Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2020
Sensitivity of the Fasciae to the Endocannabinoid System: Production of Hyaluronan-Rich Vesicles and Potential Peripheral Effects of Cannabinoids in Fascial Tissue
Caterina Fede , Carmelo Pirri , Lucia Petrelli, Diego Guidolin , Chenglei Fan, Raffaele De Caro, Carla SteccoThis laboratory study investigated how fascial cells respond to cannabinoids. Researchers isolated fibroblast cells from human fascia lata and treated them with a substance that activates cannabinoid receptor 2. The tre…
fascia; hyaluronan; vesicles; endocannabinoid; agonist; antagonist; inflammation; fibrosis; pain; peripheral effect - A++2020
The Efficacy of Stretching Exercises on Arterial Stiffness in Middle-Aged and Older Adults: A Meta-Analysis of Randomized and Non-Randomized Controlled Trials
Michitaka Kato, Fumi Nihei Green, Kazuki Hotta, Toshiya Tsukamoto, Yasunari Kurita, Akira Kubo, Hisato TakagiThis meta-analysis reviewed eight studies involving 213 middle-aged and older adults to see how stretching affects arterial stiffness. The combined results suggest that regular stretching can significantly reduce arteri…
stretching exercises; arterial stiffness; endothelial function; middle-aged; older adult - A++2020
Simulation and Modeling of Telocytes Behavior in Signaling and Intercellular Communication Processes
Dragos Cretoiu, Simona Roatesi, Ion Bica, Cezar Plesca, Amado Stefan, Oana Bajenaru, Carmen Elena Condrat, Sanda Maria…Telocytes are a unique type of interstitial cell with long extensions that form networks, thought to be involved in local tissue equilibrium and regeneration. In this study, researchers used computer simulation and math…
content-based image retrieval; image indexation; modeling of living cell behavior; telocyte network tracking and indexing; telocytes; viscoelastic constitutive laws - A++2020
Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk
Lijun Wang, Xiuling You, Sutada Lotinun, Lingli Zhang, Nan Wu, Weiguo ZouThis study using mouse models investigates how the protein PIEZO1 acts as a mechanical sensor in the skeleton to regulate bone mass. Researchers found that a deficiency of PIEZO1 in bone-forming cells (osteoblasts) lead…
mechanotransductionpiezobone homeostasis - A++2020
Embryology of the Fascial System
Leonardo VieiraThis review article explores how the fascial system develops in the human embryo, highlighting its role as a continuous network that integrates all body systems. The author describes how different types of fascia—includ…
embryology; fascia; fascial system; human development; neuro-fasciagenic