Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesA long-distance fluid transport pathway within fibrous connective tissues in patients with ankle edema
This anatomical study investigated how fluid might drain from swollen ankles. Researchers injected a fluorescent dye into the skin of four lower legs scheduled for amputation to trace fluid movement. They observed that…
A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms
This study investigates how a periodic fasting-mimicking diet (FMD) affects symptoms of multiple sclerosis (MS) using mouse models and preliminary human trials. In animal models, the diet reduced inflammation and promot…
Effects of whole body vibration exercises on bone mineral density of women with postmenopausal osteoporosis without medications: novel findings and literature review
This systematic review examines the effects of whole-body vibration (WBV) exercises on bone mineral density in postmenopausal women with osteoporosis who are not taking medication. By analyzing twelve studies, researche…
Clinical applications of vibration therapy in orthopaedic practice
This literature review examines the use of vibration therapy in orthopedic practice. Researchers analyzed 71 studies to understand its effects on bone, muscles, and tendons. The review notes that inconsistencies in appl…
Ultrasound Evaluation of the Combined Effects of Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model
This animal study used pigs to investigate how back fascia responds to injury and restricted movement. Researchers created a small injury in the thoracolumbar fascia and also limited movement in some of the pigs for eig…
Understanding Mechanobiology: Physical Therapists as a Force in Mechanotherapy and Musculoskeletal Regenerative Rehabilitation
This perspective article explores the field of mechanobiology and how physical therapists use mechanical forces to promote tissue healing. It explains that cells in our muscles, bones, and tendons respond to physical st…
Efficacy of an orally administered combination of hyaluronic acid, chondroitin sulfate, curcumin and quercetin for the prevention of recurrent urinary tract infections in postmenopausal women
This prospective study evaluated whether an oral supplement containing hyaluronic acid, chondroitin sulfate, curcumin, and quercetin could prevent recurrent urinary tract infections (UTIs) in postmenopausal women. Resea…
Manual evaluation of the diaphragm muscle
The diaphragm is a vital muscle for breathing, but it also plays a key role in posture, organ function, and even emotional states. Despite its importance, there is little scientific literature on how to manually assess…
Vitamin C and Heart Health: A Review Based on Findings from Epidemiologic Studies
This review examines the relationship between vitamin C and heart health by analyzing data from epidemiological studies and clinical trials. Research suggests that vitamin C may protect blood vessels by preventing the o…
Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells
This study used a 3D in vitro model to investigate how the density of the collagen matrix influences the metabolism of breast cancer cells. The researchers observed that a high-density extracellular matrix drives a meta…
Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?
This narrative review explores the link between oxidative stress and inflammation, focusing on how plant-derived polyphenols may mitigate these processes. Oxidative stress occurs when reactive oxygen species overwhelm t…
Nutraceutical supplement in the management of tendinopathies: a systematic review
This systematic review examines the effects of various nutraceuticals, such as glucosamine, chondroitin, vitamin C, and curcumin, in managing tendon disorders. While preclinical research on cells and animals shows promi…