Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2021
Resveratrol Ameliorates Aortic Calcification in Ovariectomized Rats via SIRT1 Signaling
Sally K Hammad, Rana G Eissa, Mohamed A Shaheen, Nahla N YounisThis animal study on rats investigated how the phytoestrogen resveratrol affects aortic calcification following menopause. Researchers found that resveratrol, similar to estrogen, reduced calcium deposition in arterial…
SIRT1; estrogen; menopause; phytoestrogen; polyphenol; resveratrol; vascular calcification - A+++2021
The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self
Wen G Chen, Dana Schloesser, Angela M Arensdorf, Janine M Simmons, Changhai Cui, Rita Valentino, James W Gnadt, Lisbeth…This review article presents a unified framework for interoception, the process by which the body senses, interprets, and regulates its internal signals. The authors propose an expanded definition that includes bidirect…
autonomic; insula; parasympathetic; spinal; sympathetic; vagal - A+++2021
Evidence of a new hidden neural network into deep fasciae
Caterina Fede, Lucia Petrelli, Diego Guidolin, Andrea Porzionato, Carmelo Pirri, Chenglei Fan, Raffaele De Caro, Carla…In this study on mice, researchers examined the nerve networks within two different types of deep fascia: the thoracolumbar fascia (in the lower back) and the gluteal fascia (around the buttock muscles). They found that…
deep fasciainnervation of fascia. low back pain - A+++2021
Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan
Amrendra Mishra, Hamed Mirzaei, Novella Guidi, Manlio Vinciguerra, Alice Mouton, Marina Linardic, Francesca Rappa, Rosa…This animal study on mice investigated how periodic cycles of a fasting-mimicking diet (FMD) affect health when consuming a high-fat, high-calorie diet. Researchers found that five days of FMD every month reduced the ac…
fasting; fasting-mimicking diet; inflammation; intermittent fasting; high fat diet; cardiovascular disease - A+++2021
Fascia Mobility, Proprioception, and Myofascial Pain
Helene M LangevinThe body's fascial network is a crucial, yet often overlooked, component of the musculoskeletal system. Its ability to allow muscles and other tissues to slide past one another is essential for healthy movement and may…
fascia; interoception; proprioception; myofascial pain; connective tissue; fascia mobility - A+++2021
Endocannabinoids and the Gut-Brain Control of Food Intake and Obesity
Nicholas V DiPatrizioThis narrative review explores how the endocannabinoid system in the upper gastrointestinal tract regulates gut-brain communication to control food intake and energy balance. Research suggests that these lipid-derived s…
CB1 receptor; endocannabinoid; food intake; gut-brain; intestine; reward - A+++2021
Vitamins, the gut microbiome and gastrointestinal health in humans
Van T Pham, Susanne Dold, Ateequr Rehman, Julia K Bird, Robert E SteinertThis narrative review explores how various vitamins influence the gut microbiome and gastrointestinal health in humans. The research suggests that vitamins such as A, B, C, D, and E may increase the diversity of benefic…
Gastrointestinal health; Gut; Gut barrier function; Microbiome; Micronutrient; Vitamins - A+++2021
Psychological and biological resilience modulates the effects of stress on epigenetic aging
Zachary M Harvanek, Nia Fogelman, Ke Xu, Rajita SinhaChronic stress is linked to negative health outcomes, and this study explored its connection to accelerated biological aging. Researchers evaluated 444 adults, measuring their cumulative stress, biological age using an…
AgingStresspsychological morbidityanxityepigenetic - A+++2021
https://drive.google.com/open?id=1AwvV87ryOvdUlyj-PBPhiMGpiWQenN8T&authuser=camilla%40atlasbalans.com&usp=drive_fs
Vibeke Sødring Elbrønd, Rikke M SchultzThis dissection study on 44 horses investigated the deep myofascial kinetic lines, which are continuous chains of connective tissue and muscle. Researchers verified the existence of a Deep Ventral Line (DVL) in horses,…
Myofascial LinesDeep Ventral LineDeep Dorsal LineDeep Adduction LineDeep Abduction Line - A+++2021
Cannabinoids in Breast Cancer: Differential Susceptibility According to Subtype
Cristina Ferreira Almeida, Natércia Teixeira, Georgina Correia-da-Silva, Cristina AmaralThis narrative review explores how different subtypes of breast cancer respond to cannabinoids like THC and CBD. Research suggests that estrogen receptor-negative cells may be more susceptible to these compounds than ho…
Cannabis sativa; anandamide; breast cancer; cannabidiol; cannabidivarin; cannabigerol; cannabinoids; cannabinol; Δ9-tetrahydrocannabinol - A+++2021
Menopause and the Skin: Old Favorites and New Innovations in Cosmeceuticals for Estrogen-Deficient Skin
Edwin D Lephart, Frederick NaftolinThis narrative review explores how the decline in estrogen levels during menopause significantly impacts skin health and structural integrity. The loss of estrogen leads to reduced collagen and elastin production, along…
4′-Acetoxy resveratrol; Aging; Cosmeceuticals; Equol; Estrogen; Estrogen deficient skin; Hormone therapy; Menopause; Polyphenols; Skin - A+++2021
Potential Nociceptive Role of the Thoracolumbar Fascia: A Scope Review Involving In Vivo and Ex Vivo Studies
Larissa Sinhorim, Mayane Dos Santos Amorim, Maria Eugênia Ortiz, Edsel Balduino Bittencourt, Gianluca Bianco, Fabiana C…This scoping review compiles research on how the thoracolumbar fascia (TLF) in the lower back contributes to pain perception. By examining both animal and human studies, the authors find that the fascia is richly suppli…
ex vivo; fascia; in vivo; innervation; lower back pain; nociceptor; pain; scoping review; thoracolumbar fascia