Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+2023
A New Player in the Mechanobiology of Deep Fascia: Yes-Associated Protein (YAP)
Carmelo Pirri, Brasilina Caroccia, Andrea Angelini, Maria Piazza, Lucia Petrelli, Ilaria Caputo, Chiara Montemurro, Pie…This study investigated the role of Yes-associated protein (YAP) in the mechanobiology of deep fascia, specifically the thoracolumbar fascia. Researchers analyzed tissue samples from patients and found that YAP acts as…
fascia; thoracolumbar fascia; extracellular matrix; fibroblasts; Yes-associated protein (YAP); remodeling - A+2015
A unifying neuro-fasciagenic model of somatic dysfunction - Underlying mechanisms and treatment - Part II
Paolo TozziThis review paper proposes a new, unifying "neuro-fasciagenic" model for understanding somatic dysfunction. The author argues for a shift in perspective, moving from a purely neurological explanation to one where fascia…
fasciaManual Therapysomatic dysfunctionfascial dysfunctionfascial mechanisms - A+2016
Acute effects of muscle stretching on physical performance, range of motion, and injury incidence in healthy active individuals: a systematic review
David G Behm, Anthony J Blazevich, Anthony D Kay, Malachy McHughThis systematic review examines how different types of stretching (static, dynamic, and PNF) affect performance, range of motion (ROM), and injury risk in healthy individuals. The findings suggest that static stretching…
ballistic stretch; dynamic stretch; facilitation neuromusculaire proprioceptive; flexibility; flexibilité; proprioceptive neuromuscular facilitation; static stretch; warm-up - A+2015
An overview of the beneficial effects of hydrolysed collagen intake on joint and bone health and on skin ageing
Teresa Figueres Juher, Esther Basés PérezThis narrative review summarizes research on hydrolysed collagen (HC) and its impact on joint, bone, and skin health. Evidence suggests that these small collagen peptides are highly bioavailable and accumulate in connec…
supplementationOsteoporosishydrolysate collagenosteartrithis - A+2018
Anatomy of the Superficial Fascia System of the Breast: A Comprehensive Theory of Breast Fascial Anatomy
Robert D Rehnke, Rachel M Groening, Eric R Van Buskirk, John M ClarkeThis study investigated the three-dimensional fascial structure of the breast through 12 cadaver dissections and clinical observations during surgery. The researchers identified a closed system of fascia and fat that su…
superficial fasciabreastreconstructive breast surgerycosmetic breast surgery - A+2020
Ankle Motion Is Associated With Soft Tissue Displacement in the Dorsal Thigh: An in vivo Investigation Suggesting Myofascial Force Transmission Across the Knee Joint
Jan Wilke, Heloise Debelle, Sarah Tenberg, Andrew Dilley, Constantinos MaganarisThis study investigated how ankle motion affects tissue in the back of the thigh. Researchers passively stretched the calves of healthy participants lying prone with an extended knee. Using ultrasound, they observed tha…
fasciamyofascial chainsultrasound.Myofascial force transmissionrange of motion - A+2019
Anti-Inflammatory Diets and Fatigue
Ulrike Hass, Catrin Herpich, Kristina NormanThis narrative review explores the link between pro-inflammatory status and chronic disease-related fatigue in conditions such as cancer, fibromyalgia, and chronic fatigue syndrome. While evidence for individual nutrien…
anti-inflammatory nutrition; cancer; chronic fatigue; cytokines; fatigue reduction diet; inflammation; myalgic encephalomyelitis; omega-3 fatty acids; polyphenols; probiotics. - A+2018
Bone turnover markers after the menopause: T-score approach
Fatma Gossiel, Hibatallah Altaher, David M Reid, Christian Roux, Dieter Felsenberg, Claus-C Glüer, Richard EastellThis study investigated how bone turnover changes in women before and after menopause by measuring specific markers for bone formation (PINP) and bone resorption (CTX). The researchers found that bone turnover increases…
Bone mineral density; Bone turnover markers; Menopause; Osteoporosis - A+2007
Breathing exercises with vagal biofeedback may benefit patients with functional dyspepsia
INA E HJELLAND, SVEN SVEBAK, ARNOLD BERSTAD, GEIR FLATAB, TRYGVE HAUSKENFunctional dyspepsia (FD) is often associated with low vagus nerve tone. This study investigated whether breathing exercises with biofeedback could help. Forty patients with FD were divided into two groups; one group pr…
Biofeedbackbreathing exercisesfunctional dyspepsiavagal tone - A+2014
Cartilage repair using human embryonic stem cell-derived chondroprogenitors
AIXIN CHENG, ZOHER KAPACEE, JIANG PENG, SHIBI LU, ROBERT J LUCAS, TIMOTHY E HARDINGHAM, SUSAN J KIMBERIn this animal study, researchers developed a method to turn human embryonic stem cells into cartilage-forming cells under laboratory conditions. These new cells were then implanted into cartilage defects in the knee jo…
arthritistissue regenerationCell transplantationEmbryonic stem cell - A+2011
Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolysate: a pilot randomized controlled trial
T E McAlindon, M Nuite, N Krishnan, R Ruthazer, L L Price, D Burstein, J Grif!th, K FlechsenharThis pilot randomized controlled trial investigated if collagen hydrolysate supplements could affect knee cartilage in people with mild osteoarthritis. Using a specialized MRI technique (dGEMRIC), researchers tracked ch…
MRIosteoarthritisMagnetic resonance imagingCartilageDelayed gadolinium enhanced - A+2015
Changes in electrical pain threshold of fascia and muscle after initial and secondary bouts of elbow flexor eccentric exercise
Wing Yin Lau, Anthony J. Blazevich, Michael J. Newton, Sam Shi Xuan Wu, Kazunori NosakaThis study investigated how pain sensitivity changes in fascia and muscle after strenuous eccentric exercise. Ten young men performed two bouts of maximal eccentric elbow curls, four weeks apart. After the first session…
pressure pain thresholdmuscle damageRepeated bout effectDelayed onset muscle sorenessVisual analogue scale