Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2020
Continuous Ascorbate Infusions in the Management of Patients with Advanced Colon Cancer
Nina MikirovaThis study analyzed data from a previous clinical trial involving 17 patients with late-stage colon cancer. The patients received continuous intravenous infusions of vitamin C (ascorbate) over 6-8 weeks. Researchers fou…
Vitamin CAscorbic acidcolon cancer - A+++2020
The role of cannabinoids in the treatment of cancer
L Vecera, T Gabrhelik, P Prasil, P StouracThis review article summarizes current knowledge on how cannabinoids and their receptors modulate tumor diseases. Research suggests that cannabinoids may influence cancer progression by stimulating programmed cell death…
cancer; cannabinoid receptor; cannabinoids; oncological diseases cancer treatment - A+++2020
A Review of the Theoretical Fascial Models: Biotensegrity, Fascintegrity, and Myofascial Chains
Bruno Bordoni, Tom MyersIn this review article, the authors discuss three theoretical models used to understand how fascia functions in the body. The biotensegrity model is mechanical and considers the solid fascia, while the fascintegrity mod…
fasciaMyofascialOsteopathicphysiotherapymyofascial chains - A+++2020
Effects of vitamin C on oxidative stress, inflammation, muscle soreness, and strength following acute exercise: meta-analyses of randomized clinical trials
Natiele Camponogara Righi, Felipe Barreto Schuch, Angélica Trevisan De Nardi, Caroline Montagner Pippi, Geovana de Alme…This meta-analysis compiled results from 18 randomized clinical trials to investigate the effects of vitamin C supplementation following a single bout of exercise. The researchers found that vitamin C reduced certain ma…
inflammationOxidative stressexerciseathleteAscorbic acid - A+++2020
Establishment of a Novel Porcine Model to Study the Impact of Active Stretching on a Local Carrageenan-Induced Inflammation
Dennis Muñoz Vergara, Lisbeth Berrueta, Colleen Carmody, Xingxing An, Peter M Wayne, Ann Marie Zavacki, Helene M Langev…This animal study used a novel porcine model to investigate how active stretching affects controlled inflammation in the connective tissue of the back. Researchers trained pigs to perform a specific stretch twice daily…
Stretch - A+++2020
Effects of resveratrol or estradiol on postexercise endothelial function in estrogen-deficient postmenopausal women
Cemal Ozemek, Kerry L Hildreth, Patrick J Blatchford, K Joseph Hurt, Rachael Bok, Douglas R Seals, Wendy M Kohrt, Kerri…This randomized pilot study investigated how a single dose of resveratrol or estradiol affects endothelial function in postmenopausal women. The findings suggest that while both substances can improve the blood vessels'…
aerobic exercise; endothelial function; nutraceutical; sex hormones; women - A+++2020
Cannabis and cannabidiol (CBD) for the treatment of fibromyalgia
Amnon A Berger, Joseph Keefe, Ariel Winnick, Elasaf Gilbert, Jonathan P Eskander, Cyrus Yazdi, Alan D Kaye, Omar Viswan…This narrative review examines the use of cannabis and cannabidiol (CBD) for treating fibromyalgia, a complex condition that often responds poorly to standard therapies. The authors note that while high-quality randomiz…
CBT; SNRI; SSRI; chronic pain; depression; myalgia. - A+++2020
Diet as a Modulator of Intestinal Microbiota in Rheumatoid Arthritis
Eduardo Dourado, Margarida Ferro, Catarina Sousa Guerreiro, João Eurico FonsecaThis narrative review explores how dietary patterns can influence the gut microbiota in individuals with rheumatoid arthritis (RA). Research indicates that RA patients often exhibit significant differences in their inte…
Mediterranean diet; gut microbiota; probiotics; rheumatoid arthritis - A+++2020
Vitamin D insufficiency as a potential culprit in critical COVID-19 patients
Ruhul Munshi, Mohammad H Hussein, Eman A Toraih, Rami M Elshazli, Christina Jardak, Nasrin Sultana, Mohanad R Youssef,…In this systematic review, researchers analyzed data from six studies to explore the association between vitamin D levels and COVID-19 severity. They found that patients with a poor prognosis had significantly lower ser…
meta-analysisCOVID-19SARS-CoV-2vitamin Doutcome - A+++2020
Antiviral Mechanisms of Vitamin C: A Short Communication Consensus Report
Michael J Gonzalez, Jorge R Miranda-Massari, Jose R Rodriguez, Victor Marcial-Vega, Miguel J Berdiel, Jorge Duconge, St…This 2020 publication is a consensus report from a large group of authors, summarizing agreed-upon points regarding vitamin C. Based on the title, the report details the various mechanisms by which vitamin C may exert a…
Vitamin CAscorbic acidantiviral effects - A+++2020
The immediate effect of IASTM vs. Vibration vs. Light Hand Massage on knee angle repositioning accuracy and hamstrings flexibility: A pilot study
George A Koumantakis, Eleonora Roussou, Georgios A Angoules, Nikolaos A Angoules, Theodoros Alexandropoulos, Georgia Ma…This pilot study compared the immediate effects of three different soft tissue techniques on the hamstrings of 16 healthy men. The techniques were instrument-assisted soft tissue mobilization (IASTM), vibration massage,…
fasciaproprioceptionMassageMuscle tightness - A+++2020
Effects of Cesarean Section and Vaginal Delivery on Abdominal Muscles and Fasciae
Chenglei Fan, Diego Guidolin, Serena Ragazzo, Caterina Fede, Carmelo Pirri, Nathaly Gaudreault, Andrea Porzionato, Vero…This study used ultrasound to compare the abdominal muscles and fascia of women who had a C-section, a vaginal delivery, or had never given birth. Researchers found that both types of delivery were associated with chang…
caesarean section; vaginal delivery; fascia; abdominal muscles; pain; ultrasound