Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2021
Therapeutic potential of astaxanthin and superoxide dismutase in Alzheimer's disease
Vyshnavy Balendra, Sandeep Kumar SinghThis narrative review explores how the combination of astaxanthin and the enzyme superoxide dismutase (SOD) may help protect the brain in Alzheimer's disease. Oxidative stress is a key factor in the disease's progressio…
Alzheimer's disease; astaxanthin; neurodegeneration; nutraceuticals; oxidative stress; superoxide dismutase (SOD) - A++2021
Is "Delayed Onset Muscle Soreness" a False Friend? The Potential Implication of the Fascial Connective Tissue in Post-Exercise Discomfort
Jan Wilke, Michael BehringerThis narrative review explores the theory that delayed onset muscle soreness (DOMS) may originate in the connective tissue (fascia) rather than the muscle fibers themselves. While traditional explanations like lactic ac…
DOMS; athletes; eccentric exercise; fascia; pain. - A++2021
Altering Dynamics of Autonomic Processing Therapy (ADAPT) trial: a novel, targeted treatment for reducing anxiety in joint hypermobility
Geoff Davies, Jenny L L Csecs, Heather Ball, Jess Dare, Stephen Bremner, Robin Hosking, Hugo D Critchley, Nick Grey, Je…This paper describes the protocol for a clinical trial investigating a new therapy for anxiety in people with joint hypermobility. The proposed therapy, called ADAPT, combines bio-behavioral training with cognitive appr…
InteroceptionhypermobilityAnxietyCBTRCT - A++2021
Beyond bones: The relevance of variants of connective tissue (hypermobility) to fibromyalgia, ME/CFS and controversies surrounding diagnostic classification: an observational study
Jessica A Eccles, Beth Thompson, Kristy Themelis, Marisa L Amato, Robyn Stocks, Amy Pound, Anna-Marie Jones, Zdenka Cip…This observational study investigated the link between hypermobility, fibromyalgia, and ME/CFS. Researchers found a significant overlap in symptoms between fibromyalgia and ME/CFS in the patient group. A large majority…
FibromyalgiapainfatiguehypermobilityME/CFS - A++2021
Decoding the silent walk of COVID-19: Halting its spread using old bullets
Mukesh Kumar, Jitender Madan, Rupinder Kaur Sodhi, Shashi Bala Singh, Anju KatyalThis 2021 review article explores the strategy of using existing drugs to combat the rapidly spreading COVID-19 virus. The authors describe how SARS-CoV-2 affects multiple organ systems, creating a significant therapeut…
Chloroquine; Heparin; Noscapine; Remedesivir; Severe acute respiratory syndrome (SARS-CoV2); Vitamin C. - A++2020
What is the Intelligent Tissue !eory and How Does it Relate to Acupuncture?
Fletcher KovichThis article introduces the "intelligent tissue theory," which proposes that organ information is transmitted via electromagnetic waves and interpreted by bodily tissues at specific meridians. The author suggests that t…
acupunctureChiintelligent tissueNei Jing - A++2020
Telocytes and lymphatic endothelial cells: Two immunophenotypically distinct and spatially close cell entities
Irene Rosa, Mirca Marini, Eleonora Sgambati, Lidia Ibba-Manneschi, Mirko ManettiResearchers have been working to clarify the identity of two cell types, telocytes and lymphatic endothelial cells, which can sometimes look similar in tissue samples. This study used a specific staining technique to lo…
Telocytes and lymphatic endothelial cells: Two immunophenotypically distinct and spatially close cell entities - A++2020
The potential role of cannabinoids in dermatology
Tabrez Sheriff, Matthew J Lin, Danielle Dubin, Hooman KhorasaniThis literature review explores how cannabinoids, including both plant-derived and endogenous versions, may affect the skin through the endocannabinoid system. Research suggests that the skin possesses its own receptors…
Cannabinoids in dermatology; cannabidiol; cannabis; endocannabinoids. - A++2020
Fascia and soft tissues innervation in the human hip and their possible role in post-surgical pain
Caterina Fede, Andrea Porzionato, Lucia Petrelli, Chenglei Fan, Carmelo Pirri, Carlo Biz, Raffaele De Caro, Carla SteccoResearchers investigated the nerve supply to various soft tissues in the human hip to better understand persistent pain after hip replacement surgery. Analyzing tissue samples from patients and cadavers, they measured t…
fasciapaininnervationproprioceptionSoft tissue - A++2020
Biotensegrity: What is the big deal?
Graham ScarrDetails for this entry have not yet been summarized. The title, "Biotensegrity: What is the big deal?", suggests it is an explanatory or editorial piece about the concept of biotensegrity. Biotensegrity is a model that…
biotensegrity - A++2020
Local low-intensity vibration improves healing of muscle injury in mice
Thomas F Corbiere, Timothy J KohIn this animal study, researchers investigated how local low-intensity vibration (LIV) affects muscle injury healing in mice. After lacerating the gastrocnemius (calf) muscle in mice, one group received daily vibration…
skeletal muscle injurycell culturemechanical stimulationmouse modelmuscle repair - A++2020
Simulation and Modeling of Telocytes Behavior in Signaling and Intercellular Communication Processes
Dragos Cretoiu, Simona Roatesi, Ion Bica, Cezar Plesca, Amado Stefan, Oana Bajenaru, Carmen Elena Condrat, Sanda Maria…Telocytes are a unique type of interstitial cell with long extensions that form networks, thought to be involved in local tissue equilibrium and regeneration. In this study, researchers used computer simulation and math…
content-based image retrieval; image indexation; modeling of living cell behavior; telocyte network tracking and indexing; telocytes; viscoelastic constitutive laws