Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2019
Acute Effects of Static Stretching on Muscle Strength and Power: An Attempt to Clarify Previous Caveats
Helmi Chaabene, David G Behm, Yassine Negra, Urs GranacherThis narrative review examines how static stretching affects subsequent strength and power. While static stretching was once thought to hinder performance, recent evidence suggests the duration of the stretch is the cri…
physiologyrange of motioninjurypassive stretchingphysical fitness - A++2019
Inter and Intra operator reliability of motor and palpation evaluation in fascial manipulation in individuals coxarthrosis
Andrea Cotti, Massimiliano Del Corso, Roberto Diana, Luigi Cornale, Alessandra Sudanese, Antonio Stecco, Mirco BranchiniThis study investigated the reliability of assessment methods used in Fascial Manipulation® (FM®) for individuals with hip osteoarthritis (coxarthrosis). Researchers tested whether different therapists, and the same the…
Fascial manipulation; Inter reliability; intra reliability; movement evaluation; motor evaluation; palpation evaluation; coxarthrosis; pain - A++2019
Effects of Different Vitamin C–Enriched Collagen Derivatives on Collagen Synthesis
Dana M Lis, Keith BaarThis study investigated how three different forms of vitamin C-enriched collagen supplements affected markers of collagen synthesis in ten active men. Participants consumed either gelatin, hydrolyzed collagen, a gummy v…
MusculoskeletalexercisegelatinN-terminal peptide of procollageninjury - A++2019
Rehabilitation and nutrition protocols for optimising return to play from traditional ACL reconstruction in elite rugby union players: A case study
Gregory Shaw, Ben Serpell, Keith BaarThis case report followed two professional rugby players undergoing rehabilitation after an anterior cruciate ligament (ACL) reconstruction. In addition to a standard rehabilitation program, they received specific suppl…
collagenRehabilitationnutritionACL - A++2019
Role of the immune system in vascular function and blood pressure control induced by faecal microbiota transplantation in rats
Marta Toral, Iñaki Robles Vera, Néstor de la Visitación, Miguel Romero, Manuel Sánchez, Manuel Gómez Guzmán, Alba Rodri…This animal study investigated the link between gut bacteria, the immune system, and blood pressure in rats. Researchers transplanted gut microbiota between spontaneously hypertensive rats and rats with normal blood pre…
hypertensionendothelial dysfunctiongut dysbiosisimmune cells - A++2019
Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure
Alpha A Fowler, Jonathon D Truwit, R Duncan Hite, Peter E Morris, Christine DeWilde, Anna Priday, Bernard Fisher, Leroy…This randomized controlled trial investigated whether intravenous vitamin C could help patients with sepsis and severe acute respiratory failure. Researchers gave 167 patients either a high-dose vitamin C infusion or a…
sepsisintravenous vitamin C - A++2019
Vitamin C Can Shorten the Length of Stay in the ICU: A Meta-Analysis
Harri Hemilä, Elizabeth ChalkerThis meta-analysis reviewed data from 18 controlled trials involving over 2000 patients to assess if vitamin C affects the length of stay in the intensive care unit (ICU). The results suggest that vitamin C supplementat…
antioxidants; burns; artificial respiration; cardiac surgical procedures; cardiovascular system; critical care; dietary supplements; oxidative stress; sepsis; systematic review - A++2019
Fascial organisation of motor synergies: a hypothesis
Alessandro Garofolini, Daris SvaneraThis hypothesis paper explores how fascia helps organize movement through what are known as motor synergies. It suggests that instead of the brain controlling every muscle individually, the fascial system acts as a phys…
Motor control; degrees of freedom; movement coordination; muscle spindle; myofascial continuity. - A++2019
Observation using thermography of post-operative reaction after fascial manipulation®
Joanna Fidut-Wrońska, Kamil Chołuj, Justyna Chmiel, Katarzyna Pikto-Pitkiewicz, Piotr MajcherThis study investigated whether Fascial Manipulation® causes a local increase in skin temperature, which is theorized to be part of its mechanism. Researchers used a thermal-imaging camera to measure skin temperature in…
inflammationFascial manipulationthermography - A++2019
Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory
Ramesh C Gupta, Rajiv Lall, Ajay Srivastava, Anita SinhaThis narrative review explores hyaluronic acid (HA), a naturally occurring substance found in connective tissues and synovial fluid. HA is essential for joint lubrication and viscoelasticity, but its concentration and m…
hyaluronanwound healingHyaluronic acidosteoarthritiscancer therapy - A++2019
Vitamin C Inhibits Triple-Negative Breast Cancer Metastasis by Affecting the Expression of YAP1 and Synaptopodin 2
Liping Gan, Vladimir Camarena, Sushmita Mustafi, Gaofeng WangIn this study using cell cultures and animal models, researchers investigated how vitamin C might inhibit the spread of triple-negative breast cancer (TNBC). They found that vitamin C, at concentrations achievable throu…
F-actin; HIF-1α; YAP1; hippo pathway; lamellipodia; metastasis; synaptopodin 2; triple-negative breast cancer; vitamin C. - A++2019
Induced lumbosacral radicular symptom referral patterns: a descriptive study
Michael B Furman, Stephen C JohnsonThis observational study investigated actual pain patterns caused by irritating specific nerve roots in the lower back. Clinicians often use standard 'dermatome' maps to diagnose the source of radiating leg pain, but pa…
dermatomes; nerve; communications; map; cutaneous; sensory