Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesSpontaneous ultra-weak photon emission in correlation to inflammatory metabolism and oxidative stress in a mouse model of collagen-induced arthritis
In this animal study, researchers investigated a mouse model of rheumatoid arthritis using two techniques: metabolomics (the analysis of metabolic products) and ultra-weak photon emission (UPE), which measures extremely…
Biological effects of direct and indirect manipulation of the fascial system. Narrative review
This narrative review explores the biological effects of manual fascial therapies. While osteopathic manipulative treatment (OMT) is clinically effective, its underlying mechanisms are not fully understood. The authors…
The effect of pre-exercise vibration stimulation on the exercise-induced muscle damage
This study investigated whether vibration stimulation before or after exercise could reduce exercise-induced muscle damage. Thirty healthy men were divided into three groups: one receiving vibration before exercise, one…
A New Definition of an Acupuncture Meridian
This perspective article proposes a new definition of acupuncture meridians, moving away from the idea of dedicated anatomical vessels. The author suggests that meridians are actually tracts of tissue that become affect…
Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes
This study investigated vitamin C levels in 44 critically ill patients in an intensive care unit (ICU). Researchers found that most patients had low vitamin C levels (hypovitaminosis C), and one-third were severely defi…
Oscillations of ultra-weak photon emission from cancer and noncancer cells stressed by culture medium change and TNF-alfa
All cells spontaneously emit a very faint light, known as ultra-weak photon emission (UPE). This study investigated how this light emission changes when different types of human cells, both cancerous and non-cancerous,…
Vitamin C and Immune Function
This narrative review explores the crucial role of Vitamin C in the human immune system. As a potent antioxidant, it supports various functions in both the innate and adaptive immune responses, from strengthening the sk…
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study
In this retrospective before-after study, researchers investigated the effect of a combination therapy of intravenous vitamin C, hydrocortisone, and thiamine for patients with severe sepsis and septic shock. They compar…
Decorin and biglycan are necessary for maintaining collagen fibril structure, fiber realignment, and mechanical properties of mature tendons
This study on mice investigated the role of two molecules, decorin and biglycan, in maintaining healthy adult tendons. Researchers used a genetic model to remove these molecules from mature patellar tendons after they h…
Improvement of skin condition by oral administration of collagen hydrolysates in chronologically aged mice
This animal study investigated how oral supplementation of collagen hydrolysates derived from fish scales affected chronological skin aging in mice over six months. The researchers found that mice receiving collagen in…
Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer’s disease and a novel protective role for ascorbate
In this animal study, researchers examined mitochondrial function in a mouse model of Alzheimer's disease and in mice with low levels of vitamin C (ascorbate). The results indicated that both the presence of amyloid (as…
A Curious Oversight in Acupuncture Research
In this perspective article, the author argues that current acupuncture hypotheses overlook a crucial factor: the speed at which the treatment takes effect. Observations suggest that communication between acupoints and…