Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2021
Endocannabinoids and the Gut-Brain Control of Food Intake and Obesity
Nicholas V DiPatrizioThis narrative review explores how the endocannabinoid system in the upper gastrointestinal tract regulates gut-brain communication to control food intake and energy balance. Research suggests that these lipid-derived s…
CB1 receptor; endocannabinoid; food intake; gut-brain; intestine; reward - A+++2021
Variant connective tissue (joint hypermobility) and dysautonomia are associated with multimorbidity at the intersection between physical and psychological health
Jenny L L Csecs, Nicholas G Dowell, Georgia K Savage, Valeria Iodice, Christopher J Mathias, Hugo D Critchley, Jessica…This study investigated the links between joint hypermobility, autonomic nervous system dysfunction (dysautonomia), and anxiety in adults with mental health or neurodevelopmental conditions. Researchers found that this…
joint hypermobilityAnxietyautonomic dysfunctionmultimorbidity - A+++2021
Psychological and biological resilience modulates the effects of stress on epigenetic aging
Zachary M Harvanek, Nia Fogelman, Ke Xu, Rajita SinhaChronic stress is linked to negative health outcomes, and this study explored its connection to accelerated biological aging. Researchers evaluated 444 adults, measuring their cumulative stress, biological age using an…
AgingStresspsychological morbidityanxityepigenetic - A+++2021
Menopause and the Skin: Old Favorites and New Innovations in Cosmeceuticals for Estrogen-Deficient Skin
Edwin D Lephart, Frederick NaftolinThis narrative review explores how the decline in estrogen levels during menopause significantly impacts skin health and structural integrity. The loss of estrogen leads to reduced collagen and elastin production, along…
4′-Acetoxy resveratrol; Aging; Cosmeceuticals; Equol; Estrogen; Estrogen deficient skin; Hormone therapy; Menopause; Polyphenols; Skin - A+++2021
Nutrition Provides the Essential Foundation for Optimizing Mental Health
Julia J Rucklidge, Jeanette M Johnstone, Bonnie J KaplanThis review article explores the critical link between nutrition and mental health, written to guide psychologists in their clinical practice. The authors outline how a whole-foods diet supports brain function through v…
Vitamins; minerals; nutrition; nutrients; treatment; mental health - A+++2021
Low frequency weak electric fields can induce structural changes in water
Iman Rad, Rainer Stahlberg, Kurt Kung, Gerald H PollackThis study investigated how weak, low-frequency electric fields affect the structure of different types of water, including "exclusion zone" (EZ) water. Researchers found that exposure to these fields, even without dire…
EZ waterfourth phase of water - A+++2021
Cannabinoids in Breast Cancer: Differential Susceptibility According to Subtype
Cristina Ferreira Almeida, Natércia Teixeira, Georgina Correia-da-Silva, Cristina AmaralThis narrative review explores how different subtypes of breast cancer respond to cannabinoids like THC and CBD. Research suggests that estrogen receptor-negative cells may be more susceptible to these compounds than ho…
Cannabis sativa; anandamide; breast cancer; cannabidiol; cannabidivarin; cannabigerol; cannabinoids; cannabinol; Δ9-tetrahydrocannabinol - A+++2021
The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self
Wen G Chen, Dana Schloesser, Angela M Arensdorf, Janine M Simmons, Changhai Cui, Rita Valentino, James W Gnadt, Lisbeth…This review article presents a unified framework for interoception, the process by which the body senses, interprets, and regulates its internal signals. The authors propose an expanded definition that includes bidirect…
autonomic; insula; parasympathetic; spinal; sympathetic; vagal - A+++2021
Effect of vibration therapy on physical function in critically ill adults (VTICIA trial): protocol for a single-blinded randomised controlled trial
Nobuto Nakanishi, Satoshi Doi, Yoshimi Kawahara, Mie Shiraishi, Jun OtoThis is a protocol for a randomized controlled trial designed to investigate the effect of vibration therapy for critically ill adults. The researchers plan to enroll 188 intensive care unit (ICU) patients and randomly…
vibration therapydeliriummuscle atrophy - A+++2021
Intermittent and periodic fasting, longevity and disease
Valter D Longo, Maira Di Tano, Mark P Mattson, Novella GuidiThis narrative review explores how intermittent fasting (IF) and periodic fasting (PF) may influence longevity and healthspan by acting on cellular aging processes. The authors describe how fasting periods ranging from…
fasting; fasting-mimicking diet; inflammation; intermittent fasting - A+++2021
The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review
Mishti Khatri, Robert J Naughton, Tom Clifford, Liam D Harper, Liam CorrThis systematic review evaluated 15 randomized controlled trials on how collagen peptide supplementation interacts with exercise to affect joint health and recovery. The findings suggest that collagen may be most effect…
Fat free mass; Gelatin; Joint health; Joint pain; Muscle damage; Protein - A+++2021
Connecting brain and body: Transdiagnostic relevance of connective tissue variants to neuropsychiatric symptom expression
Harriet Emma Clare Sharp, Hugo D Critchley, Jessica A EcclesThis narrative review explores the growing evidence linking joint hypermobility, a common connective tissue variant, with a range of psychiatric conditions. The authors summarize the well-established connection to anxie…
Hypermobile Ehlers-Danlos syndrome; Joint hypermobility; Mind-body relations; Neurodevelopmental disorders; Psychiatric disorders; Psychopathology.