Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2022
Lifestyle Factors and Their Influence on Rheumatoid Arthritis: A Narrative Review
Christoph Schäfer, Gernot KeyßerThis narrative review examines how lifestyle factors influence the development and progression of rheumatoid arthritis (RA). Research suggests that smoking, an unhealthy diet, and obesity increase the risk of developing…
Mediterranean diet; diet; lifestyle; physical activity; rheumatoid arthritis; smoking; socioeconomic status - A++2022
Risk Factors of Postpartum Depression
Iris Agrawal, Ashok M Mehendale, Ritika MalhotraThis literature review examines the risk factors for postpartum depression (PPD), a condition affecting 10–15% of new mothers globally. The research suggests that factors such as a history of psychiatric illness, lack o…
clinical features; history of depression; post-natal mother; postnatal depression; postpartum care; postpartum depression; postpartum mental health; postpartum mothers; risk factors; spousal support. - A++2022
Blood supply to the superficial fascia of the abdomen:An anatomical study
Carmelo Pirri, Lucia Petrelli, Caterina Fede, Diego Guidolin, Cesare Tiengo, Raffaele De Caro, Carla SteccoThis anatomical study investigated the blood supply to Scarpa's fascia, the superficial fascia of the abdominal wall, using tissue samples from seven volunteers. The researchers demonstrated that this fascia is a highly…
Subcutaneous tissueFlapssuperficial fasciahypodermislymphatics - A++2022
Mechanosensing by Piezo1 and its implications for physiology and various pathologies
Austin Lai, Charles D Cox, Nadia Chandra Sekar, Peter Thurgood, Anthony Jaworowski, Karlheinz Peter, Sara BaratchiThis narrative review explores Piezo1, a specialized ion channel that senses mechanical pressure and converts it into biological signals within the body. These channels are widely distributed in tissues such as blood ve…
Piezo1; mechanoreceptor; mechanosensitive ion channel; mechanotransduction; shear stress. - A++2022
Interdisciplinarity and mechanobiology
Donald E Ingber, Dino Di CarloMechanobiology is an interdisciplinary field that studies how cells sense and respond to mechanical forces in their environment. In this article, pioneers Donald Ingber and Dino Di Carlo discuss how physical forces infl…
biotensegrity - A++2022
The effect of low-intensity whole-body vibration with or without high-intensity resistance and impact training on risk factors for proximal femur fragility fracture in postmenopausal women with low bone mass: study protocol for the VIBMOR randomized controlled trial
Belinda Beck, Clinton Rubin, Amy Harding, Sanjoy Paul, Mark ForwoodThis document outlines the plan for a clinical trial investigating non-drug approaches for low bone mass in postmenopausal women. The study will compare the effects of low-intensity whole-body vibration, high-intensity…
exercisevibrationFractureHiRITOsteoporosis - A++2021
Is "Delayed Onset Muscle Soreness" a False Friend? The Potential Implication of the Fascial Connective Tissue in Post-Exercise Discomfort
Jan Wilke, Michael BehringerThis narrative review explores the theory that delayed onset muscle soreness (DOMS) may originate in the connective tissue (fascia) rather than the muscle fibers themselves. While traditional explanations like lactic ac…
DOMS; athletes; eccentric exercise; fascia; pain. - A++2021
Temporomandibular Myofascial Pain Syndrome-Aetiology and Biopsychosocial Modulation. A Narrative Review
Paulina Golanska, Klara Saczuk, Monika Domarecka, Joanna Kuć, Monika Lukomska-SzymanskaThis case report examined the effectiveness of Global Postural Reeducation (GPR) in treating a 23-year-old woman with temporomandibular disorder (TMD) and postural imbalances. By addressing muscle chains and spinal alig…
biopsychosocial profile modulation; bruxism; limbic system; stress; temporomandibular myofascial pain syndrome - A++2021
Decoding the silent walk of COVID-19: Halting its spread using old bullets
Mukesh Kumar, Jitender Madan, Rupinder Kaur Sodhi, Shashi Bala Singh, Anju KatyalThis 2021 review article explores the strategy of using existing drugs to combat the rapidly spreading COVID-19 virus. The authors describe how SARS-CoV-2 affects multiple organ systems, creating a significant therapeut…
Chloroquine; Heparin; Noscapine; Remedesivir; Severe acute respiratory syndrome (SARS-CoV2); Vitamin C. - A++2021
Therapeutic potential of astaxanthin and superoxide dismutase in Alzheimer's disease
Vyshnavy Balendra, Sandeep Kumar SinghThis narrative review explores how the combination of astaxanthin and the enzyme superoxide dismutase (SOD) may help protect the brain in Alzheimer's disease. Oxidative stress is a key factor in the disease's progressio…
Alzheimer's disease; astaxanthin; neurodegeneration; nutraceuticals; oxidative stress; superoxide dismutase (SOD) - A++2021
Beyond bones: The relevance of variants of connective tissue (hypermobility) to fibromyalgia, ME/CFS and controversies surrounding diagnostic classification: an observational study
Jessica A Eccles, Beth Thompson, Kristy Themelis, Marisa L Amato, Robyn Stocks, Amy Pound, Anna-Marie Jones, Zdenka Cip…This observational study investigated the link between hypermobility, fibromyalgia, and ME/CFS. Researchers found a significant overlap in symptoms between fibromyalgia and ME/CFS in the patient group. A large majority…
FibromyalgiapainfatiguehypermobilityME/CFS - A++2021
Physical Agent Modalities in Early Osteoarthritis: A Scoping Review
Giulia Letizia Mauro, Dalila Scaturro, Francesca Gimigliano, Marco Paoletta, Sara Liguori, Giuseppe Toro, Giovanni Iola…This scoping review investigated the role of physical agent modalities in treating early osteoarthritis (EOA). Researchers searched for studies on treatments like TENS, extracorporeal shockwave therapy (ESWT), ultrasoun…
osteoarthritis; early osteoarthritis; rehabilitation; physical therapy modalities; physical agents; electric stimulation therapy; pulsed electromagnetic field; extracorporeal shockwave therapy; vibration therapy