Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2015
Estrogen inhibits lysyl oxidase and decreases mechanical function in engineered ligaments
Cassandra A Lee, Ann Lee-Barthel, Louise Marquino, Natalie Sandoval, George R Marcotte, Keith BaarThis lab study investigated why women are more likely to rupture their anterior cruciate ligament (ACL) than men, focusing on the role of estrogen. Researchers used human ACL cells to create engineered ligaments in a la…
ACL; exercise; tendon; ultimate tensile strength - A++2015
Fruit, vegetable and vitamin C intakes and plasma vitamin C: cross-sectional associations with insulin resistance and glycaemia in 9-10 year-old children
A S Donin, J E Dent, C M Nightingale, N Sattar, C G Owen, A R Rudnicka, M R Perkin, A M Stephen, S A Jebb, D G Cook, P…This cross-sectional study of over 2000 children in the UK examined the relationship between vitamin C and risk factors for type 2 diabetes. Researchers found that higher levels of vitamin C in the blood were associated…
Vitamin Cinsulin resistensglycaemiadiabetes type 2 - A++2014
Vibration therapy: clinical applications in bone
William R Thompson, Sherwin S Yen, Janet RubinThis review article explores vibration therapy as a way to mimic the positive effects of physical activity on bone and muscle, especially for frail individuals who cannot exercise. Animal and human studies suggest that…
low-intensity vibration; mesenchymal stem cells; osteocyte; osteoporosis - A++2014
Role of reactive oxygen species in ultra-weak photon emission in biological systems
Pavel Pospíšil, Ankush Prasad, Marek RácThis narrative review explores the connection between reactive oxygen species (ROS) and the faint light, or ultra-weak photon emission, that living organisms naturally produce. The authors explain that normal metabolic…
biophotonsChemiluminescenceReactive oxygen specieslipid peroxidationHydroxyl radical - A++2014
Ultraweak photon emission as a non-invasive health assessment: a systematic review
John A Ives, Eduard P A van Wijk, Namuun Bat, Cindy Crawford, Avi Walter, Wayne B Jonas, Roeland van Wijk, Jan van der…This systematic review explores the use of ultraweak photon emission (UPE) as a non-invasive tool for assessing human health. By analyzing 56 studies, researchers found that measuring light particles emitted by the body…
Ultra-weak photon emissionultra-weak bioluminescencehealt assessment - A++2014
Low-intensity vibration improves angiogenesis and wound healing in diabetic mice
Eileen M Weinheimer-Haus, Stefan Judex, William J Ennis, Timothy J KohThis animal study investigated if whole-body low-intensity vibration (LIV) could improve chronic wound healing in diabetic mice. Mice with surgical wounds received either 30 minutes of daily vibration or a sham treatmen…
wound healingvibrationsdiabetic wounds - A++2014
Ingested hyaluronan moisturizes dry skin
Chinatsu Kawada, Takushi Yoshida, Hideto Yoshida, Ryosuke Matsuoka, Wakako Sakamoto, Wataru Odanaka, Toshihide Sato, Ta…This review article summarizes research on how oral hyaluronan (HA) supplements may influence skin hydration levels. Studies suggest that a daily intake of 120–240 mg of hyaluronic acid can contribute to increased moist…
hyaluronanhaHyaluronic acidSkinsupplementation - A++2014
Towards whole-body ultra-weak photon counting and imaging with a focus on human beings: A review
Roeland Van Wijk, Eduard P A Van Wijk, Herman A van Wietmarschen, Jan van der GreefIn this review article, the authors describe the history and development of research into ultra-weak photon emission (UPE), the faint light naturally emitted by the human body. The scientific understanding of this pheno…
Ultra-weak photon emissionBiophotonReactive oxygen speciesSystems biologyHuman - A++2014
Biophoton signal transmission and processing in the brain
Rendong Tang, Jiapei DaiThis narrative review explores an alternative theory of how brain cells communicate. The traditional view is that the nervous system uses bioelectrical and chemical signals, but these models struggle to explain higher b…
biophotonsUltra-weak photon emissionsBiophotonic transmissionNeural signal transmission and processingNeural circuits - A++2014
Antioxidants, inflammation and cardiovascular disease
Harald Mangge, Kathrin Becker, Dietmar Fuchs, Johanna M GostnerThis narrative review explores the links between inflammation, oxidative stress, and cardiovascular disease (CVD). The authors explain that chronic immune activation in CVD leads to high levels of reactive oxygen specie…
Antioxidative therapy; Atherogenesis; Cardiovascular disease; Homocysteine; Neopterin; Nitric oxide; Oxidative stress; Tetrahydrobiopterin; Tryptophan; Vitamins. - A++2014
Highly sensitive imaging for ultra-weak photon emission from living organisms
Masaki KobayashiThis review article describes research on ultra-weak photon emission (UPE), also known as biophotons, which is faint light spontaneously emitted from living organisms. This light emission is associated with metabolic pr…
biophotonsUltra-weak photon emissionCCDReactive oxygen speciesImaging - A++2014
The role of collagen crosslinks in ageing and diabetes - the good, the bad, and the ugly
Jess G Snedeker, Alfonso GautieriThis narrative review explores how glucose in the body can bind to proteins like collagen, a process called glycation. This process creates crosslinks that can change the mechanical properties and function of connective…
collagenCrosslinksageingadvanced glycation endproductstendon mechanics