects of vitamin C supplementation on glycaemic control: a systematic review and meta-analysis of randomised controlled trials
A W Ashor, A D Werner, J Lara, N D Willis, J C Mathers, M SiervoThis systematic review and meta-analysis compiled data from 22 randomized controlled trials to assess the effect of vitamin C supplementation on glycemic control. Overall, the researchers found no significant effect on…
Vitamin Cinsulin resistensglycaemic control - A+2017
Theoretical study of aerobic vitamin C loss kinetics during commercial heat preservation and storage
Micha PelegThis theoretical study presents a mathematical model to describe how vitamin C is lost in food during commercial heat processing and storage. The model accounts for the degradation of two forms of the vitamin, ascorbic…
Ascorbic acid; Degradation reactions; Dehydroascorbic acid; Kinetics; Storage; Thermal processing. - A+2017
Oxidative Stress and Endometriosis: A Systematic Review of the Literature
Gennaro Scutiero, Piergiorgio Iannone, Giulia Bernardi, Gloria Bonaccorsi, Savino Spadaro, Carlo Alberto Volta, Pantale…This systematic review explores the connection between oxidative stress and endometriosis, a condition where uterine-like tissue grows outside the uterus, causing pain and infertility. Oxidative stress is an imbalance b…
Oxidative stressendometriosisROS - A+2017
Quantitative tissue parameters of Achilles tendon and plantar fascia in healthy subjects using a handheld myotonometer
Sarah Orner, Wolfgang Kratzer, Julian Schmidberger, Beate GrünerThis study examined the mechanical properties of the Achilles tendon and plantar fascia in over 150 healthy adults using a handheld device called a MyotonPRO. The goal was to establish baseline normal values for tissue…
fasciaachilles tendonplantar fasciaMyotonePRO