Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2014
Ultra-weak photon emission from biological samples: Definition, mechanisms, properties, detection and applications
Michal Cifra, Pavel PospíšilThis review article summarizes the current understanding of ultra-weak photon emission (UPE), a faint light naturally produced by living organisms. This light, a form of chemiluminescence, is generated during normal met…
biophotonsChemiluminescenceOxidative stressSinglet oxygenCharge coupled device - A++2014
The Role of Functional Foods in Cutaneous Anti-aging
Soyun ChoThis narrative review examines how functional foods and oral supplements may influence skin aging by addressing oxidative stress and inflammation. Research suggests that compounds such as carotenoids, aloe vera, red gin…
Anti-oxidant; Collagen; Functional foods; Photoaging - A++2014
Age- and diabetes-related nonenzymatic crosslinks in collagen fibrils: Candidate amino acids involved in Advanced Glycation End-products
Alfonso Gautieri, Alberto Redaelli, Markus J Buehler, Simone VesentiniAdvanced Glycation End-products (AGEs) are harmful crosslinks that form in collagen with aging and in diabetes, making tissues stiffer. However, the exact location of these crosslinks has been unclear. In this theoretic…
Advanced glycation end-products; Ageing; Atomistic simulations; Collagen; Crosslinks; Diabetes. - A++2014
Spatiotemporal Imaging of Glutamate-Induced Biophotonic Activities and Transmission in Neural Circuits
Rendong Tang, Jiapei DaiThis study on mouse brain tissue investigated biophotons, which are ultra-weak light emissions from biological systems. Researchers found that applying the neurotransmitter glutamate caused a significant and long-lastin…
fasciabiophotonsultraweak photons - A++2014
New perspective in cell communication: Potential role of ultra-weak photon emission
Ankush Prasad, Claudio Rossi, Stefania Lamponi, Pavel Pospíšil, Alberto FolettiThis 2014 narrative review explores how cells might communicate with each other. Beyond chemical signals and direct contact, the authors discuss evidence for communication via electromagnetic radiation, specifically ult…
fasciabiophotonsUltra-weak photon emissioncellular interactionbiocommunication - A++2014
Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study
E Proksch, D Segger, J Degwert, M Schunck, V Zague, S OesserThis double-blind, placebo-controlled study investigated the effects of daily collagen peptide supplementation in individuals with knee osteoarthritis. Participants received either porcine or bovine collagen, or a place…
skin agingCollagen hydrolysatecollagen peptidesskin health. - A++2013
Squeeze film lubrication for non-Newtonian fluids with application to manual medicine
Hans Chaudhry, Bruce Bukiet, Max Roman, Antonio Stecco, Thomas FindleyResearchers used a mathematical model to investigate how manual therapy affects the fluid in and around fascia. The model focused on hyaluronic acid (HA), a natural lubricant in connective tissue. The results suggest th…
fasciaHyaluronic acidmassage therapyvibrationsmanual manipulation - A++2013
Mathematical Analysis of the Flow of Hyaluronic Acid Around Fascia During Manual Therapy Motions
Max Roman, Hans Chaudhry, Bruce Bukiet, Antonio Stecco,Thomas FindleyThis study used a mathematical model to simulate how different manual therapy techniques affect the flow of hyaluronic acid (HA) within fascia. The researchers compared constant sliding, perpendicular vibration, and tan…
hyaluronanfasciaManual Therapyfluid flowvibration - A++2013
Vitamin C in Disease Prevention and Cure: An Overview
Shailja Chambial, Shailendra Dwivedi, Kamla Kant Shukla, Placheril J John, Praveen SharmaThis narrative review provides an overview of Vitamin C's many roles in the body. It is essential for developing and maintaining connective tissues, and plays a key part in bone formation, wound healing, and gum health.…
cancerdiabetesVitamin CImmunityinfertility - A++2013
Vibration Induced Osteogenic Commitment of Mesenchymal Stem Cells is Enhanced by Cytoskeletal Remodeling but not Fluid Shear
Gunes Uzer, Suphannee Pongkitwitoon, M Ete Chan, Stefan JudexThis laboratory study investigated how mechanical vibrations encourage stem cells to develop into bone cells. Researchers tested two potential mechanisms: the force of fluid moving across the cells (fluid shear) and cha…
fasciaBonedifferentiationProliferationvibrations - A++2013
Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin-C deficient mice
John Cha, M Waheed Roomi, Vadim Ivanov, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias RathThis animal study investigated how Vitamin C (ascorbate) supplementation affects cancer growth in mice that, like humans, cannot produce their own. Researchers injected melanoma or breast cancer cells into two groups of…
Tumor growthinterleukin-6apoptosismetastasisascorbate - A++2013
The application of matrix rhythm therapy as a new clinical modality in burn physiotherapy programmes
Zübeyir Sarı, Mine Gülden Polat, Bahar Özgül, Onur Aydogdu, Burcu Camcıoglu, Ahmet Hakan Acar, Saadet Ufuk YurdalanThis study investigated the use of Matrix Rhythm Therapy (MRT) as part of a physiotherapy program for patients with upper extremity burn injuries. A group of patients received a treatment protocol that included whirlpoo…
Matrix Rhythm TherapyBurnsPhysiotherapy and rehabilitation