Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2019
Characterization of bony changes localized to the cervical articular processes in a mixed population of horses
Kevin K Haussler, Roy R Pool, Hilary M ClaytonThis observational cross-sectional study characterized bony changes in the cervical articular processes of 55 horses without primary complaints of neck pain. The researchers found that 72% of the examined joints exhibit…
cervical processes - A++2019
Ketogenic Diet and Microbiota: Friends or Enemies
Antonio Paoli, Laura Mancin, Antonino Bianco, Ewan Thomas, João Felipe Mota, Fabio PicciniThis narrative review explores the relationship between the very low-carbohydrate ketogenic diet (VLCKD) and the gut microbiota. The community of microbes in our gut is a dynamic entity known to play a fundamental role…
gut microbiota; gut microbiome; intestinal microbiome; ketogenic diet; ketogenic diet and fat - A++2019
Effects of Different Vitamin C–Enriched Collagen Derivatives on Collagen Synthesis
Dana M Lis, Keith BaarThis study investigated how three different forms of vitamin C-enriched collagen supplements affected markers of collagen synthesis in ten active men. Participants consumed either gelatin, hydrolyzed collagen, a gummy v…
MusculoskeletalexercisegelatinN-terminal peptide of procollageninjury - A++2019
Local Vibration Stimuli Induce Mechanical Stress-Induced Factors and Facilitate Recovery From Immobilization-Induced Oxidative Myofiber Atrophy in Rats
Fusako Usuki, Masatake Fujimura, Atsushi Nakamura, Jiro Nakano, Minoru Okita, Itsuro HiguchiThis study on rats investigated whether local vibration could help muscles recover after being immobilized. Researchers put a cast on one hindlimb of the rats for a week to induce muscle atrophy. After removing the cast…
YAP1; local vibration; mechano-growth factor; mechanotransduction; oxidative myofiber atrophy; satellite cell; therapeutics. - A++2019
Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure
Alpha A Fowler, Jonathon D Truwit, R Duncan Hite, Peter E Morris, Christine DeWilde, Anna Priday, Bernard Fisher, Leroy…This randomized controlled trial investigated whether intravenous vitamin C could help patients with sepsis and severe acute respiratory failure. Researchers gave 167 patients either a high-dose vitamin C infusion or a…
sepsisintravenous vitamin C - A++2019
Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients
Stephan F E Praet, Craig R Purdam, Marijke Welvaert, Nicole Vlahovich, Gregg Lovell, Louise M Burke, Jamie E Gaida, Sil…This pilot study investigated whether supplementing with specific collagen peptides could improve symptoms for patients with chronic Achilles tendinopathy. Participants combined a calf-strengthening program with either…
achilles tendon; microvessels; contrast-enhanced ultrasound; hydrolysed collagen supplementation - A++2019
High Cortisol and the Risk of Dementia and Alzheimer's Disease: A Review of the Literature
Sami Ouanes, Julius PoppThis literature review examines the relationship between the stress hormone cortisol and the risk of dementia and Alzheimer’s disease. The research suggests that chronically elevated cortisol levels may have deleterious…
cognition; cortisol; dementia; executive functions; memory - A++2019
8 natural supplements to help fight inflammation
Zawn VillinesInflammation is a natural response to injury or infection, but when it becomes chronic, it can lead to long-term pain and tissue damage. This article reviews several natural supplements that may help the body manage chr…
inflammationomega-3curcumin - A++2019
A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study
Liane Bolke, Gerrit Schlippe, Joachim Gerß, Werner VossThis randomized, placebo-controlled study investigated the effects of a drinkable nutraceutical containing 2.5g of collagen peptides, vitamins, and minerals on skin health in women aged 35 and older. Over twelve weeks,…
aging; beauty; bioavailability; collagen peptides; corneometry; cutometry; high coverage [HC] collagen complex; wrinkles - A++2019
Effects of season long participation on ACL volume in female intercollegiate soccer athletes
Karen M Myrick, Andreas Voss, Richard S Feinn, Thomas Martin, Bernadette M Mele, Juan C GarbalosaThis study investigated how a competitive season affects the anterior cruciate ligament (ACL) in female collegiate soccer players. Researchers used MRI scans to measure ACL volume in 17 athletes before and after their s…
collagenAnterior cruciate ligamentintense physical trainingvolumetric changes in ligamentpre- to post season changes in ligament - A++2019
Fascial Entrapment Neuropathy
ANTONIO STECCO, CARMELO PIRRI, CARLA STECCOThis narrative review explores how fascia can contribute to nerve entrapment syndromes, which cause pain, sensory abnormalities, and weakness. The authors describe how nerves are surrounded by a microenvironment of conn…
nerve; nerve entrapment; fascia; Parsonage-Turner - A++2019
A History of Fascia
Sue Adstrum, H NicholsonThis historiographic review surveys how the anatomical term "fascia" has been portrayed throughout history. The authors found that its meaning has varied considerably during the 400 years the term has been used in Engli…
anatomical terminology; fascia; fascial system; integrative anatomy; medical history