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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 73–84 of 213 studies · page 7/18A++
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A++2019

Ketogenic Diet and Microbiota: Friends or Enemies

Antonio Paoli, Laura Mancin, Antonino Bianco, Ewan Thomas, João Felipe Mota, Fabio Piccini

This narrative review explores the relationship between the very low-carbohydrate ketogenic diet (VLCKD) and the gut microbiota. The community of microbes in our gut is a dynamic entity known to play a fundamental role…

gut microbiota; gut microbiome; intestinal microbiome; ketogenic diet; ketogenic diet and fat
A++2019

Vitamin C Inhibits Triple-Negative Breast Cancer Metastasis by Affecting the Expression of YAP1 and Synaptopodin 2

Liping Gan, Vladimir Camarena, Sushmita Mustafi, Gaofeng Wang

In this study using cell cultures and animal models, researchers investigated how vitamin C might inhibit the spread of triple-negative breast cancer (TNBC). They found that vitamin C, at concentrations achievable throu…

F-actin; HIF-1α; YAP1; hippo pathway; lamellipodia; metastasis; synaptopodin 2; triple-negative breast cancer; vitamin C.
A++2019

The Stomach’s Communication with Its Related Acupoints, and the “Intelligent Tissue” Hypothesis

Fletcher Kovich

This study explores the "intelligent tissue" hypothesis, which suggests that an organ's functional state is reflected in real-time at specific acupuncture points. By monitoring electrical impedance at six stomach-relate…

acupunctureimpedanceduodenal
A++2019

A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study

Liane Bolke, Gerrit Schlippe, Joachim Gerß, Werner Voss

This randomized, placebo-controlled study investigated the effects of a drinkable nutraceutical containing 2.5g of collagen peptides, vitamins, and minerals on skin health in women aged 35 and older. Over twelve weeks,…

aging; beauty; bioavailability; collagen peptides; corneometry; cutometry; high coverage [HC] collagen complex; wrinkles
A++2019

Fascial organisation of motor synergies: a hypothesis

Alessandro Garofolini, Daris Svanera

This hypothesis paper explores how fascia helps organize movement through what are known as motor synergies. It suggests that instead of the brain controlling every muscle individually, the fascial system acts as a phys…

Motor control; degrees of freedom; movement coordination; muscle spindle; myofascial continuity.
A++2019

Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory

Ramesh C Gupta, Rajiv Lall, Ajay Srivastava, Anita Sinha

This narrative review explores hyaluronic acid (HA), a naturally occurring substance found in connective tissues and synovial fluid. HA is essential for joint lubrication and viscoelasticity, but its concentration and m…

hyaluronanwound healingHyaluronic acid
A++2019

Local Vibration Stimuli Induce Mechanical Stress-Induced Factors and Facilitate Recovery From Immobilization-Induced Oxidative Myofiber Atrophy in Rats

Fusako Usuki, Masatake Fujimura, Atsushi Nakamura, Jiro Nakano, Minoru Okita, Itsuro Higuchi

This study on rats investigated whether local vibration could help muscles recover after being immobilized. Researchers put a cast on one hindlimb of the rats for a week to induce muscle atrophy. After removing the cast…

YAP1; local vibration; mechano-growth factor; mechanotransduction; oxidative myofiber atrophy; satellite cell; therapeutics.
A++2019

Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients

Stephan F E Praet, Craig R Purdam, Marijke Welvaert, Nicole Vlahovich, Gregg Lovell, Louise M Burke, Jamie E Gaida, Sil…

This pilot study investigated whether supplementing with specific collagen peptides could improve symptoms for patients with chronic Achilles tendinopathy. Participants combined a calf-strengthening program with either…

achilles tendon; microvessels; contrast-enhanced ultrasound; hydrolysed collagen supplementation
A++2019

Characterization of bony changes localized to the cervical articular processes in a mixed population of horses

Kevin K Haussler, Roy R Pool, Hilary M Clayton

This observational cross-sectional study characterized bony changes in the cervical articular processes of 55 horses without primary complaints of neck pain. The researchers found that 72% of the examined joints exhibit…

cervical processes
A++2019

Rehabilitation and nutrition protocols for optimising return to play from traditional ACL reconstruction in elite rugby union players: A case study

Gregory Shaw, Ben Serpell, Keith Baar

This case report followed two professional rugby players undergoing rehabilitation after an anterior cruciate ligament (ACL) reconstruction. In addition to a standard rehabilitation program, they received specific suppl…

collagenRehabilitationnutrition
A++2019

High Cortisol and the Risk of Dementia and Alzheimer's Disease: A Review of the Literature

Sami Ouanes, Julius Popp

This literature review examines the relationship between the stress hormone cortisol and the risk of dementia and Alzheimer’s disease. The research suggests that chronically elevated cortisol levels may have deleterious…

cognition; cortisol; dementia; executive functions; memory
A++2019

8 natural supplements to help fight inflammation

Zawn Villines

Inflammation is a natural response to injury or infection, but when it becomes chronic, it can lead to long-term pain and tissue damage. This article reviews several natural supplements that may help the body manage chr…

inflammationomega-3curcumin