Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2023
The application and trend of ultra-weak photon emission in biology and medicine
Jinxin Du, Tingting Deng, Baorui Cao, Zhiying Wang, Meina Yang, Jinxiang HanThis review article examines ultra-weak photon emission (UPE), a phenomenon where living organisms emit extremely faint light as part of their biological functions. Research has shifted from understanding basic mechanis…
TCM research; oxidative stress; reactive oxygen species (ROS); ultra-weak bioluminescence; ultra-weak photon emission - A+++2023
Regulation of gut microbiota by vitamin C, vitamin E and β-carotene
Xin-Yu Li, Lei Meng, Liang Shen, Hong-Fang JiThis review article summarizes research on how the antioxidants vitamin C, vitamin E, and β-carotene influence the gut microbiota. By analyzing 19 studies, the authors found that these nutrients may alter the compositio…
Gut microbiota; Vitamin C; Vitamin E; β-carotene - A+++2023
Pulsed Electromagnetic Fields (PEMF)-Physiological Response and Its Potential in Trauma Treatment
Jonas Flatscher, Elizabeth Pavez Loriè, Rainer Mittermayr, Paul Meznik, Paul Slezak, Heinz Redl, Cyrill SlezakThis narrative review examines the use of Pulsed Electromagnetic Fields (PEMF) as a non-invasive method to promote healing in trauma, primarily within orthopedics. Despite decades of research and observed positive clini…
PEMF; biophysical forces; cellular signaling; clinical use; electromagnetic field; regeneration - A+++2022
H2 Inhibits the Formation of Neutrophil Extracellular Traps
Kohsuke Shirakawa, Eiji Kobayashi, Genki Ichihara, Hiroki Kitakata, Yoshinori Katsumata, Kazuhisa Sugai, Yoji Hakamata,…This study investigates how molecular hydrogen (H2) may inhibit the formation of neutrophil extracellular traps (NETs), which are web-like DNA structures released by the immune system. While NETs help fight infections,…
BALbronchoalveolar lavage; CVDcardiovascular disease; CitH3citrullinated histone H3; H2; HOClhypochlorous acid; LPS - A+++2022
The Olympic motto through the lens of equestrian sports
Sarah Jane Hobbs, Hilary M ClaytonThis feature article examines the biomechanics of horses across the three Olympic equestrian disciplines: eventing, show jumping, and dressage. The authors describe how the equine body adapts to meet demands for speed,…
horsecentre of massdressageeventingjumping - A+++2022
Pilot study assessing the effect of Fascial Manipulation on fascial densifications and associated pain
Emmett Hughes, Jessica M Koenig, Robert S Lee, Kena McDermott, Tina Freilicher, Mark H PitcherThis pilot study investigated if Fascial Manipulation (FM) could reduce the thickness of fascial densifications and the acute pain associated with them. Researchers used ultrasound to measure densifications and asked pa…
Fascial manipulation; pain; densification; sex differences; diagnostic ultrasound - A+++2022
Fetal Fascial Reinforcement Development: From “a White Tablet” to a Sculpted Precise Organization by Movement
Carmelo Pirri, Lucia Petrelli, Albert Pérez-Bellmunt, Sara Ortiz-Miguel, Caterina Fede, Raffaele De Caro, Maribel Migue…This study examined the development of fascia and retinacula (connective tissue reinforcements) in six human fetuses between 24 and 40 weeks of gestation. The researchers found that deep fascia initially lacks organized…
fetus; fascia development; retinacula; gross functional movements - A+++2022
Hyaluronan homeostasis and its role in pain and muscle stiffness
Adam Amir, Soo Kim, Antonio Stecco, Michael P Jankowski, Preeti RaghavanThis narrative review explores the role of hyaluronan (HA) in the musculoskeletal system. HA is a key component of the extracellular matrix in muscles and fascia, where it normally functions as a lubricant and shock abs…
hyaluronanpainmuscle stiffness - A+++2022
Performance of Swedish Warmblood fragile foal syndrome carriers and breeding prospects
Michela Ablondi, Martin Johnsson, Susanne Eriksson, Alberto Sabbioni, Åsa Gelinder Viklund, Sofia MikkoThis research article investigated the prevalence of Warmblood fragile foal syndrome (WFFS) in Swedish Warmblood horses and its potential link to performance. WFFS is a lethal genetic defect affecting collagen stability…
FFSWFFS - A+++2022
The Effects of Aging on the Intramuscular Connective Tissue
Caterina Fede, Chenglei Fan, Carmelo Pirri, Lucia Petrelli, Carlo Biz, Andrea Porzionato, Veronica Macchi, Raffaele De…This study investigated how intramuscular connective tissue changes with age in both humans and mice. Researchers found that the amount of stiff collagen (Type I) increases significantly with age, while levels of hyalur…
aging; collagen; extracellular matrix; hyaluronan; intramuscular connective tissue; motor control; muscle - A+++2022
Fascial Innervation: A Systematic Review of the Literature
Vidina Suarez-Rodriguez, Caterina Fede, Carmelo Pirri, Lucia Petrelli, Juan Francisco Loro-Ferrer, David Rodriguez-Ruiz…This systematic review examines current evidence regarding the innervation of deep fascia and its potential role in myofascial pain. The findings suggest that fascia is not merely an inert wrapping but a sophisticated s…
fascia; innervation; nociceptor; pain - A+++2022
Magnetic fields induce exclusion zones in water
Valery Shalatonin, Gerald H PollackThis study explores how static magnetic fields influence water by creating "exclusion zones" (EZ), areas where particles are pushed away from the magnet's poles. Researchers observed that these zones form at both the no…
EZ waterfourth phase of waterexclusion zonesmagnetic fields