Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2024
Ultra-processed foods and food additives in gut health and disease
Kevin Whelan, Aaron S Bancil, James O Lindsay, Benoit ChassaingThis narrative review examines the link between ultra-processed foods (UPFs), food additives, and gastrointestinal health. Research suggests that diets high in UPFs are associated with an increased risk of inflammatory…
gut microbiomfood additives - A+++2024
B-Group Vitamins as Potential Prebiotic Candidates: Their Effects on the Human Gut Microbiome
Raquel Bedani, Ana Clara Candelaria Cucick, Marcela Albuquerque Cavalcanti de Albuquerque, Jean Guy LeBlanc, Susana Mar…This narrative review explores whether B-group vitamins can act as prebiotics by promoting the growth of beneficial gut bacteria. The authors discuss how B-vitamins that are not absorbed in the small intestine can reach…
B-group vitamin bacterial producers; B-group vitamins; intestinal microbiome; microbiome modulators; prebiotic - A+++2024
Therapeutic applications of gut microbes in cardiometabolic diseases: current state and perspectives
Lin Yuan, Ying Li, Moutong Chen, Liang Xue, Juan Wang, Yu Ding, Qihui Gu, Jumei Zhang, Hui Zhao, Xinqiang Xie, Qingping…This narrative review explores the relationship between gut microbiota and cardiometabolic diseases (CMD), such as hypertension, obesity, and type 2 diabetes. The authors describe how gut microbes and their metabolites…
Cardiometabolic disease; Dietary nutrition; Gut microbiome - A+++2024
Gut-Brain Interactions and Their Impact on Astrocytes in the Context of Multiple Sclerosis and Beyond
Julia Zißler, Veit Rothhammer, Mathias LinnerbauerThis narrative review explores how the interaction between the gut microbiome and the brain influences the progression of multiple sclerosis (MS). The researchers describe how imbalances in gut bacteria can lead to bact…
dysbiosis; gut–brain interactions; microbiome; multiple sclerosis; neuroinflammation - A+++2023
Fasting-mimicking diet synergizes with ferroptosis against quiescent, chemotherapy-resistant cells
Xiaoxia Liu, Shaoyong Peng, Guannan Tang, Gaopo Xu, Yumo Xie, Dingcheng Shen, Mingxuan Zhu, Yaoyi Huang, Xiaolin Wang,…This study investigates how a fasting-mimicking diet (FMD) affects colorectal cancer cells, particularly those resistant to chemotherapy. Researchers found that while fasting slows tumor growth, it can also cause cancer…
Autophagy; Colorectal cancer; Drug-tolerant persister cells; Fasting; Ferroptosis; Metabolomics; Quiescent cells - A+++2023
Fasting and fasting mimicking diets in cancer prevention and therapy
Olga Blaževitš, Maira Di Tano, Valter D LongoThis review explores how cycles of fasting-mimicking diets (FMD) may aid in cancer prevention and therapy. FMDs are designed to be safer and more manageable than water-only fasting while potentially protecting healthy c…
cancer treatment; differential stress resistance (DSR); differential stress sensitization (DSS); fasting mimicking diet - A+++2023
Immediate Effects of Instrument-Assisted Soft Tissue Mobilization on Hydration Content in Lumbar Myofascial Tissues: A Quasi-Experiment
Andreas Brandl, Christoph Egner, Monique Schwarze, Rüdiger Reer, Tobias Schmidt, Robert SchleipThis quasi-experimental study investigated how instrument-assisted soft tissue mobilization (IASTM) affects the hydration levels of the lumbar fascia in 21 healthy volunteers. Researchers used bioimpedance analysis to t…
bioimpedance analysis; instrument-assisted soft tissue mobilization; thoracolumbar fascia; water content. - A+++2023
Bioelectronic microfluidic wound healing: a platform for investigating direct current stimulation of injured cell collectives
Sebastian Shaner, Anna Savelyeva, Anja Kvartuh, Nicole Jedrusik, Lukas Matter, José Leal, Maria AsplundThis study investigates how electrical stimulation can accelerate wound healing by mimicking the body's natural electric fields. Researchers developed a bioelectronic microfluidic platform to test the effects of direct…
wound healingDirect current stimulation - A+++2023
Dietary patterns and cardiometabolic health: Clinical evidence and mechanism
Wenting Wang, Yanfei Liu, Yiwen Li, Binyu Luo, Zhixiu Lin, Keji Chen, Yue LiuThis narrative review examines how various dietary patterns influence cardiometabolic health and disease prevention. The researchers emphasize that healthy eating habits, such as the Mediterranean or plant-based diets,…
cardiometabolic disease; clinical evidence; dietary patterns; gut microbiota; mechanism - A+++2023
The Effects of the Mediterranean Diet on Health and Gut Microbiota
Thomas M Barber, Stefan Kabisch, Andreas F H Pfeiffer, Martin O WeickertThis review explores how the Mediterranean Diet, rich in plants, fibers, and olive oil, influences overall health and the gut microbiota. Research suggests that the diet is associated with improved longevity and a reduc…
Mediterranean diet; dietary fibre; gut microbiota; monounsaturated fat - A+++2023
Effectiveness of visceral fascial therapy targeting visceral dysfunctions outcome: systematic review of randomized controlled trials
Fabiana C da Silva, Leonardo S Vieira, Lucas V Santos, Nathaly Gaudreault, Ronaldo H Cruvinel-Júnior, Gilmar M SantosThis systematic review evaluated 11 randomized controlled trials to investigate the effectiveness of visceral fascial therapy for various health conditions. The results suggest that the therapy may help reduce long-term…
painFascial therapyVisceral manipulation therapyVisceral disorders - A+++2023
Impact of Vitamin D Deficiency on Mental Health in University Students
Mansour Almuqbil, Moneer E Almadani, Salem Ahmad Albraiki, Ali Musharraf Alamri, Ahmed Alshehri, Adel Alghamdi, Sultan…This cross-sectional study investigated the relationship between vitamin D deficiency and mental health among 480 university students in Saudi Arabia. The findings revealed that nearly 60% of participants were vitamin D…
Riyadh; Saudi Arabia; anxiety; depression; mental health; psychological burden; stress; university students; vitamin D deficiency