Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2017
Therapeutic effectiveness of instrument-assisted soft tissue mobilization for soft tissue injury: mechanisms and practical application
Jooyoung Kim, Dong Jun Sung, Joohyung LeeThis narrative review explores the mechanisms and practical use of Instrument-Assisted Soft Tissue Mobilization (IASTM) for treating soft tissue injuries. IASTM involves using specialized tools to apply mechanical press…
Injury; Instrument-assisted soft tissue mobilization; Pain; Range of motion; Soft tissue function. - A+++2017
Activation of type 2 cannabinoid receptor (CB2R) by selective agonists regulates the deposition and remodelling of the extracellular matrix
Tao Guan, Guiyang Zhao, Honghui Duan, Yang Liu, Feng ZhaoThis in vitro study investigated how activating the type 2 cannabinoid receptor (CB2R) affects scar formation in eye connective tissue after surgery. Researchers found that human Tenon’s fibroblasts express these recept…
Matrix metalloproteinase 1 (MMP-1); Tenon’s fibroblasts; Transforming growth factor-β1; Type 2 cannabinoid receptor (CB2R); Wound healing - A+++2017
Resveratrol regulates body weight in healthy and ovariectomized rats
Rupali Sharma, Neel Kamal Sharma, M ThungapathraThis animal study on rats investigated how the plant compound resveratrol affects body weight in both healthy subjects and those who had undergone ovariectomy, a model for menopause. The results suggest that resveratrol…
OVX; Ovariectomy; Resveratrol; Soya free diet - A+++2017
Resveratrol Treatment Normalizes the Endothelial Function and Blood Pressure in Ovariectomized Rats
Victor Fabricio, Jorge Camargo Oishi, Bruna Gabriele Biffe, Leandro Dias Gonçalves Ruffoni, Karina Ana da Silva, Keico…This animal study on rats investigated how resveratrol affects blood pressure and vascular function during estrogen deficiency, mimicking post-menopausal conditions. Researchers found that a lack of estrogen led to high…
blood pressureresveratrolPostmenopause - A+++2017
Shielding of the geomagnetic field reduces hydrogen peroxide production in human neuroblastoma cell and inhibits the activity of CuZn superoxide dismutase
Hai-Tao Zhang, Zi-Jian Zhang, Wei-Chuan Mo, Ping-Dong Hu, Hai-Min Ding, Ying Liu, Qian Hua, Rong-Qiao HeThis study investigates how an extremely weak magnetic field, similar to conditions in outer space or shielded environments on Earth, affects human cells. Researchers found that shielding the natural geomagnetic field r…
hydrogen peroxide; hypomagnetic field; oxidative stress; reactive oxygen species; superoxide dismutase - A+++2017
Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease
Min Wei, Sebastian Brandhorst, Mahshid Shelehchi, Hamed Mirzaei, Chia Wei Cheng, Julia Budniak, Susan Groshen, Wendy J…This randomized controlled trial examined the effects of a fasting-mimicking diet (FMD) on risk factors for age-related diseases in 100 healthy participants. For five consecutive days each month over a three-month perio…
fasting; fasting-mimicking diet; inflammation; intermittent fasting; cancer; diabetes; cardiovascular disease - A+++2017
Electric Nutrition: The Surprising Health and Healing Benefits of Biological Grounding (Earthing)
Stephen T Sinatra, James L Oschman, Gaétan Chevalier, Drew SinatraThis narrative review summarizes research on grounding (earthing), which involves direct physical contact with the Earth's surface. The authors suggest that grounding may provide a form of "electric nutrition" with pote…
Grounding - A+++2017
Proinflammatory Cytokines and Oxidative Stress Decrease the Transport of Dopamine Precursor Tyrosine in Human Fibroblasts
Ravi Vumma, Jessica Johansson, Nikolaos VenizelosThis laboratory study investigated how inflammation and oxidative stress affect the transport of the amino acid tyrosine in human fibroblasts, a type of connective tissue cell. Tyrosine is a crucial precursor for the ne…
Dopamine precursor; Human fibroblasts; Neuropsychiatric disorders; Oxidative stress; Proinflammatory cytokines; Tyrosine transport. - A+++2017
Early versus Delayed Rehabilitation after Acute Muscle Injury
Monika L Bayer, Peter Magnusson, Michael KjaerThis research entry, titled "Early versus Delayed Rehabilitation after Acute Muscle Injury," is currently awaiting a detailed summary. The title suggests it explores the optimal timing for starting rehabilitation follow…
Rehabilitationmuscle injurymechanical loading in rehabilitation - A+++2017
Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes
Chia-Wei Cheng, Valentina Villani, Roberta Buono, Min Wei, Sanjeev Kumar, Omer H Yilmaz, Pinchas Cohen, Julie B Sneddon…This study, involving mice and human pancreatic cells, explores how cycles of a fasting-mimicking diet (FMD) may influence the pancreas's ability to produce insulin. Researchers found that the diet appears to activate g…
fasting; fasting-mimicking diet; inflammation; intermittent fasting; diabetes - A+++2017
Resveratrol supplementation reduces pain experience by postmenopausal women
Rachel H X Wong, Hamish M Evans, Peter R C HoweThis randomized, double-blind, placebo-controlled study investigated whether resveratrol supplementation could reduce pain and improve well-being in postmenopausal women. Over 14 weeks, participants taking 75 mg of resv…
Resveratrolpolyphenolemenopause - A+++2016
Resveratrol attenuated estrogen-deficient-induced cardiac dysfunction: role of AMPK, SIRT1, and mitochondrial function
Zijun Meng, Hongjiang Jing, Lu Gan, Hua Li, Bingde LuoThis animal study investigated how resveratrol, an antioxidant found in red grapes, affects cardiac function in estrogen-deficient mice. Researchers found that resveratrol supplementation significantly improved heart co…
AMPK; Resveratrol; SIRT1; heart; ischemia; mitochondrion