Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2020
Repositioning Vitamin C as a Promising Option to Alleviate Complications associated with COVID-19
Mithila Farjana, Akhi Moni, Abdullah Al Mamun Sohag, Adeba Hasan, Abdul Hannan, Golzar Hossain, Jamal UddinThis narrative review explores the potential of Vitamin C (L-ascorbic acid) for managing complications associated with COVID-19. The authors highlight its known functions, including antioxidant, anti-inflammatory, and i…
COVID-19; SARS-CoV-2; Vitamin C; Immune response; In!ammation - A+++2020
The role of cannabinoids in the treatment of cancer
L Vecera, T Gabrhelik, P Prasil, P StouracThis review article summarizes current knowledge on how cannabinoids and their receptors modulate tumor diseases. Research suggests that cannabinoids may influence cancer progression by stimulating programmed cell death…
cancer; cannabinoid receptor; cannabinoids; oncological diseases cancer treatment - A+++2020
Mini-Review on the Roles of Vitamin C, Vitamin D, and Selenium in the Immune System against COVID-19
Minkyung Bae, Hyeyoung KimThis mini-review discusses how vitamin C, vitamin D, and selenium may affect the immune system in relation to COVID-19. Research suggests that deficiencies in these micronutrients are common in patients with acute respi…
COVID-19; infectious disease; selenium; virus; vitamin C; vitamin D - A+++2020
Perspective: Vitamin D deficiency and COVID-19 severity –plausibly linked by latitude, ethnicity, impacts on cytokines,ACE2 and thrombosis
J M Rhodes, S Subramanian, E Laird, G Griffin, R A KennyThis narrative review explores the potential link between vitamin D deficiency and the severity of COVID-19. The authors observed that countries at higher latitudes, with less sun exposure, had higher COVID-19 mortality…
cytokineCOVID-19vitamin D - A+++2020
Ascorbate as Prophylaxis and Therapy for COVID-19—Update From Shanghai and U.S. Medical Institutions
Richard Z Cheng, Mikhail Kogan, Devra DavisThis 2020 report describes how a medical panel in Shanghai evaluated the use of intravenous (IV) ascorbate, or vitamin C, for patients with severe COVID-19. The panel reviewed existing studies and preliminary data from…
COVID-19public healthglobal healthintravenous ascorbate - A+++2020
Is the VITAMINS RCT indicating potential redundancy between corticosteroids and vitamin C?
Anitra C CarrKnown only by its title, this article appears to be a commentary or analysis of a randomized controlled trial (RCT) known as VITAMINS. The title poses a question about whether there might be a "redundancy," or overlappi…
Vitamin Ccorticosteroidsstress respons - A+++2020
Alterations of Extracellular Matrix Mechanical Properties Contribute to Age-Related Functional Impairment of Human Skeletal Muscles
Piero Pavan, Elena Monti, Michela Bondí, Chenglei Fan, Carla Stecco, Marco Narici, Carlo Reggiani, Lorenzo MarcucciThis study investigated why muscles become stiffer with age by comparing individual muscle fibers to bundles of fibers that include the extracellular matrix (ECM). Researchers found that while the stiffness of individua…
aging; collagen; extracellular matrix; resting tension; single muscle fiber; skeletal muscle. - A+++2020
Collagen supplementation for skin health: A mechanistic systematic review
Meisam Barati, Masoumeh Jabbari, Roya Navekar, Fariba Farahmand, Reihaneh Zeinalian, Ammar Salehi-Sahlabadi, Nasrin Abb…This systematic review evaluates the impact of collagen supplementation on skin health and aging parameters. By analyzing ten clinical trials, researchers found that oral intake of both intact and hydrolyzed collagen co…
M2-like macrophage; collagen; collagen hydrolysate; oral tolerance; regulatory T cell; skin health. - A+++2020
Flavonoids and Other Polyphenols Act as Epigenetic Modifiers in Breast Cancer
Priyanga Selvakumar, Aja Badgeley, Paige Murphy, Hina Anwar, Urvashi Sharma, Katharine Lawrence, Ashakumary Lakshmikutt…This narrative review explores how dietary flavonoids and other polyphenols may influence breast cancer through epigenetic mechanisms. Research suggests that compounds found in green tea, soy, and berries can affect gen…
Epigenetics; breast cancer; chromatin modification; flavonoids; methylation - A+++2020
Healthy fats and exclusion-zone size
Abha Sharma, Gerald H PollackThis study investigated whether healthy fats can contribute to the formation of exclusion-zone (EZ) water, also known as the fourth phase of water. Researchers tested substances such as ghee, coconut oil, and lard to se…
Coconut oil; Exclusion-zone water; Fats; Ghee; Health-promoting function; Lard; UV–VIS spectroscopy - A+++2020
The feasibility and impact of instrument-assisted manual therapy (IAMT) for the lower back on the structural and functional properties of the lumbar area in female soccer players: a randomised, placebo-controlled pilot study design
Patrick Weber, Christine Graf, Werner Klingler, Nadine Weber, Robert SchleipThis is a protocol for a pilot study designed to investigate the feasibility and impact of instrument-assisted manual therapy (IAMT) for the lower back in female soccer players. The researchers plan to compare IAMT with…
Thoracolumbar fasciaMyofascialultrasound.AthletesInstrument-assisted - A+++2020
Gut Microbiota and Cardiovascular Disease
Marco Witkowski, Taylor L Weeks, Stanley L HazenThis review explores how the gut microbiota influences cardiovascular health through the production of specific metabolic byproducts. Research suggests that the link is not merely associative; certain bacterial metaboli…
atherosclerosis; cardiovascular diseases; gastrointestinal microbiome; thrombosis; vascular diseases