Mechanisms of Mechanotransduction, 2006
Topics: Mechanotransduction, Focal adhesion, Extracellular matrix, Cytoskeleton
Authors: A. Wayne Orr, Brian P. Helmke, Brett R. Blackman and Martin A. Schwartz
Essentially all organisms from bacteria to humans are mechanosensitive. Physical forces regulate a large array of physiological processes, and dysregulation of mechanical responses contributes to major human diseases. A survey of both specialized and widely expressed mechanosensitive systems suggests that physical forces provide a general means of altering protein conformation to generate signals. Specialized systems differ mainly in having acquired efficient mechanisms for transferring forces to the mechano-transducers.
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Recently, a German researcher showed that the connective tissue in a human transports 15 l of water in 48 hours, which is a relatively large amount compared to for example the amount of blood and the lymphatic system.
Fascia is a system of flexible connective tissue encapsulating everything in the body. If the system is running smoothly, all is fine, but when some parts become stiff, tense or inflamed, there will be consequences.
What is Fascia? New research shows that it is more than the layer around the muscles. It is a network without beginning or end, from the skin, through the entire body, to the smallest cell.
Connective tissue / fascia is an incredibly adaptable and plastic tissue. It is transformed, remodeled and strengthened or weakened according to the mechanical stimulation (load) to which it is exposed. If we don’t move, the tissue will diminish.
In 2015 veterinary Vibeke S Elbrønd published the first report on Fascia and horses. To make that happen she had to learn all there was regarding fascia, she had to become a fascia expert.
Fascia eller interstitium? Fascian eller interstitium är kroppens arkitektoniska byggnadsstomme med sitt kontinuerliga flöde, som en amerikansk forskargrupp nu alltså anser vara kroppens största organ.
On the Fascia Guide FAQ we have gathered the most common questions and answers about Fascia. Is there anything you would like to know? Visit the page and submit your question.
Exclusive interview with Gil Headly explaining how Fascia changes the perspective on how we look at the body at the 2015 Fascia Research Congress in Washington DC.
New research leads to insights and by looking at the body in a completely new way we get new perspectives and explanations to symptoms and diseases. At the 2015 Joint Conference on Acupuncture, Oncology and Fascia in Boston, research was presented regarding Fascia and Cancer
Here are three major reasons why the Fascia’s central importance to the body’s functionality is not nousehold knowledge. It might be helpful to bare these in mind when relating to current and previous research.