Low-intensity tensile loading increases intratendinous glucose uptake in the Achilles tendon, 2006
Topics: tendon metabolism; tendon mechanical function; connective tissue;
Authors: J. Bojsen-Møller, K. K. Kalliokoski, M. Seppänen, M. Kjaer and S. P. Magnusson
The metabolic activity of tendinous tissues has traditionally been considered to be of limited magnitude. However, recent studies have suggested that glucose uptake increases in the force-transmitting tissues as a response to contractile loading, which in turn indicates an elevated tissue metabolism. The purpose of the present study was to investigate whether such a mechanism could be observed for the human Achilles tendon following tensile loading. Six subjects participated in the study. Unilateral Achilles tendon loading was applied by 25-min intermittent voluntary plantar flexor contractions. A radioactive tracer (I18F]-2-fluoro-2-deoxy-D-glucose) was administered during muscle action, and glucose uptake was measured by use of PET. Regions of interest were defined on the PET images corresponding to the cross section of Achilles tendon at two longitudinally separated sites (insertion and free tendon). Glucose uptake index was determined within respective regions of interest for the active and resting leg. Tendon force during voluntary contractions was 13% of maximal voluntary contraction force. Tendon loading induced an elevated glucose uptake index compared with that of the contralateral resting tendon in the region of tendon insertion (0.13 +- 0.05 vs. 0.09 +- 0.02; P < 0.05) and at the free tendon (0.12 +- 0.01 vs. 0.08 +- 0.02; P < 0.05). The present data suggest that tissue metabolism is elevated in the human Achilles tendon in response to low-intensity loading.
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On the Fascia Guide FAQ we have gathered the most common questions and answers about Fascia. Is there anything you would like to know? Visit the page and submit your question.
Fascia is a system of flexible connective tissue encapsulating everything in the body. If the system is running smoothly, all is fine, but when some parts become stiff, tense or inflamed, there will be consequences.
In the 70s when the orthopedic surgeon Dr. Stephen Levin was at a natural history museum and saw the wires holding up the neck of a dinosaur, he did not get the picture to go together. How could his neck have been held up originally?
In 2015 veterinary Vibeke S Elbrønd published the first report on Fascia and horses. To make that happen she had to learn all there was regarding fascia, she had to become a fascia expert.
Exercise increases collagen production in tendons, ligaments and all Fascia. To stimulate collagen formation in tendons and ligaments, it doesn’t matter if the exercise is eccentric (muscle contraction during extension) or concentric (muscle contraction during shortening).
Banbrytande ny forskning visar hur kollagenproduktionen över hela kroppen påverkas av könshormoner, som t ex östrogen. Läs mer här
From Newton, to Einstein, to the new wildfire of Fascia Research. How do we understand things from a different perspective?
You probably know that the immune system is our defensive wall protecting us from the threats from the outside world – but do you know how it works and how to boost it?
To truly understand Fascia, you must understand the whole. But how do you do that if you have trained all your life to divide and separate?
New research leads to insights and by looking at the body in a completely new way we get new perspectives and explanations to symptoms and diseases. At the 2015 Joint Conference on Acupuncture, Oncology and Fascia in Boston, research was presented regarding Fascia and Cancer