Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2020
Nutrition, immunity and COVID-19
Philip C CalderThis review discusses the crucial role of nutrition in supporting the immune system's ability to fight infections. A well-functioning immune response requires a steady supply of energy and specific nutrients derived fro…
immune systemVitamins.nutrientsgut microbiome - A++2020
Extracellular Vesicles Released From Articular Chondrocytes Play a Major Role in Cell-Cell Communication
Xiaoming Liu, Claire Shortt, Fenglin Zhang, Mariah Q Bater, Mary K Cowman, Thorsten KirschThis narrative review examines the role of extracellular vesicles (EVs) as crucial mediators in cell-to-cell communication. EVs are small, lipid-enclosed particles that transport proteins, lipids, and genetic material t…
articular chondrocytes; catabolic events; chondrogenesis; extracellular vesicles - A++2020
The Structure and Role of Intramuscular Connective Tissue in Muscle Function
Peter P PurslowThis narrative review analyzes the microscopic structure of intramuscular connective tissue—endomysium, perimysium, and epimysium—and its role in muscle function. Rather than acting simply as a container, this connectiv…
extracellular matrixMusclecollagenmechanotransductionperimysium - A++2020
Ultrasound imaging of a scar on the knee: Sonopalpation for fascia and subcutaneous tissues
Carmelo Pirri, Antonio Stecco, Caterina Fede, Raffaele De Caro, Carla Stecco, Levent ÖzçakarPersistent pain from surgical or trauma-related scars is a common and sometimes debilitating problem. In this article, the authors describe the use of ultrasound imaging to provide an objective diagnosis for debilitatin…
fasciapainscarultrasonographyknee - A++2020
Applicability of Low-intensity Vibrations as a Regulatory Factor on Stem and Progenitor Cell Populations
Oznur Baskan, Ozge Karadas, Gulistan Mese, Engin OzciviciThis narrative review explores how mechanical forces, specifically low-intensity vibrations, can influence stem cells. While high-impact activities like running are known to build tissue, they are not suitable for every…
Stem cell; biomechanics; mechanobiology; progenitor cell populations; tissue engineering; vibrations - A++2020
Is the extent of obstetric anal sphincter injury correlated with the severity of fecal incontinence in the long term?
L Luciano, M. Bouvier, K Baumstarck, V VittonThis retrospective study investigated the relationship between the extent of obstetric anal sphincter injury and the severity of long-term fecal incontinence (FI). Researchers analyzed data from 250 women with a mean ag…
Fecal incontinence · Obstetrical anal sphincter injury · Endoanal ultrasonography · 3D high-resolution anorectal manometry · Delivery - A++2020
The potential of cannabidiol in the COVID-19 pandemic
Giuseppe Esposito, Marcella Pesce, Luisa Seguella, Walter Sanseverino, Jie Lu, Chiara Corpetti, Giovanni SarnelliThis scientific hypothesis explores the potential of cannabidiol (CBD) as a supportive treatment during the COVID-19 pandemic. The authors suggest that CBD may down-regulate the receptors the virus uses for cellular ent…
fibrosisCannabinoidsimmune systemCOVID-19anti-inflammatory - A++2020
Effect of Low-Intensity Vibration on Bone Strength, Microstructure, and Adiposity in Pre-Osteoporotic Postmenopausal Women: A Randomized Placebo-Controlled Trial
Chamith S Rajapakse, Alyssa J Johncola, Alexandra S Batzdorf, Brandon C Jones, Mona Al Mukaddam, Kelly Sexton, Justine…This randomized, placebo-controlled trial investigated if daily low-intensity vibration could improve bone health in postmenopausal women with pre-osteoporosis. For one year, one group used a vibrating platform for 10 m…
VIBRATION THERAPY; BONE; OSTEOPOROSIS; MRI - A++2020
The potential role of cannabinoids in dermatology
Tabrez Sheriff, Matthew J Lin, Danielle Dubin, Hooman KhorasaniThis literature review explores how cannabinoids, including both plant-derived and endogenous versions, may affect the skin through the endocannabinoid system. Research suggests that the skin possesses its own receptors…
Cannabinoids in dermatology; cannabidiol; cannabis; endocannabinoids. - A++2020
Mesothelial Cells Covering the Surface of Primo Vascular System Tissue
Chae Jeong Lim, Yeo Sung Yoon, Pan Dong RyuIn this study on rats, researchers investigated the cells on the outer surface of the primo vascular system (PVS), a proposed circulatory network. Using various microscopy and staining techniques, they identified these…
HBME-1; hematoxylin and eosin staining (H&E); periductium; primo node; primo vessel; scanning electron microscopy (SEM) - A++2020
Higher Circulating Cortisol in the Follicular vs. Luteal Phase of the Menstrual Cycle: A Meta-Analysis
Ajna Hamidovic, Kristina Karapetyan, Fadila Serdarevic, So Hee Choi, Tory Eisenlohr-Moul, Graziano PinnaThis meta-analysis investigated how levels of the stress hormone cortisol vary across the menstrual cycle in healthy women. By synthesizing data from multiple high-quality studies, researchers found that cortisol levels…
cortisol; follicular; hypothalamic-pituitary-adrenal (HPA) axis; hypothalamic-pituitary-gonadal (HPG) axis; luteal; menstrual cycle - A++2020
Therapeutic importance of hydrogen sulfide in age-associated neurodegenerative diseases
Rubaiya Tabassum, Na Young Jeong, Junyang JungThis narrative review explores the potential of molecular hydrogen (H2) as a preventive and therapeutic medical gas for various health conditions. H2 acts as a selective antioxidant, specifically targeting the most harm…
3-mercaptopyruvate sulfurtransferase; aging; antioxidant; cystathionine β-synthase; cystathionine γ-lyase; glutathione; hydrogen sulfide; neurodegenerative disease; oxidative stress; reactive oxygen species