Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2020
Propolis-induced exclusion of colloids: Possible new mechanism of biological action
Magdalena Kowacz, Gerald H PollackThis laboratory study investigates how propolis (bee glue) interacts with water to create an exclusion zone (EZ)—a layer of water that repels solutes and microorganisms. The researchers found that surfaces coated with p…
Colloid-surface repulsion; Exclusion zone; Propolis - A+++2020
The role of cannabinoids in the treatment of cancer
L Vecera, T Gabrhelik, P Prasil, P StouracThis review article summarizes current knowledge on how cannabinoids and their receptors modulate tumor diseases. Research suggests that cannabinoids may influence cancer progression by stimulating programmed cell death…
cancer; cannabinoid receptor; cannabinoids; oncological diseases cancer treatment - A+++2020
Continuous Ascorbate Infusions in the Management of Patients with Advanced Colon Cancer
Nina MikirovaThis study analyzed data from a previous clinical trial involving 17 patients with late-stage colon cancer. The patients received continuous intravenous infusions of vitamin C (ascorbate) over 6-8 weeks. Researchers fou…
Vitamin CAscorbic acidcolon cancer - A+++2020
Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women
Jay Jay Thaung Zaw, Peter R C Howe, Rachel H X WongThis randomized controlled trial investigated how daily resveratrol supplementation affects brain health in postmenopausal women over a 12-month period. Participants took either 75 mg of trans-resveratrol twice daily or…
ageing; cerebrovascular function; cognitive decline; menopause; neurovascular coupling; nutraceutical; phytoestrogen; resveratrol - A+++2020
Effects of vitamin C on oxidative stress, inflammation, muscle soreness, and strength following acute exercise: meta-analyses of randomized clinical trials
Natiele Camponogara Righi, Felipe Barreto Schuch, Angélica Trevisan De Nardi, Caroline Montagner Pippi, Geovana de Alme…This meta-analysis compiled results from 18 randomized clinical trials to investigate the effects of vitamin C supplementation following a single bout of exercise. The researchers found that vitamin C reduced certain ma…
inflammationOxidative stressexerciseathleteAscorbic acid - A+++2020
Diet as a Modulator of Intestinal Microbiota in Rheumatoid Arthritis
Eduardo Dourado, Margarida Ferro, Catarina Sousa Guerreiro, João Eurico FonsecaThis narrative review explores how dietary patterns can influence the gut microbiota in individuals with rheumatoid arthritis (RA). Research indicates that RA patients often exhibit significant differences in their inte…
Mediterranean diet; gut microbiota; probiotics; rheumatoid arthritis - A+++2020
Establishment of a Novel Porcine Model to Study the Impact of Active Stretching on a Local Carrageenan-Induced Inflammation
Dennis Muñoz Vergara, Lisbeth Berrueta, Colleen Carmody, Xingxing An, Peter M Wayne, Ann Marie Zavacki, Helene M Langev…This animal study used a novel porcine model to investigate how active stretching affects controlled inflammation in the connective tissue of the back. Researchers trained pigs to perform a specific stretch twice daily…
Stretch - A+++2020
Prevention and treatment of COVID-19 infection by earthing
Haider Abdul-Lateef MousaThis observational study investigated the effects of 'earthing'—direct physical contact with the ground—in 59 people with COVID-19. Participants engaged in earthing for 15 minutes to 3 hours daily. The author reported t…
COVID-19; COVID-19 treatment; COVID-19 prevention; Earthing; Grounding; cytokine storm - A+++2020
Alterations of Extracellular Matrix Mechanical Properties Contribute to Age-Related Functional Impairment of Human Skeletal Muscles
Piero Pavan, Elena Monti, Michela Bondí, Chenglei Fan, Carla Stecco, Marco Narici, Carlo Reggiani, Lorenzo MarcucciThis study investigated why muscles become stiffer with age by comparing individual muscle fibers to bundles of fibers that include the extracellular matrix (ECM). Researchers found that while the stiffness of individua…
aging; collagen; extracellular matrix; resting tension; single muscle fiber; skeletal muscle. - A+++2020
Effects of resveratrol or estradiol on postexercise endothelial function in estrogen-deficient postmenopausal women
Cemal Ozemek, Kerry L Hildreth, Patrick J Blatchford, K Joseph Hurt, Rachael Bok, Douglas R Seals, Wendy M Kohrt, Kerri…This randomized pilot study investigated how a single dose of resveratrol or estradiol affects endothelial function in postmenopausal women. The findings suggest that while both substances can improve the blood vessels'…
aerobic exercise; endothelial function; nutraceutical; sex hormones; women - A+++2020
Cannabinoids in Medicine: Cancer, Immunity, and Microbial Diseases
Paweł Śledziński, Agnieszka Nowak-Terpiłowska, Joanna ZeylandThis narrative review explores how cannabinoids, including those from plants and those produced naturally by the body, influence health through the endocannabinoid system. The authors describe how these compounds intera…
cancer medicine; cannabinoid receptors; cannabinoids; immune medicine - A+++2020
Long-term resveratrol supplementation improves pain perception, menopausal symptoms, and overall well-being in postmenopausal women: findings from a 24-month randomized, controlled, crossover trial
Jay Jay Thaung Zaw, Peter R C Howe, Rachel H X WongThis 24-month randomized controlled crossover trial investigated the effects of daily resveratrol supplementation in 125 postmenopausal women. The findings suggest that taking 75 mg of resveratrol twice daily may reduce…
Resveratrolpolyphenolemenopause