Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2021
Fascial thickness and stiffness in hypermobile Ehlers-Danlos syndrome
Tina J Wang, Antonio SteccoResearchers investigated fascial changes in people with hypermobile Ehlers-Danlos Syndrome (hEDS), a condition often associated with widespread pain. They used ultrasound and elastography to compare fascial thickness an…
deep fasciaconnective tissue disorderhypermobile Ehlers-Danlos syndromeultrasound elastography - A+++2021
Connecting brain and body: Transdiagnostic relevance of connective tissue variants to neuropsychiatric symptom expression
Harriet Emma Clare Sharp, Hugo D Critchley, Jessica A EcclesThis narrative review explores the growing evidence linking joint hypermobility, a common connective tissue variant, with a range of psychiatric conditions. The authors summarize the well-established connection to anxie…
Hypermobile Ehlers-Danlos syndrome; Joint hypermobility; Mind-body relations; Neurodevelopmental disorders; Psychiatric disorders; Psychopathology. - A+++2021
Endocannabinoids and the Gut-Brain Control of Food Intake and Obesity
Nicholas V DiPatrizioThis narrative review explores how the endocannabinoid system in the upper gastrointestinal tract regulates gut-brain communication to control food intake and energy balance. Research suggests that these lipid-derived s…
CB1 receptor; endocannabinoid; food intake; gut-brain; intestine; reward - A+++2021
Osteogenic effect of low-intensity pulsed ultrasound and whole-body vibration on peri-implant bone. An experimental in vivo study
Kenta Shobara, Toru Ogawa, Aya Shibamoto, Makiko Miyashita, Akiyo Ito, Ratri M SitalaksmiThis animal study in rats investigated whether low-intensity pulsed ultrasound (LIPUS) and whole-body vibration (WBV) could improve bone healing around titanium implants. Researchers compared the effects of LIPUS alone,…
low-intensity pulsed ultrasound (LIPUS); low-magnitude high-frequency loading; osseointegration; osteogenesis; prostheses and implants. - A+++2021
The Molecular Targets of Cannabinoids in the Treatment of Cancer and Inflammation
Alenabi Aylar, Malekinejad HassanThis narrative review examines how cannabinoids influence inflammation and cancer by interacting with the body's endocannabinoid system. The researchers describe how endogenous, plant-derived, and synthetic compounds ta…
Cannabinoids; anti-proliferative effects; apoptosis; cancer; cell proliferation; inflammation - A+++2021
Cannabinoids in the landscape of cancer
Nagina Mangal, Simon Erridge, Nagy Habib, Anguraj Sadanandam, Vikash Reebye, Mikael Hans SodergrenThis narrative review explores how cannabinoids—including plant-derived, endogenous, and synthetic versions—interact with cancer in laboratory and animal models. The research suggests that these compounds may inhibit tu…
Cancer; Cannabidiol; Cannabinoid receptors; Cannabinoids; Endocannabinoid system; Tetrahydrocannabinol - A+++2021
An acupoint-originated human interstitial fluid circulatory network
HongYi Li, Fang Wang, Min Chen, Zhi-Jian Zheng, Ya-Jun Yin, Jun Hu, Hua Li, Andreas Sammer, Georg Feig, Norbert Maurer,…Details from this study have not yet been summarized. The study's title is "An acupoint-originated human interstitial fluid circulatory network". This title suggests the authors are proposing a circulatory network for i…
meridiansacupointsinterstitium - A+++2021
Low frequency weak electric fields can induce structural changes in water
Iman Rad, Rainer Stahlberg, Kurt Kung, Gerald H PollackThis study investigated how weak, low-frequency electric fields affect the structure of different types of water, including "exclusion zone" (EZ) water. Researchers found that exposure to these fields, even without dire…
EZ waterfourth phase of water - A+++2021
The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review
Mishti Khatri, Robert J Naughton, Tom Clifford, Liam D Harper, Liam CorrThis systematic review evaluated 15 randomized controlled trials on how collagen peptide supplementation interacts with exercise to affect joint health and recovery. The findings suggest that collagen may be most effect…
Fat free mass; Gelatin; Joint health; Joint pain; Muscle damage; Protein - A+++2021
Soft Tissue Manipulation May Attenuate Inflammation, Modulate Pain, and Improve Gait in Conscious Rodents With Induced Low Back Pain
M Terry Loghmani, Carolyn Tobin, Colleen Quigley, Alanna FennimoreThis animal study on rodents explored how instrument-assisted soft tissue manipulation (IASTM) affects pain, gait, and inflammation in cases of low back pain. The researchers found that the treatment suggests an ability…
rehabilitation - A+++2021
Reconnecting the Brain with the Rest of the Body in Musculoskeletal Pain Research
Helene M LangevinIn this commentary, the author argues that musculoskeletal pain research is often siloed into separate specialties like neuroscience, physical therapy, orthopedics, and rheumatology. This separation creates gaps in know…
Musculoskeletal pain; chronic pain; muscle; connective tissue; mind and body practices - A+++2021
Parameter-Dependency of Low-Intensity Vibration for Wound Healing in Diabetic Mice
Rita E Roberts, Onur Bilgen, Rhonda D Kineman, Timothy J KohIn this animal study on diabetic mice, researchers investigated how different settings of low-intensity vibration affect wound healing. The mice were exposed to various combinations of vibration frequency and accelerati…
wound healingAngiogenesisgrowth factorsdiabeteslow-intensity vibration