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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 37–48 of 221 studies · page 4/19A+++
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A+++2021

Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan

Amrendra Mishra, Hamed Mirzaei, Novella Guidi, Manlio Vinciguerra, Alice Mouton, Marina Linardic, Francesca Rappa, Rosa…

This animal study on mice investigated how periodic cycles of a fasting-mimicking diet (FMD) affect health when consuming a high-fat, high-calorie diet. Researchers found that five days of FMD every month reduced the ac…

fasting; fasting-mimicking diet; inflammation; intermittent fasting; high fat diet; cardiovascular disease
A+++2021

The challenges of chronic pain and fatigue

Jessica A Eccles, Kevin A Davies

In this review article, the authors explore the challenges of chronic pain and fatigue, two common and frequently overlapping symptoms. They discuss possible underlying biological associations, including connective tiss…

Fibromyalgiapainfatigue
A+++2021

Evidence for continuity of interstitial spaces across tissue and organ boundaries in humans

Odise Cenaj, Douglas H R Allison, Rami Imam, Briana Zeck, Lilly M Drohan, Luis Chiriboga, Jessica Llewellyn, Cheng Z Li…

Researchers investigated whether the fluid-filled spaces within our connective tissues, known as the interstitium, are isolated within organs or form a continuous network throughout the body. By tracking particles like…

continuityinterstitiumfluid
A+++2021

Estrogenic Effect of Salvia officinalis Extract on Reproductive Function of Female Mice and Identification of Its Phenolic Content

Sabah H Elgayed, Elham A Afify, Hanan A Amin, Ahmed A H Abdellatif

This animal study on mice investigated whether sage (Salvia officinalis) extract could serve as a natural alternative to estrogen replacement therapy. Researchers found that sage contains phytoestrogens, specifically qu…

Natural phytoestrogens; female mice.; menopause; natural estrogen; phenolic content; saliva officinalis; uterotrophic activity
A+++2021

Potential Nociceptive Role of the Thoracolumbar Fascia: A Scope Review Involving In Vivo and Ex Vivo Studies

Larissa Sinhorim, Mayane Dos Santos Amorim, Maria Eugênia Ortiz, Edsel Balduino Bittencourt, Gianluca Bianco, Fabiana C…

This scoping review compiles research on how the thoracolumbar fascia (TLF) in the lower back contributes to pain perception. By examining both animal and human studies, the authors find that the fascia is richly suppli…

ex vivo; fascia; in vivo; innervation; lower back pain; nociceptor; pain; scoping review; thoracolumbar fascia
A+++2021

Vitamins, the gut microbiome and gastrointestinal health in humans

Van T Pham, Susanne Dold, Ateequr Rehman, Julia K Bird, Robert E Steinert

This narrative review explores how various vitamins influence the gut microbiome and gastrointestinal health in humans. The research suggests that vitamins such as A, B, C, D, and E may increase the diversity of benefic…

Gastrointestinal health; Gut; Gut barrier function; Microbiome; Micronutrient; Vitamins
A+++2021

The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review

Mishti Khatri, Robert J Naughton, Tom Clifford, Liam D Harper, Liam Corr

This systematic review evaluated 15 randomized controlled trials on how collagen peptide supplementation interacts with exercise to affect joint health and recovery. The findings suggest that collagen may be most effect…

Fat free mass; Gelatin; Joint health; Joint pain; Muscle damage; Protein
A+++2021

Myofascial pain in females and personalized care: The key role played by sex hormones

Caterina Fede, Carmelo Pirri, Raffaele De Caro, Carla Stecco

Based on its title, this publication appears to explore the relationship between sex hormones and myofascial pain specifically in females. The authors suggest that hormonal factors play a key role in this type of pain.…

Myofascial painsex hormonesfemales
A+++2021

Fascia Focused Manual Therapy Interventions-Proposed Treatment for Post-COVID Syndrome

John Sharkey

This report proposes that fascia-focused manual therapies may be an appropriate treatment for patients with post-COVID syndrome. The author suggests that many of the long-term symptoms following COVID-19, such as soft t…

Coronavirus. Fascia. Post-COVID Syndrome. Long-term COVIDpost-COVID-19 syndrome. Hyaluronan. Angiotensin-converting enzyme 2 [ACE2]. Cytokines
A+++2021

Low frequency weak electric fields can induce structural changes in water

Iman Rad, Rainer Stahlberg, Kurt Kung, Gerald H Pollack

This study investigated how weak, low-frequency electric fields affect the structure of different types of water, including "exclusion zone" (EZ) water. Researchers found that exposure to these fields, even without dire…

EZ waterfourth phase of water
A+++2021

Effect of vibration therapy on physical function in critically ill adults (VTICIA trial): protocol for a single-blinded randomised controlled trial

Nobuto Nakanishi, Satoshi Doi, Yoshimi Kawahara, Mie Shiraishi, Jun Oto

This is a protocol for a randomized controlled trial designed to investigate the effect of vibration therapy for critically ill adults. The researchers plan to enroll 188 intensive care unit (ICU) patients and randomly…

vibration therapydeliriummuscle atrophy
A+++2021

Cannabinoids in the landscape of cancer

Nagina Mangal, Simon Erridge, Nagy Habib, Anguraj Sadanandam, Vikash Reebye, Mikael Hans Sodergren

This narrative review explores how cannabinoids—including plant-derived, endogenous, and synthetic versions—interact with cancer in laboratory and animal models. The research suggests that these compounds may inhibit tu…

Cancer; Cannabidiol; Cannabinoid receptors; Cannabinoids; Endocannabinoid system; Tetrahydrocannabinol