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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 97–108 of 213 studies · page 9/18A++
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A++2018

Biotensegrity-Anatomy for the 21st Century Informing Yoga and Physiotherapy Concerning New Findings in Fascia Research

John Sharkey

This short article discusses how a new view of anatomy, called biotensegrity, is changing our understanding of the human body. This perspective focuses on fascia as a continuous, interconnected network that creates a un…

biotensegrityyogahuman anatomy
A++2018

Female hormones: do they influence muscle and tendon protein metabolism?

Mette Hansen

This narrative review examines how female sex hormones, particularly estrogen, influence the metabolism of proteins in muscles and tendons. After menopause, declining hormone levels are associated with accelerated muscl…

ACL anterior cruciate ligament; ER oestrogen receptors; ERT oestrogen replacement therapy; HRT hormone replacement therapy; IGF-I insulin-like growth factor-I; OC oral contraceptive; Collagen; Hormone replacement therapy; Muscle strength; Oestrogen; Sarcopenia.
A++2018

Vitamin C – A new player in regulation of the cancer epigenome

Linn Gillberg, Andreas D Ørskov, Minmin Liu, Laurine B S Harsløf, Peter A Jones, Kirsten Grønbæk

This narrative review explores the emerging role of vitamin C in cancer treatment, particularly in relation to epigenetics. The authors note that vitamin C is crucial for enzymes that help regulate gene expression, and…

Ascorbic acid; Cancer treatment; Epigenetics; Hematological malignancies; Vitamin C
A++2017

Touch, Tension, and Transduction - The Function and Regulation of Piezo Ion Channels

Jason Wu, Amanda H Lewis, Jörg Grandl

This narrative review explores Piezo1 and Piezo2, specialized proteins that act as the body's primary mechanical sensors. These ion channels convert physical forces like touch, tension, and fluid flow into electrical si…

Mechanotransductionpiezo
A++2017

Measuring ultra-weak photon emission as a non-invasive diagnostic tool for detecting early-stage type 2 diabetes: A step toward personalized medicine

Mengmeng Sun, Eduard Van Wijk, Slavik Koval, Roeland Van Wijk, Min He, Mei Wang, Thomas Hankemeier, Jan van der Greef

This study investigated whether ultra-weak photon emission (UPE)—a very faint light emitted by the body—could help identify different subtypes of pre-diabetes. Researchers had practitioners of Traditional Chinese Medici…

biophotonsTraditional Chinese medicin-based diagnosticsPersonalized medicine
A++2017

Massage therapy research review

Tiffany Field

This review summarizes research showing beneficial effects of massage therapy for a wide range of conditions, including prenatal depression, pain syndromes, autoimmune conditions, and issues related to aging. The author…

Massage therapy research review
A++2017

Minimizing Injury and Maximizing Return to Play: Lessons from Engineered Ligaments

Keith Baar

Musculoskeletal injuries are a primary reason for time away from sports, partly because our understanding of how training affects tendons and ligaments is limited. This study used engineered ligaments grown in a lab fro…

trainingminimizing injuryreturn to play
A++2017

Vitamin C–enriched gelatin supplementation before intermittent activity augments collagen synthesis

Gregory Shaw, Ann Lee-Barthel, Megan L R Ross, Bing Wang, Keith Baar

In a small study involving eight healthy men, researchers investigated the effect of vitamin C-enriched gelatin supplementation before exercise. Participants who consumed 15 grams of gelatin one hour before a short, int…

Bonetendonexercise
A++2017

NAD and the aging process: Role in life, death and everything in between

Claudia C S Chini, Mariana G Tarragó, Eduardo N Chini

This narrative review explores the vital role of the molecule NAD in cellular health and the aging process. Beyond its traditional role in metabolism, NAD is essential for cell signaling and regulating the epigenetic st…

Aging; CD38; Mitochondrial function; NAD(+); PARP; SIRTUINS
A++2017

EFFECT OF MATRIX RHYTHM THERAPY (MRT) COMBINED WITH PHYSIOTHERAPY INTERVENTION IN FROZEN SHOULDER – A CASE REPORT

Vijay Bhartiya, Shrikant Darade, Sandip Bhagwat, Manjumala Roy

This case report describes the treatment of a 52-year-old man with a painful and stiff right shoulder, diagnosed as frozen shoulder. His condition also involved tendinosis, bursitis, and osteoarthritic changes. The pati…

exercisesfrozen shoulderMRT
A++2017

Interaction between the gut microbiome and mucosal immune system

Na Shi, Na Li, Xinwang Duan, Haitao Niu

In this narrative review, the authors outline the two-way relationship between the gut microbiome and the mucosal immune system. A balanced microbiome is essential for the proper maturation and function of the immune sy…

inflammationMicrobiomeImmunity
A++2017

Telocytes: Connective tissue repair and communication cells

Leon Chaitow

This commentary highlights a newly identified type of connective tissue cell called a telocyte. We already know that other cells, like fibroblasts, respond to mechanical forces from manual therapy, influencing tissue re…

mechanotransductiontelocytesinterstitial cells