Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2017
EFFECT OF MATRIX RHYTHM THERAPY (MRT) COMBINED WITH PHYSIOTHERAPY INTERVENTION IN FROZEN SHOULDER – A CASE REPORT
Vijay Bhartiya, Shrikant Darade, Sandip Bhagwat, Manjumala RoyThis case report describes the treatment of a 52-year-old man with a painful and stiff right shoulder, diagnosed as frozen shoulder. His condition also involved tendinosis, bursitis, and osteoarthritic changes. The pati…
exercisesfrozen shoulderMRT - A++2017
NAD and the aging process: Role in life, death and everything in between
Claudia C S Chini, Mariana G Tarragó, Eduardo N ChiniThis narrative review explores the vital role of the molecule NAD in cellular health and the aging process. Beyond its traditional role in metabolism, NAD is essential for cell signaling and regulating the epigenetic st…
Aging; CD38; Mitochondrial function; NAD(+); PARP; SIRTUINS - A++2017
Vitamin C and Immune Function
Anitra C Carr, Silvia MagginiThis narrative review explores the crucial role of Vitamin C in the human immune system. As a potent antioxidant, it supports various functions in both the innate and adaptive immune responses, from strengthening the sk…
ascorbate; ascorbic acid; immunity; immune system; neutrophil function; microbial killing; lymphocytes; infection; vitamin C - A++2017
Biological effects of direct and indirect manipulation of the fascial system. Narrative review
Giovanni Parravicini, Andrea BergnaThis narrative review explores the biological effects of manual fascial therapies. While osteopathic manipulative treatment (OMT) is clinically effective, its underlying mechanisms are not fully understood. The authors…
fasciaMyofascial releaseManual TherapyMyofascial manipulation - A++2017
Massage therapy research review
Tiffany FieldThis review summarizes research showing beneficial effects of massage therapy for a wide range of conditions, including prenatal depression, pain syndromes, autoimmune conditions, and issues related to aging. The author…
Massage therapy research review - A++2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study
Paul E Marik, Vikramjit Khangoora, Racquel Rivera, Michael H Hooper, John CatravasIn this retrospective before-after study, researchers investigated the effect of a combination therapy of intravenous vitamin C, hydrocortisone, and thiamine for patients with severe sepsis and septic shock. They compar…
corticosteroid; hydrocortisone; septic shock; thiamine; vitamin C - A++2017
A Curious Oversight in Acupuncture Research
Fletcher KovichIn this perspective article, the author argues that current acupuncture hypotheses overlook a crucial factor: the speed at which the treatment takes effect. Observations suggest that communication between acupoints and…
acupunctureelectrical wavesemiconductionsignal propagation - A++2017
A New Definition of an Acupuncture Meridian
Fletcher KovichThis perspective article proposes a new definition of acupuncture meridians, moving away from the idea of dedicated anatomical vessels. The author suggests that meridians are actually tracts of tissue that become affect…
acupunctureelectrical wavesemiconductionsignal propagation - A++2017
Telocytes: Connective tissue repair and communication cells
Leon ChaitowThis commentary highlights a newly identified type of connective tissue cell called a telocyte. We already know that other cells, like fibroblasts, respond to mechanical forces from manual therapy, influencing tissue re…
mechanotransductiontelocytesinterstitial cellsregeneration - A++2017
Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes
Anitra C Carr, Patrice C Rosengrave, Simone Bayer, Steve Chambers, Jan Mehrtens, Geoff M ShawThis study investigated vitamin C levels in 44 critically ill patients in an intensive care unit (ICU). Researchers found that most patients had low vitamin C levels (hypovitaminosis C), and one-third were severely defi…
Vitamin CsepsisIntensive careHypovitaminosis CCritical illness - A++2017
Oscillations of ultra-weak photon emission from cancer and noncancer cells stressed by culture medium change and TNF-alfa
Pierre Madl, Thomas Verwanger, Mark Geppert, Felix ScholkmannAll cells spontaneously emit a very faint light, known as ultra-weak photon emission (UPE). This study investigated how this light emission changes when different types of human cells, both cancerous and non-cancerous,…
cancerBiophotonultraweak photon emission - A++2017
Spontaneous ultra-weak photon emission in correlation to inflammatory metabolism and oxidative stress in a mouse model of collagen-induced arthritis
Min He, Eduard van Wijk, Herman van Wietmarschen, Mei Wang, Mengmeng Sun, Slavik Koval, Roeland van Wijk, Thomas Hankem…In this animal study, researchers investigated a mouse model of rheumatoid arthritis using two techniques: metabolomics (the analysis of metabolic products) and ultra-weak photon emission (UPE), which measures extremely…
biophotonsUltra-weak photon emissionSystems biologyCollagen-induced arthritisCorrelation networks